Diabetes
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Distiller, L. A.
Right arrow Articles by Seftel, H. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Distiller, L. A.
Right arrow Articles by Seftel, H. C.
Social Bookmarking
Add to CiteULike   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Diabetes, Vol 24, Issue 4 378-380, Copyright © 1975 by American Diabetes Association

ARTICLES

Pituitary responsiveness to luteinizing hormone-releasing hormone in insulin-dependent diabetes mellitus

LA Distiller, J Sagel, JE Morley and HC Seftel

Impaired fertility and menstrual disturbances are common in diabetes mellitus. In order to study the effect of diabetes on gonadotropin secretion by the pituitary gland, twenty premenopausal diabetic females and seven diabetic males were investigated using luteinizing hormone-releasing hormone (LH-RH). Although the gonadotropes responded to LH-RH in the patients studied, a relative impairment was apparent when compared to normal matched control groups. In the female diabetic patients there was no difference in the gonadotropin responses obtained in those with oligomenorrhea or amenorrhea when compared to those with normal menses. A significant inverse relationship was found between the maximum rise in plasma luteinizing hormone and the fasting plasma glucose. These findings suggest an influence of glucose metabolism on pitiutary gonadotropin function. However, the reduced gonadotropin response is unlikely to be the sole cause of the abnormal gynecologic function.
Add to CiteULike CiteULike   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 Hum ReprodHome page
R.F. Arrais and S.A. Dib
The hypothalamus-pituitary-ovary axis and type 1 diabetes mellitus: a mini review
Hum. Reprod., February 1, 2006; 21(2): 327 - 337.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
J. C. Lopez-Alvarenga, T. Zarinan, A. Olivares, J. Gonzalez-Barranco, J. D. Veldhuis, and A. Ulloa-Aguirre
Poorly Controlled Type I Diabetes Mellitus in Young Men Selectively Suppresses Luteinizing Hormone Secretory Burst Mass
J. Clin. Endocrinol. Metab., December 1, 2002; 87(12): 5507 - 5515.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
B. Baccetti, A. la Marca, P. Piomboni, S. Capitani, E. Bruni, F. Petraglia, and V. De Leo
Insulin-dependent diabetes in men is associated with hypothalamo-pituitary derangement and with impairment in semen quality
Hum. Reprod., October 1, 2002; 17(10): 2673 - 2677.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
A. la Marca, G. Morgante, and V. De Leo
Evaluation of hypothalamic–pituitary–adrenal axis in amenorrhoeic women with insulin-dependent diabetes
Hum. Reprod., February 1, 1999; 14(2): 298 - 302.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Diabetes Diabetes Care Clinical Diabetes Diabetes Spectrum
Copyright © 1975 by the American Diabetes Association.