Table of Contents

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- N Giannoukakis,
- W A Rudert,
- P D Robbins,
- and M Trucco
Targeting autoimmune diabetes with gene therapy.
Diabetes November 1999 48:2107-2121; doi:10.2337/diabetes.48.11.2107
- Abstract
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- A M Valverde,
- C R Kahn,
- and M Benito
Insulin signaling in insulin receptor substrate (IRS)-1-deficient brown adipocytes: requirement of IRS-1 for lipid synthesis.
Diabetes November 1999 48:2122-2131; doi:10.2337/diabetes.48.11.2122
- Abstract
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- X J Cai,
- P S Widdowson,
- J Harrold,
- S Wilson,
- R E Buckingham,
- J R Arch,
- M Tadayyon,
- J C Clapham,
- J Wilding,
- and G Williams
Hypothalamic orexin expression: modulation by blood glucose and feeding.
Diabetes November 1999 48:2132-2137; doi:10.2337/diabetes.48.11.2132
- Abstract
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- A M Martin,
- M N Maxson,
- J Leif,
- J P Mordes,
- D L Greiner,
- and E P Blankenhorn
Diabetes-prone and diabetes-resistant BB rats share a common major diabetes susceptibility locus, iddm4: additional evidence for a "universal autoimmunity locus" on rat chromosome 4.
Diabetes November 1999 48:2138-2144; doi:10.2337/diabetes.48.11.2138
- Abstract
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- J J Couper,
- C Steele,
- S Beresford,
- T Powell,
- K McCaul,
- A Pollard,
- S Gellert,
- B Tait,
- L C Harrison,
- and P G Colman
Lack of association between duration of breast-feeding or introduction of cow's milk and development of islet autoimmunity.
Diabetes November 1999 48:2145-2149; doi:10.2337/diabetes.48.11.2145
- Abstract
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- C Ploix,
- I Bergerot,
- A Durand,
- C Czerkinsky,
- J Holmgren,
- and C Thivolet
Oral administration of cholera toxin B-insulin conjugates protects NOD mice from autoimmune diabetes by inducing CD4+ regulatory T-cells.
Diabetes November 1999 48:2150-2156; doi:10.2337/diabetes.48.11.2150
- Abstract
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- V L Heath,
- P Hutchings,
- D J Fowell,
- A Cooke,
- and D W Mason
Peptides derived from murine insulin are diabetogenic in both rats and mice, but the disease-inducing epitopes are different: evidence against a common environmental cross-reactivity in the pathogenicity of type 1 diabetes.
Diabetes November 1999 48:2157-2165; doi:10.2337/diabetes.48.11.2157
- Abstract
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- M J Redondo,
- P A Gottlieb,
- T Motheral,
- C Mulgrew,
- M Rewers,
- S Babu,
- E Stephens,
- D R Wegmann,
- and G S Eisenbarth
Heterophile anti-mouse immunoglobulin antibodies may interfere with cytokine measurements in patients with HLA alleles protective for type 1A diabetes.
Diabetes November 1999 48:2166-2170; doi:10.2337/diabetes.48.11.2166
- Abstract
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- C R Poulsen,
- K Bokvist,
- H L Olsen,
- M Høy,
- K Capito,
- P Gilon,
- and J Gromada
Multiple sites of purinergic control of insulin secretion in mouse pancreatic beta-cells.
Diabetes November 1999 48:2171-2181; doi:10.2337/diabetes.48.11.2171
- Abstract
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- G Boden,
- X Chen,
- and M Polansky
Disruption of circadian insulin secretion is associated with reduced glucose uptake in first-degree relatives of patients with type 2 diabetes.
Diabetes November 1999 48:2182-2188; doi:10.2337/diabetes.48.11.2182
- Abstract
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- C E Mathews and
- E H Leiter
Resistance of ALR/Lt islets to free radical-mediated diabetogenic stress is inherited as a dominant trait.
Diabetes November 1999 48:2189-2196; doi:10.2337/diabetes.48.11.2189
- Abstract
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- C Weyer,
- C Bogardus,
- and R E Pratley
Metabolic characteristics of individuals with impaired fasting glucose and/or impaired glucose tolerance.
Diabetes November 1999 48:2197-2203; doi:10.2337/diabetes.48.11.2197
- Abstract
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- P Grasso,
- D W White,
- L A Tartaglia,
- M C Leinung,
- and D W Lee
Inhibitory effects of leptin-related synthetic peptide 116-130 on food intake and body weight gain in female C57BL/6J ob/ob mice may not be mediated by peptide activation of the long isoform of the leptin receptor.
Diabetes November 1999 48:2204-2209; doi:10.2337/diabetes.48.11.2204
- Abstract
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- R V Dvorak,
- W F DeNino,
- P A Ades,
- and E T Poehlman
Phenotypic characteristics associated with insulin resistance in metabolically obese but normal-weight young women.
Diabetes November 1999 48:2210-2214; doi:10.2337/diabetes.48.11.2210
- Abstract
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- M Portero-Otín,
- R Pamplona,
- M C Ruiz,
- E Cabiscol,
- J Prat,
- and M J Bellmunt
Diabetes induces an impairment in the proteolytic activity against oxidized proteins and a heterogeneous effect in nonenzymatic protein modifications in the cytosol of rat liver and kidney.
Diabetes November 1999 48:2215-2220; doi:10.2337/diabetes.48.11.2215
- Abstract
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- R A Rabini,
- N Cester,
- R Staffolani,
- E Salvolini,
- N Moretti,
- A Vignini,
- D Fumelli,
- and L Mazzanti
Modifications induced by LDL from type 1 diabetic patients on endothelial cells obtained from human umbilical vein.
Diabetes November 1999 48:2221-2228; doi:10.2337/diabetes.48.11.2221
- Abstract
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- M E Cooper,
- D Vranes,
- S Youssef,
- S A Stacker,
- A J Cox,
- B Rizkalla,
- D J Casley,
- L A Bach,
- D J Kelly,
- and R E Gilbert
Increased renal expression of vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 in experimental diabetes.
Diabetes November 1999 48:2229-2239; doi:10.2337/diabetes.48.11.2229
- Abstract
- Full Text (PDF)
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- K Amri,
- N Freund,
- J Vilar,
- C Merlet-Bénichou,
- and M Lelièvre-Pégorier
Adverse effects of hyperglycemia on kidney development in rats: in vivo and in vitro studies.
Diabetes November 1999 48:2240-2245; doi:10.2337/diabetes.48.11.2240
- Abstract
- Full Text (PDF)
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- A Bektas,
- M E Suprenant,
- L T Wogan,
- N Plengvidhya,
- S S Rich,
- J H Warram,
- A S Krolewski,
- and A Doria
Evidence of a novel type 2 diabetes locus 50 cM centromeric to NIDDM2 on chromosome 12q.
Diabetes November 1999 48:2246-2251; doi:10.2337/diabetes.48.11.2246
- Abstract
- Full Text (PDF)

