Table of Contents

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- J Suga,
- Y Yoshimasa,
- K Yamada,
- Y Yamamoto,
- G Inoue,
- M Okamoto,
- T Hayashi,
- M Shigemoto,
- A Kosaki,
- H Kuzuya,
- and K Nakao
Differential activation of mitogen-activated protein kinase by insulin and epidermal growth factor in 3T3-L1 adipocytes: a possible involvement of PI3-kinase in the activation of the MAP kinase by insulin.
Diabetes May 1997 46:735-741; doi:10.2337/diabetes.46.5.735
- Abstract
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- M Trovati,
- G Anfossi,
- P Massucco,
- L Mattiello,
- C Costamagna,
- V Piretto,
- E Mularoni,
- F Cavalot,
- A Bosia,
- and D Ghigo
Insulin stimulates nitric oxide synthesis in human platelets and, through nitric oxide, increases platelet concentrations of both guanosine-3', 5'-cyclic monophosphate and adenosine-3', 5'-cyclic monophosphate.
Diabetes May 1997 46:742-749; doi:10.2337/diabetes.46.5.742
- Abstract
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- B A O'Brien,
- B V Harmon,
- D P Cameron,
- and D J Allan
Apoptosis is the mode of beta-cell death responsible for the development of IDDM in the nonobese diabetic (NOD) mouse.
Diabetes May 1997 46:750-757; doi:10.2337/diabetes.46.5.750
- Abstract
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- D Elias,
- A Meilin,
- V Ablamunits,
- O S Birk,
- P Carmi,
- S Könen-Waisman,
- and I R Cohen
Hsp60 peptide therapy of NOD mouse diabetes induces a Th2 cytokine burst and downregulates autoimmunity to various beta-cell antigens.
Diabetes May 1997 46:758-764; doi:10.2337/diabetes.46.5.758
- Abstract
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- M Vigneau-Hermellin,
- L Vitali,
- I Tardivel,
- M Rabaud,
- M V Holers,
- and J C Carel
Rejection of islets differing by a single antigen is dependent on donor MHC.
Diabetes May 1997 46:765-769; doi:10.2337/diabetes.46.5.765
- Abstract
Select this article
- M E Baldeón,
- D J Neece,
- D Nandi,
- J J Monaco,
- and H R Gaskins
Interferon-gamma independently activates the MHC class I antigen processing pathway and diminishes glucose responsiveness in pancreatic beta-cell lines.
Diabetes May 1997 46:770-778; doi:10.2337/diabetes.46.5.770
- Abstract
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- P Hutchings,
- P Tonks,
- and A Cooke
Effect of MHC transgene expression on spontaneous insulin autoantibody class switch in nonobese diabetic mice.
Diabetes May 1997 46:779-784; doi:10.2337/diabetes.46.5.779
- Abstract
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- R S Heller,
- T J Kieffer,
- and J F Habener
Insulinotropic glucagon-like peptide I receptor expression in glucagon-producing alpha-cells of the rat endocrine pancreas.
Diabetes May 1997 46:785-791; doi:10.2337/diabetes.46.5.785
- Abstract
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- W G Ding,
- E Renström,
- P Rorsman,
- K Buschard,
- and J Gromada
Glucagon-like peptide I and glucose-dependent insulinotropic polypeptide stimulate Ca2+-induced secretion in rat alpha-cells by a protein kinase A-mediated mechanism.
Diabetes May 1997 46:792-800; doi:10.2337/diabetes.46.5.792
- Abstract
Select this article
- P J Havel and
- B Ahren
Activation of autonomic nerves and the adrenal medulla contributes to increased glucagon secretion during moderate insulin-induced hypoglycemia in women.
Diabetes May 1997 46:801-807; doi:10.2337/diabetes.46.5.801
- Abstract
Select this article
- Y A Hosokawa and
- J L Leahy
Parallel reduction of pancreas insulin content and insulin secretion in 48-h tolbutamide-infused normoglycemic rats.
Diabetes May 1997 46:808-813; doi:10.2337/diabetes.46.5.808
- Abstract
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- P Bottini,
- E Boschetti,
- S Pampanelli,
- M Ciofetta,
- P Del Sindaco,
- L Scionti,
- P Brunetti,
- and G B Bolli
Contribution of autonomic neuropathy to reduced plasma adrenaline responses to hypoglycemia in IDDM: evidence for a nonselective defect.
Diabetes May 1997 46:814-823; doi:10.2337/diabetes.46.5.814
- Abstract
Select this article
- E J Freyse,
- T Becher,
- O El-Hag,
- S Knospe,
- B Göke,
- and U Fischer
Blood glucose lowering and glucagonostatic effects of glucagon-like peptide I in insulin-deprived diabetic dogs.
Diabetes May 1997 46:824-828; doi:10.2337/diabetes.46.5.824
- Abstract
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- M Thomas,
- R S Sherwin,
- J Murphy,
- and D Kerr
Importance of cerebral blood flow to the recognition of and physiological responses to hypoglycemia.
Diabetes May 1997 46:829-833; doi:10.2337/diabetes.46.5.829
