Diabetes
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Janka, H. U.
Right arrow Articles by Krolewski, A. S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Janka, H. U.
Right arrow Articles by Krolewski, A. S.
Social Bookmarking
Add to CiteULike   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Diabetes, Vol 38, Issue 4 460-464, Copyright © 1989 by American Diabetes Association

ARTICLES

Risk factors for progression of background retinopathy in long-standing IDDM

HU Janka, JH Warram, LI Rand and AS Krolewski
Research Division, Joslin Diabetes Center, Boston, MA 02215.

Risk factors for the development of severe forms of diabetic retinopathy were examined prospectively in a group of 153 patients with long-standing insulin-dependent diabetes mellitus. During a 4-yr follow-up study, 34 individuals progressed to preproliferative and proliferative retinopathy. The risk of progression to severe forms of diabetic retinopathy was determined by the degree of background diabetic retinopathy and several systemic factors. It increased steeply with hemoglobin A1c, declined proportionally with increasing age, and was dramatically different in patients with diastolic blood pressure below versus above 70 mmHg. Although the mechanisms of action of these systemic factors are unclear, the findings emphasize the multifactorial nature of the pathogenesis of severe forms of eye lesions.
Add to CiteULike CiteULike   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 IOVSHome page
J. A. Phipps, J. L. Wilkinson-Berka, and E. L. Fletcher
Retinal Dysfunction in Diabetic Ren-2 Rats Is Ameliorated by Treatment with Valsartan but Not Atenolol
Invest. Ophthalmol. Vis. Sci., February 1, 2007; 48(2): 927 - 934.
[Abstract] [Full Text] [PDF]

Home page
 IOVSHome page
S. Satofuka, A. Ichihara, N. Nagai, T. Koto, H. Shinoda, K. Noda, Y. Ozawa, M. Inoue, K. Tsubota, H. Itoh, et al.
Role of Nonproteolytically Activated Prorenin in Pathologic, but Not Physiologic, Retinal Neovascularization
Invest. Ophthalmol. Vis. Sci., January 1, 2007; 48(1): 422 - 429.
[Abstract] [Full Text] [PDF]

Home page
 Arch OphthalmolHome page
M. S. Roy and M. Affouf
Six-year progression of retinopathy and associated risk factors in african american patients with type 1 diabetes mellitus: the new jersey 725.
Arch Ophthalmol, September 1, 2006; 124(9): 1297 - 1306.
[Abstract] [Full Text] [PDF]

Home page
 Diabetes CareHome page
D. M. Maahs, G. L. Kinney, P. Wadwa, J. K. Snell-Bergeon, D. Dabelea, J. Hokanson, J. Ehrlich, S. Garg, R. H. Eckel, and M. J. Rewers
Hypertension Prevalence, Awareness, Treatment, and Control in an Adult Type 1 Diabetes Population and a Comparable General Population
Diabetes Care, February 1, 2005; 28(2): 301 - 306.
[Abstract] [Full Text] [PDF]

Home page
 Journal of Renin-Angiotensin-Aldosterone SystemHome page
L. Poulsen
Blood pressure and cardiac autonomic function in relation to risk factors and treatment perspectives in Type 1 diabetes
Journal of Renin-Angiotensin-Aldosterone System, December 1, 2002; 3(4): 222 - 242.
[Abstract] [PDF]

Home page
 Diabetes CareHome page
C. Arauz-Pacheco, M. A. Parrott, and P. Raskin
The Treatment of Hypertension in Adult Patients With Diabetes
Diabetes Care, January 1, 2002; 25(1): 134 - 147.
[Full Text] [PDF]

Home page
 British Journal of Diabetes & Vascular DiseaseHome page
V. Patel, S. Sailesh, S. Panja, and E. Kohner
Retinal perfusion pressure and pulse pressure: clinical parameters predicting progression to sight-threatening diabetic retinopathy
The British Journal of Diabetes & Vascular Disease, January 1, 2001; 1(1): 80 - 87.
[Abstract] [PDF]

Home page
 IOVSHome page
A. Demaine, D. Cross, and A. Millward
Polymorphisms of the Aldose Reductase Gene and Susceptibility to Retinopathy in Type 1 Diabetes Mellitus
Invest. Ophthalmol. Vis. Sci., December 1, 2000; 41(13): 4064 - 4068.
[Abstract] [Full Text]

Home page
 Br. J. Ophthalmol.Home page
O Arend, M Rüffer, and A Remky
Macular circulation in patients with diabetes mellitus with and without arterial hypertension
Br. J. Ophthalmol., December 1, 2000; 84(12): 1392 - 1396.
[Abstract] [Full Text]

Home page
 Br. J. Ophthalmol.Home page
J T GILLOW, J M GIBSON, and P M DODSON
Hypertension and diabetic retinopathy---what's the story?
Br. J. Ophthalmol., September 1, 1999; 83(9): 1083 - 1087.
[Full Text]

Home page
 Arterioscler. Thromb. Vasc. Bio.Home page
S. Lehto, T. Ronnemaa, K. Pyorala, and M. Laakso
Poor Glycemic Control Predicts Coronary Heart Disease Events in Patients With Type 1 Diabetes Without Nephropathy
Arterioscler. Thromb. Vasc. Biol., April 1, 1999; 19(4): 1014 - 1019.
[Abstract] [Full Text] [PDF]

Home page
 Br. J. Ophthalmol.Home page
O. A W E. Haddad and M. K. Saad
Prevalence and risk factors for diabetic retinopathy among Omani diabetics
Br. J. Ophthalmol., August 1, 1998; 82(8): 901 - 906.
[Abstract] [Full Text]

Home page
 NEJMHome page
J. H. Warram, J. E. Manson, and A. S. Krolewski
Glycosylated Hemoglobin and the Risk of Retinopathy in Insulin-Dependent Diabetes Mellitus
N. Engl. J. Med., May 11, 1995; 332(19): 1305 - 1306.
[Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Diabetes Diabetes Care Clinical Diabetes Diabetes Spectrum
Copyright © 1989 by the American Diabetes Association.