Diabetes
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kava, R. A.
Right arrow Articles by Greenwood, M. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kava, R. A.
Right arrow Articles by Greenwood, M. R.
Social Bookmarking
Add to CiteULike   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Diabetes, Vol 38, Issue 2 159-163, Copyright © 1989 by American Diabetes Association

ARTICLES

Sexual dimorphism of hyperglycemia and glucose tolerance in Wistar fatty rats

RA Kava, DB West, VA Lukasik and MR Greenwood
Biology Department, National Institutes of Health Obesity Research Center, Vassar College, Poughkeepsie, New York 12601.

Obese and lean male and female Wistar fatty rats were fed a high-sucrose (68% of calories) diet from 5 to 22 wk of age. Obese males, but not obese females, developed hyperglycemia in the fed state and were more glucose intolerant during an intragastric glucose tolerance test than obese females. Lean Wistar fatty rats did not become hyperglycemic on the sucrose diet. Obese males also showed a smaller insulin response during the glucose tolerance test than did obese females. The Wistar fatty rat is a sexually dimorphic model of non-insulin-dependent diabetes mellitus in which the male but not the female obese rats become diabetic. The diabetic condition and impaired glucose tolerance in the obese male Wistar fatty rat may be related to impaired pancreatic insulin release and peripheral insulin resistance.
Add to CiteULike CiteULike   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 J EndocrinolHome page
M Fraenkel, J Caloyeras, S-G Ren, and S Melmed
Sex-steroid milieu determines diabetes rescue in pttg-null mice.
J. Endocrinol., June 1, 2006; 189(3): 519 - 528.
[Abstract] [Full Text] [PDF]

Home page
 FASEB J.Home page
T.-S. TSAO, J. LI, K. S. CHANG, A. E. STENBIT, D. GALUSKA, J. E. ANDERSON, J. R. ZIERATH, R. J. MCCARTER, and M. J. CHARRON
Metabolic adaptations in skeletal muscle overexpressing GLUT4: effects on muscle and physical activity
FASEB J, April 1, 2001; 15(6): 958 - 969.
[Abstract] [Full Text] [PDF]

Home page
 HypertensionHome page
T. Yamakawa, S.-i. Tanaka, K. Tamura, F. Isoda, K. Ukawa, Y. Yamakura, Y. Takanashi, Y. Kiuchi, S. Umemura, M. Ishii, et al.
Wistar Fatty Rat Is Obese and Spontaneously Hypertensive
Hypertension, January 1, 1995; 25(1): 146 - 150.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Diabetes Diabetes Care Clinical Diabetes Diabetes Spectrum
Copyright © 1989 by the American Diabetes Association.