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Diabetes, Vol 34, Issue 6 617-619, Copyright © 1985 by American Diabetes Association

ARTICLES

"Cytoplasmic" islet cell antibodies. Evidence that the target antigen is a sialoglycoconjugate

RC Nayak, MA Omar, A Rabizadeh, S Srikanta and GS Eisenbarth

We have biochemically treated (periodate, borohydride, neuraminidase, organic solvents) frozen sections of human pancreas and studied the reactivity of islet-cell-antibody-positive human sera and monoclonal antibodies. The autoantigen of pancreatic sections has the properties of sialic acid containing glycolipid.
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Copyright © 1985 by the American Diabetes Association.