Diabetes

Targeting autoimmune diabetes with gene therapy.

Insulin signaling in insulin receptor substrate (IRS)-1-deficient brown adipocytes: requirement of IRS-1 for lipid synthesis.

Hypothalamic orexin expression: modulation by blood glucose and feeding.

Diabetes-prone and diabetes-resistant BB rats share a common major diabetes susceptibility locus, iddm4: additional evidence for a "universal autoimmunity locus" on rat chromosome 4.

Lack of association between duration of breast-feeding or introduction of cow's milk and development of islet autoimmunity.

Oral administration of cholera toxin B-insulin conjugates protects NOD mice from autoimmune diabetes by inducing CD4+ regulatory T-cells.

Peptides derived from murine insulin are diabetogenic in both rats and mice, but the disease-inducing epitopes are different: evidence against a common environmental cross-reactivity in the pathogenicity of type 1 diabetes.

Heterophile anti-mouse immunoglobulin antibodies may interfere with cytokine measurements in patients with HLA alleles protective for type 1A diabetes.

Multiple sites of purinergic control of insulin secretion in mouse pancreatic beta-cells.

Disruption of circadian insulin secretion is associated with reduced glucose uptake in first-degree relatives of patients with type 2 diabetes.

Resistance of ALR/Lt islets to free radical-mediated diabetogenic stress is inherited as a dominant trait.

Metabolic characteristics of individuals with impaired fasting glucose and/or impaired glucose tolerance.

Inhibitory effects of leptin-related synthetic peptide 116-130 on food intake and body weight gain in female C57BL/6J ob/ob mice may not be mediated by peptide activation of the long isoform of the leptin receptor.

Phenotypic characteristics associated with insulin resistance in metabolically obese but normal-weight young women.

Diabetes induces an impairment in the proteolytic activity against oxidized proteins and a heterogeneous effect in nonenzymatic protein modifications in the cytosol of rat liver and kidney.

Modifications induced by LDL from type 1 diabetic patients on endothelial cells obtained from human umbilical vein.

Increased renal expression of vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 in experimental diabetes.

Adverse effects of hyperglycemia on kidney development in rats: in vivo and in vitro studies.

Evidence of a novel type 2 diabetes locus 50 cM centromeric to NIDDM2 on chromosome 12q.

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