Online-Only Appendix

Files in this Data Supplement:

• Supplemental Figure 1. F4/80 immunohistochemistry (brown stain) of (eAT) at DIO week 16 reveals F4/80- cells in the interstitium between F4/80+ crown like structures
• Supplemental Figure 2. Morphometric parameters and MÖ marker gene expression in inguinal subcutaneous (iAT) during DIO.
• Supplemental Figure 3. Changes in levels of circulating adipokines over the DIO time course.
• Supplemental Figure 4. Levels of non-esterified free fatty acids (NEFAs) in serum of high fat-fed mice during the DIO time course.
• Supplemental Figure 5. Obesity-associated adipocyte death and CD11c gene expression in retroperitoneal and mesenteric fat compared to inguinal subcutaneous and epidiymal AT.
• Supplemental Figure Legends