Table of Contents

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- J A Hamilton and
- F Kamp
How are free fatty acids transported in membranes? Is it by proteins or by free diffusion through the lipids?
Diabetes December 1999 48:2255-2269; doi:10.2337/diabetes.48.12.2255
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- G Xu,
- D A Stoffers,
- J F Habener,
- and S Bonner-Weir
Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats.
Diabetes December 1999 48:2270-2276; doi:10.2337/diabetes.48.12.2270
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- M Federici,
- A Giaccari,
- M L Hribal,
- B Giovannone,
- D Lauro,
- L Morviducci,
- L Pastore,
- G Tamburrano,
- R Lauro,
- and G Sesti
Evidence for glucose/hexosamine in vivo regulation of insulin/IGF-I hybrid receptor assembly.
Diabetes December 1999 48:2277-2285; doi:10.2337/diabetes.48.12.2277
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- H Yoshimatsu,
- E Itateyama,
- S Kondou,
- D Tajima,
- K Himeno,
- S Hidaka,
- M Kurokawa,
- and T Sakata
Hypothalamic neuronal histamine as a target of leptin in feeding behavior.
Diabetes December 1999 48:2286-2291; doi:10.2337/diabetes.48.12.2286
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- H Li,
- C Ricordi,
- and L Inverardi
Effects of graft-versus-host reaction on intrahepatic islet transplants.
Diabetes December 1999 48:2292-2299; doi:10.2337/diabetes.48.12.2292
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- M Feili-Hariri,
- X Dong,
- S M Alber,
- S C Watkins,
- R D Salter,
- and P A Morel
Immunotherapy of NOD mice with bone marrow-derived dendritic cells.
Diabetes December 1999 48:2300-2308; doi:10.2337/diabetes.48.12.2300
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- C Pupilli,
- S Giannini,
- P Marchetti,
- R Lupi,
- A Antonelli,
- F Malavasi,
- S Takasawa,
- H Okamoto,
- and E Ferrannini
Autoantibodies to CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) in Caucasian patients with diabetes: effects on insulin release from human islets.
Diabetes December 1999 48:2309-2315; doi:10.2337/diabetes.48.12.2309
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- L Panicot,
- E Mas,
- C Thivolet,
- and D Lombardo
Circulating antibodies against an exocrine pancreatic enzyme in type 1 diabetes.
Diabetes December 1999 48:2316-2323; doi:10.2337/diabetes.48.12.2316
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- K Nielsen,
- A E Karlsen,
- M Deckert,
- O D Madsen,
- P Serup,
- T Mandrup-Poulsen,
- and J Nerup
Beta-cell maturation leads to in vitro sensitivity to cytotoxins.
Diabetes December 1999 48:2324-2332; doi:10.2337/diabetes.48.12.2324
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- F Nicoletti,
- P Zaccone,
- I Conget,
- R Gomis,
- C Möller,
- P L Meroni,
- K Bendtzen,
- W Trepicchio,
- and S Sandler
Early prophylaxis with recombinant human interleukin-11 prevents spontaneous diabetes in NOD mice.
Diabetes December 1999 48:2333-2339; doi:10.2337/diabetes.48.12.2333
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- T Friedman,
- R N Smith,
- R B Colvin,
- and J Iacomini
A critical role for human CD4+ T-cells in rejection of porcine islet cell xenografts.
Diabetes December 1999 48:2340-2348; doi:10.2337/diabetes.48.12.2340
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- J C Chapman,
- N H McClenaghan,
- K E Cosgrove,
- M N Hashmi,
- R M Shepherd,
- A N Giesberts,
- S J White,
- C Ammälä,
- P R Flatt,
- and M J Dunne
ATP-sensitive potassium channels and efaroxan-induced insulin release in the electrofusion-derived BRIN-BD11 beta-cell line.
Diabetes December 1999 48:2349-2357; doi:10.2337/diabetes.48.12.2349
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- J Zhou,
- X Wang,
- M A Pineyro,
- and J M Egan
Glucagon-like peptide 1 and exendin-4 convert pancreatic AR42J cells into glucagon- and insulin-producing cells.
Diabetes December 1999 48:2358-2366; doi:10.2337/diabetes.48.12.2358
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- S Nagamatsu,
- Y Nakamichi,
- C Yamamura,
- S Matsushima,
- T Watanabe,
- S Ozawa,
- H Furukawa,
- and H Ishida
Decreased expression of t-SNARE, syntaxin 1, and SNAP-25 in pancreatic beta-cells is involved in impaired insulin secretion from diabetic GK rat islets: restoration of decreased t-SNARE proteins improves impaired insulin secretion.
Diabetes December 1999 48:2367-2373; doi:10.2337/diabetes.48.12.2367
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- M A Ravier,
- P Gilon,
- and J C Henquin
Oscillations of insulin secretion can be triggered by imposed oscillations of cytoplasmic Ca2+ or metabolism in normal mouse islets.
Diabetes December 1999 48:2374-2382; doi:10.2337/diabetes.48.12.2374
