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Diabetes, Vol 25, Issue 4 241-244, Copyright © 1976 by American Diabetes Association

ARTICLES

Glucose tolerance and insulin release, a mathematical approach I. Assay of the beta-cell response after oral glucose loading

WJ Sluiter, DW Erkelens, WD Reitsma and H Doorenbos

From the dose-response relations between glucose and insulin after oral glucose loading, a reproducible parameter for beta-cell response was deduced. The main advantage of this parameter -corrected insulin response, defined as CIR = I- 100/G(G-70)- lies in it independence from the initial or reached glucose level.
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