- Abstract
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- N F van Det,
- N A Verhagen,
- J T Tamsma,
- J H Berden,
- J A Bruijn,
- M R Daha,
- and F J van der Woude
Regulation of glomerular epithelial cell production of fibronectin and transforming growth factor-beta by high glucose, not by angiotensin II.
Diabetes May 1997 46:834-840; doi:10.2337/diabetes.46.5.834
- Abstract
Select this article
- J Gagné,
- M Milot,
- S Gélinas,
- A Lahsaïni,
- F Trudeau,
- M G Martinoli,
- and G Massicotte
Binding properties of glutamate receptors in streptozotocin-induced diabetes in rats.
Diabetes May 1997 46:841-846; doi:10.2337/diabetes.46.5.841
- Abstract
Select this article
- M Haneda,
- S Araki,
- M Togawa,
- T Sugimoto,
- M Isono,
- and R Kikkawa
Mitogen-activated protein kinase cascade is activated in glomeruli of diabetic rats and glomerular mesangial cells cultured under high glucose conditions.
Diabetes May 1997 46:847-853; doi:10.2337/diabetes.46.5.847
- Abstract
Select this article
- K Sharma,
- F N Ziyadeh,
- B Alzahabi,
- T A McGowan,
- S Kapoor,
- B R Kurnik,
- P B Kurnik,
- and L S Weisberg
Increased renal production of transforming growth factor-beta1 in patients with type II diabetes.
Diabetes May 1997 46:854-859; doi:10.2337/diabetes.46.5.854
- Abstract
Select this article
- M C Alessi,
- F Peiretti,
- P Morange,
- M Henry,
- G Nalbone,
- and I Juhan-Vague
Production of plasminogen activator inhibitor 1 by human adipose tissue: possible link between visceral fat accumulation and vascular disease.
Diabetes May 1997 46:860-867; doi:10.2337/diabetes.46.5.860
- Abstract
Select this article
- C Catalano,
- E Muscelli,
- A Quiñones Galvan,
- S Baldi,
- A Masoni,
- I Gibb,
- O Torffvit,
- G Seghieri,
- and E Ferrannini
Effect of insulin on systemic and renal handling of albumin in nondiabetic and NIDDM subjects.
Diabetes May 1997 46:868-875; doi:10.2337/diabetes.46.5.868
- Abstract
Select this article
- L Ji,
- M Malecki,
- J H Warram,
- Y Yang,
- S S Rich,
- and A S Krolewski
New susceptibility locus for NIDDM is localized to human chromosome 20q.
Diabetes May 1997 46:876-881; doi:10.2337/diabetes.46.5.876
- Abstract
Select this article
- D W Bowden,
- M Sale,
- T D Howard,
- A Qadri,
- B J Spray,
- C B Rothschild,
- G Akots,
- S S Rich,
- and B I Freedman
Linkage of genetic markers on human chromosomes 20 and 12 to NIDDM in Caucasian sib pairs with a history of diabetic nephropathy.
Diabetes May 1997 46:882-886; doi:10.2337/diabetes.46.5.882
- Abstract
Select this article
- M Yoshioka,
- T Kayo,
- T Ikeda,
- and A Koizumi
A novel locus, Mody4, distal to D7Mit189 on chromosome 7 determines early-onset NIDDM in nonobese C57BL/6 (Akita) mutant mice.
Diabetes May 1997 46:887-894; doi:10.2337/diabetes.46.5.887
- Abstract
Select this article
- S Nakamura,
- Z Makita,
- S Ishikawa,
- K Yasumura,
- W Fujii,
- K Yanagisawa,
- T Kawata,
- and T Koike
Progression of nephropathy in spontaneous diabetic rats is prevented by OPB-9195, a novel inhibitor of advanced glycation.
Diabetes May 1997 46:895-899; doi:10.2337/diabetes.46.5.895
- Abstract
Select this article
- R E Gimeno,
- M Dembski,
- X Weng,
- N Deng,
- A W Shyjan,
- C J Gimeno,
- F Iris,
- S J Ellis,
- E A Woolf,
- and L A Tartaglia
Cloning and characterization of an uncoupling protein homolog: a potential molecular mediator of human thermogenesis.
Diabetes May 1997 46:900-906; doi:10.2337/diabetes.46.5.900
- Abstract
Select this article
- W L Suarez-Pinzon,
- C Szabó,
- and A Rabinovitch
Development of autoimmune diabetes in NOD mice is associated with the formation of peroxynitrite in pancreatic islet beta-cells.
Diabetes May 1997 46:907-911; doi:10.2337/diabetes.46.5.907
- Abstract
Select this article
- S A Urhammer,
- M Fridberg,
- T Hansen,
- S K Rasmussen,
- A M Møller,
- J O Clausen,
- and O Pedersen
A prevalent amino acid polymorphism at codon 98 in the hepatocyte nuclear factor-1alpha gene is associated with reduced serum C-peptide and insulin responses to an oral glucose challenge.
Diabetes May 1997 46:912-916; doi:10.2337/diabetes.46.5.912
- Abstract
Select this article
- E Sivan,
- W M Lin,
- C J Homko,
- E A Reece,
- and G Boden
Leptin is present in human cord blood.
Diabetes May 1997 46:917-919; doi:10.2337/diabetes.46.5.917
- Abstract
Select this article
- P Liang,
- V Hughes,
- and N K Fukagawa
Increased prevalence of mitochondrial DNA deletions in skeletal muscle of older individuals with impaired glucose tolerance: possible marker of glycemic stress.
Diabetes May 1997 46:920-923; doi:10.2337/diabetes.46.5.920
- Abstract

