Diabetes, Vol 40, Issue 7 796-799, Copyright © 1991 by American Diabetes Association

ARTICLES

Risk factors for NIDDM in white population. Paris prospective study

MA Charles, A Fontbonne, N Thibult, JM Warnet, GE Rosselin and E Eschwege
Institut National de la Sante et de la Recherche Medicale (INSERM) U, Villejuif, France.

Risk factors for non-insulin-dependent diabetes mellitus (NIDDM) were assessed in a population of 5042 middle-aged white men, initially nondiabetic, who were followed 3 yr. The subjects were participants in the Paris Prospective Study I. Sixty-three subjects developed diabetes during the follow-up. Plasma glucose concentration in the years before the occurrence of the disease was a major risk factor. Subjects with normal glucose tolerance but elevated fasting plasma glucose exhibited a similar risk of developing NIDDM as did subjects classified as having impaired glucose tolerance on the basis of 2-h postload glucose. In a multiple logistic regression, a high fasting plasma insulin concentration and a low 2-h plasma insulin concentration after a glucose load in association with a high body mass index were independent predictors of conversion to NIDDM from impaired glucose tolerance. Previously, this result had been found only in Nauruans, Pima Indians, and Japanese. This demonstrates for the first time in a white population that a high fasting and low 2-h insulin concentration is predictive of conversion to NIDDM from impaired glucose tolerance.
CiteULike    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				R. D. Bloom and M. F. Crutchlow New-Onset Diabetes Mellitus in the Kidney Recipient: Diagnosis and Management Strategies Clin. J. Am. Soc. Nephrol., March 1, 2008; 3(Supplement_2): S38 - S48. [Abstract] [Full Text] [PDF]

				J. E. Shaw, P. Z. Zimmet, and K. G. M.M. Alberti Point: Impaired Fasting Glucose: The Case for the New American Diabetes Association Criterion Diabetes Care, May 1, 2006; 29(5): 1170 - 1172. [Full Text] [PDF]

				A.-M. Salmasi and M. Dancy The Glucose Tolerance Test, But Not HbA 1c, Remains the Gold Standard in Identifying Unrecognized Diabetes Mellitus and Impaired Glucose Tolerance in Hypertensive Subjects Angiology, September 1, 2005; 56(5): 571 - 579. [Abstract] [PDF]

				G. Levantesi, A. Macchia, R. Marfisi, M. G. Franzosi, A. P. Maggioni, G. L. Nicolosi, C. Schweiger, L. Tavazzi, G. Tognoni, F. Valagussa, et al. Metabolic Syndrome and Risk of Cardiovascular Events After Myocardial Infarction J. Am. Coll. Cardiol., July 19, 2005; 46(2): 277 - 283. [Abstract] [Full Text] [PDF]

				J. A. Luchsinger, M.-X. Tang, S. Shea, and R. Mayeux Hyperinsulinemia and risk of Alzheimer disease Neurology, October 12, 2004; 63(7): 1187 - 1192. [Abstract] [Full Text] [PDF]

				M.-E. Piche, J.-F. Arcand-Bosse, J.-P. Despres, L. Perusse, S. Lemieux, and S. J. Weisnagel What is a Normal Glucose Value?: Differences in indexes of plasma glucose homeostasis in subjects with normal fasting glucose Diabetes Care, October 1, 2004; 27(10): 2470 - 2477. [Abstract] [Full Text] [PDF]

				N. Abate, M. Chandalia, P. G. Snell, and S. M. Grundy Adipose Tissue Metabolites and Insulin Resistance in Nondiabetic Asian Indian Men J. Clin. Endocrinol. Metab., June 1, 2004; 89(6): 2750 - 2755. [Abstract] [Full Text] [PDF]

				J. B. Meigs, K. Williams, L. M. Sullivan, K. J. Hunt, S. M. Haffner, M. P. Stern, C. Gonzalez Villalpando, J. S. Perhanidis, D. M. Nathan, R. B. D'Agostino Jr, et al. Using Metabolic Syndrome Traits for Efficient Detection of Impaired Glucose Tolerance Diabetes Care, June 1, 2004; 27(6): 1417 - 1426. [Abstract] [Full Text] [PDF]

				B. Zethelius, C. N. Hales, H. O. Lithell, and C. Berne Insulin Resistance, Impaired Early Insulin Response, and Insulin Propeptides as Predictors of the Development of Type 2 Diabetes: A population-based, 7-year follow-up study in 70-year-old men Diabetes Care, June 1, 2004; 27(6): 1433 - 1438. [Abstract] [Full Text] [PDF]

				B. V. de Courten, C. Weyer, N. Stefan, M. Horton, A. DelParigi, P. Havel, C. Bogardus, and P. A. Tataranni Parasympathetic Blockade Attenuates Augmented Pancreatic Polypeptide But Not Insulin Secretion in Pima Indians Diabetes, March 1, 2004; 53(3): 663 - 671. [Abstract] [Full Text] [PDF]

				E. Ferrannini, M. Nannipieri, K. Williams, C. Gonzales, S. M. Haffner, and M. P. Stern Mode of Onset of Type 2 Diabetes from Normal or Impaired Glucose Tolerance Diabetes, January 1, 2004; 53(1): 160 - 165. [Abstract] [Full Text] [PDF]

				N. Abate, L. Carulli, A. Cabo-Chan Jr., M. Chandalia, P. G. Snell, and S. M. Grundy Genetic Polymorphism PC-1 K121Q and Ethnic Susceptibility to Insulin Resistance J. Clin. Endocrinol. Metab., December 1, 2003; 88(12): 5927 - 5934. [Abstract] [Full Text] [PDF]

