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Diabetes, Vol 39, Issue 7 858-864, Copyright © 1990 by American Diabetes Association
Secular trends in incidence of childhood IDDM in 10 countries. Diabetes Epidemiology Research International Group
Standardized childhood insulin-dependent diabetes mellitus (IDDM) incidence
data were collected from 21 ethnic groups in 10 countries to evaluate
temporal trends in the disease between 1966 and 1986. Population-based
registries contributed information concerning periods from 6 to 21 yr. The
incidence rates were modeled with Poisson regression. For the past 2
decades, a linear increase in IDDM risk for people less than 15 yr of age
has been observed in most of Europe and the Western Pacific but not in
North America. The temporal variation did not appear to differ
significantly by age or sex in most locations. The observed pattern of
temporal variation suggests that a proportion of diabetes in childhood may
be caused by a potentially preventable environmental factor.

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Copyright © 1990 by the American Diabetes Association.
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