Differential activation of mitogen-activated protein kinase by insulin and epidermal growth factor in 3T3-L1 adipocytes: a possible involvement of PI3-kinase in the activation of the MAP kinase by insulin.

Insulin stimulates nitric oxide synthesis in human platelets and, through nitric oxide, increases platelet concentrations of both guanosine-3', 5'-cyclic monophosphate and adenosine-3', 5'-cyclic monophosphate.

Apoptosis is the mode of beta-cell death responsible for the development of IDDM in the nonobese diabetic (NOD) mouse.

Hsp60 peptide therapy of NOD mouse diabetes induces a Th2 cytokine burst and downregulates autoimmunity to various beta-cell antigens.

Rejection of islets differing by a single antigen is dependent on donor MHC.

Interferon-gamma independently activates the MHC class I antigen processing pathway and diminishes glucose responsiveness in pancreatic beta-cell lines.

Effect of MHC transgene expression on spontaneous insulin autoantibody class switch in nonobese diabetic mice.

Insulinotropic glucagon-like peptide I receptor expression in glucagon-producing alpha-cells of the rat endocrine pancreas.

Glucagon-like peptide I and glucose-dependent insulinotropic polypeptide stimulate Ca2+-induced secretion in rat alpha-cells by a protein kinase A-mediated mechanism.

Activation of autonomic nerves and the adrenal medulla contributes to increased glucagon secretion during moderate insulin-induced hypoglycemia in women.

Parallel reduction of pancreas insulin content and insulin secretion in 48-h tolbutamide-infused normoglycemic rats.

Contribution of autonomic neuropathy to reduced plasma adrenaline responses to hypoglycemia in IDDM: evidence for a nonselective defect.

Blood glucose lowering and glucagonostatic effects of glucagon-like peptide I in insulin-deprived diabetic dogs.

Importance of cerebral blood flow to the recognition of and physiological responses to hypoglycemia.

Regulation of glomerular epithelial cell production of fibronectin and transforming growth factor-beta by high glucose, not by angiotensin II.

Binding properties of glutamate receptors in streptozotocin-induced diabetes in rats.

Mitogen-activated protein kinase cascade is activated in glomeruli of diabetic rats and glomerular mesangial cells cultured under high glucose conditions.

Increased renal production of transforming growth factor-beta1 in patients with type II diabetes.

Production of plasminogen activator inhibitor 1 by human adipose tissue: possible link between visceral fat accumulation and vascular disease.

Effect of insulin on systemic and renal handling of albumin in nondiabetic and NIDDM subjects.

New susceptibility locus for NIDDM is localized to human chromosome 20q.

Linkage of genetic markers on human chromosomes 20 and 12 to NIDDM in Caucasian sib pairs with a history of diabetic nephropathy.

A novel locus, Mody4, distal to D7Mit189 on chromosome 7 determines early-onset NIDDM in nonobese C57BL/6 (Akita) mutant mice.

Progression of nephropathy in spontaneous diabetic rats is prevented by OPB-9195, a novel inhibitor of advanced glycation.

Cloning and characterization of an uncoupling protein homolog: a potential molecular mediator of human thermogenesis.

Development of autoimmune diabetes in NOD mice is associated with the formation of peroxynitrite in pancreatic islet beta-cells.

A prevalent amino acid polymorphism at codon 98 in the hepatocyte nuclear factor-1alpha gene is associated with reduced serum C-peptide and insulin responses to an oral glucose challenge.

Leptin is present in human cord blood.

Increased prevalence of mitochondrial DNA deletions in skeletal muscle of older individuals with impaired glucose tolerance: possible marker of glycemic stress.

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