				P. Blackburn, B. Lamarche, C. Couillard, A. Pascot, A. Tremblay, J. Bergeron, I. Lemieux, and J.-P. Despres Contribution of Visceral Adiposity to the Exaggerated Postprandial Lipemia of Men With Impaired Glucose Tolerance Diabetes Care, December 1, 2003; 26(12): 3303 - 3309. [Abstract] [Full Text] [PDF]

				J. P. Burke, K. Williams, K.M. V. Narayan, C. Leibson, S. M. Haffner, and M. P. Stern A Population Perspective on Diabetes Prevention: Whom should we target for preventing weight gain? Diabetes Care, July 1, 2003; 26(7): 1999 - 2004. [Abstract] [Full Text] [PDF]

				J. B. Meigs, D. C. Muller, D. M. Nathan, D. R. Blake, and R. Andres The Natural History of Progression From Normal Glucose Tolerance to Type 2 Diabetes in the Baltimore Longitudinal Study of Aging Diabetes, June 1, 2003; 52(6): 1475 - 1484. [Abstract] [Full Text] [PDF]

				M. Hanefeld, C. Koehler, K. Fuecker, E. Henkel, F. Schaper, and T. Temelkova-Kurktschiev Insulin Secretion and Insulin Sensitivity Pattern Is Different in Isolated Impaired Glucose Tolerance and Impaired Fasting Glucose: The Risk Factor in Impaired Glucose Tolerance for Atherosclerosis and Diabetes Study Diabetes Care, March 1, 2003; 26(3): 868 - 874. [Abstract] [Full Text] [PDF]

				Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus Diabetes Care, January 1, 2003; 26(90001): s5 - 20. [Full Text] [PDF]

				M. A Pereira, D. R Jacobs Jr, J. J Pins, S. K Raatz, M. D Gross, J. L Slavin, and E. R Seaquist Effect of whole grains on insulin sensitivity in overweight hyperinsulinemic adults Am. J. Clinical Nutrition, May 1, 2002; 75(5): 848 - 855. [Abstract] [Full Text] [PDF]

				C. M. Lindgren, E. Widen, T. Tuomi, H. Li, P. Almgren, T. Kanninen, O. Melander, J. Weng, M. Lehto, and L. C. Groop Contribution of Known and Unknown Susceptibility Genes to Early-Onset Diabetes in Scandinavia: Evidence for Heterogeneity Diabetes, May 1, 2002; 51(5): 1609 - 1617. [Abstract] [Full Text] [PDF]

				A. Verrotti, F. Basciani, M. De Simone, D. Trotta, G. Morgese, and F. Chiarelli Insulin Resistance in Epileptic Girls Who Gain Weight After Therapy With Valproic Acid J Child Neurol, April 1, 2002; 17(4): 265 - 268. [Abstract] [PDF]

				A. von Eckardstein, H. Schulte, and G. Assmann Risk for Diabetes Mellitus in Middle-Aged Caucasian Male Participants of the PROCAM Study: Implications for the Definition of Impaired Fasting Glucose by the American Diabetes Association J. Clin. Endocrinol. Metab., September 1, 2000; 85(9): 3101 - 3108. [Abstract] [Full Text]

				F. L. Brancati, N.-Y. Wang, L. A. Mead, K.-Y. Liang, and M. J. Klag Body Weight Patterns From 20 to 49 Years of Age and Subsequent Risk for Diabetes Mellitus: The Johns Hopkins Precursors Study Arch Intern Med, May 10, 1999; 159(9): 957 - 963. [Abstract] [Full Text] [PDF]

				H. E Resnick, T. B Harris, T. Harris, D. Cook, F. P Cappuccio, M. Davies, K Wiener, N B Roberts, O. Famuyiwa, K. Borch-Johnsen, et al. New diagnostic criteria for diabetes mellitus BMJ, February 20, 1999; 318(7182): 531 - 531. [Full Text]

				M. Wei, L. W. Gibbons, T. L. Mitchell, J. B. Kampert, C. D. Lee, and S. N. Blair The Association between Cardiorespiratory Fitness and Impaired Fasting Glucose and Type 2 Diabetes Mellitus in Men Ann Intern Med, January 19, 1999; 130(2): 89 - 96. [Abstract] [Full Text] [PDF]

				E. Ferrannini Insulin Resistance versus Insulin Deficiency in Non-Insulin-Dependent Diabetes Mellitus: Problems and Prospects Endocr. Rev., August 1, 1998; 19(4): 477 - 490. [Abstract] [Full Text] [PDF]

				J. E. Gerich The Genetic Basis of Type 2 Diabetes Mellitus: Impaired Insulin Secretion versus Impaired Insulin Sensitivity Endocr. Rev., August 1, 1998; 19(4): 491 - 503. [Abstract] [Full Text] [PDF]

				M. P. Stern Do Non-Insulin-dependent Diabetes Mellitus and Cardiovascular Disease Share Common Antecedents? Ann Intern Med, January 1, 1996; 124(1_Part_2): 110 - 116. [Abstract] [Full Text]

				S. Lillioja, D. M. Mott, M. Spraul, R. Ferraro, J. E. Foley, E. Ravussin, W. C. Knowler, P. H. Bennett, and C. Bogardus Insulin Resistance and Insulin Secretory Dysfunction as Precursors of Non-Insulin-Dependent Diabetes Mellitus: Prospective Studies of Pima Indians N. Engl. J. Med., December 30, 1993; 329(27): 1988 - 1992. [Abstract] [Full Text]