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- J R Wilson,
- T J Biden,
- and R I Ludowyke
Increases in phosphorylation of the myosin II heavy chain, but not regulatory light chains, correlate with insulin secretion in rat pancreatic islets and RINm5F cells.
Diabetes December 1999 48:2383-2389; doi:10.2337/diabetes.48.12.2383
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- I Quesada,
- A Nadal,
- and B Soria
Different effects of tolbutamide and diazoxide in alpha, beta-, and delta-cells within intact islets of Langerhans.
Diabetes December 1999 48:2390-2397; doi:10.2337/diabetes.48.12.2390
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- H Kaneto,
- Y Kajimoto,
- J Miyagawa,
- T Matsuoka,
- Y Fujitani,
- Y Umayahara,
- T Hanafusa,
- Y Matsuzawa,
- Y Yamasaki,
- and M Hori
Beneficial effects of antioxidants in diabetes: possible protection of pancreatic beta-cells against glucose toxicity.
Diabetes December 1999 48:2398-2406; doi:10.2337/diabetes.48.12.2398
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- Y Akimoto,
- L K Kreppel,
- H Hirano,
- and G W Hart
Localization of the O-linked N-acetylglucosamine transferase in rat pancreas.
Diabetes December 1999 48:2407-2413; doi:10.2337/diabetes.48.12.2407
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- J G Yu,
- Y T Kruszynska,
- M I Mulford,
- and J M Olefsky
A comparison of troglitazone and metformin on insulin requirements in euglycemic intensively insulin-treated type 2 diabetic patients.
Diabetes December 1999 48:2414-2421; doi:10.2337/diabetes.48.12.2414
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- A Bavdekar,
- C S Yajnik,
- C H Fall,
- S Bapat,
- A N Pandit,
- V Deshpande,
- S Bhave,
- S D Kellingray,
- and C Joglekar
Insulin resistance syndrome in 8-year-old Indian children: small at birth, big at 8 years, or both?
Diabetes December 1999 48:2422-2429; doi:10.2337/diabetes.48.12.2422
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- T A Buchanan,
- A H Xiang,
- S L Kjos,
- E Trigo,
- W P Lee,
- and R K Peters
Antepartum predictors of the development of type 2 diabetes in Latino women 11-26 months after pregnancies complicated by gestational diabetes.
Diabetes December 1999 48:2430-2436; doi:10.2337/diabetes.48.12.2430
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- K Shinozaki,
- A Kashiwagi,
- Y Nishio,
- T Okamura,
- Y Yoshida,
- M Masada,
- N Toda,
- and R Kikkawa
Abnormal biopterin metabolism is a major cause of impaired endothelium-dependent relaxation through nitric oxide/O2- imbalance in insulin-resistant rat aorta.
Diabetes December 1999 48:2437-2445; doi:10.2337/diabetes.48.12.2437
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- C G Schalkwijk,
- N Ligtvoet,
- H Twaalfhoven,
- A Jager,
- H G Blaauwgeers,
- R O Schlingemann,
- L Tarnow,
- H H Parving,
- C D Stehouwer,
- and V W van Hinsbergh
Amadori albumin in type 1 diabetic patients: correlation with markers of endothelial function, association with diabetic nephropathy, and localization in retinal capillaries.
Diabetes December 1999 48:2446-2453; doi:10.2337/diabetes.48.12.2446
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- E L Fine,
- M Horal,
- T I Chang,
- G Fortin,
- and M R Loeken
Evidence that elevated glucose causes altered gene expression, apoptosis, and neural tube defects in a mouse model of diabetic pregnancy.
Diabetes December 1999 48:2454-2462; doi:10.2337/diabetes.48.12.2454
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- J Galli,
- H Fakhrai-Rad,
- A Kamel,
- C Marcus,
- S Norgren,
- and H Luthman
Pathophysiological and genetic characterization of the major diabetes locus in GK rats.
Diabetes December 1999 48:2463-2470; doi:10.2337/diabetes.48.12.2463
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- N Yokomori,
- M Tawata,
- and T Onaya
A transcriptional repressor regulates mouse GLUT4 gene expression during the differentiation of 3T3-L1 cells.
Diabetes December 1999 48:2471-2474; doi:10.2337/diabetes.48.12.2471
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- T M Frayling,
- M Walker,
- M I McCarthy,
- J C Evans,
- L I Allen,
- S Lynn,
- S Ayres,
- B Millauer,
- C Turner,
- R C Turner,
- M J Sampson,
- G A Hitman,
- S Ellard,
- and A T Hattersley
Parent-offspring trios: a resource to facilitate the identification of type 2 diabetes genes.
Diabetes December 1999 48:2475-2479; doi:10.2337/diabetes.48.12.2475
- Abstract
- Full Text (PDF)

How are free fatty acids transported in membranes? Is it by proteins or by free diffusion through the lipids?

Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats.

Evidence for glucose/hexosamine in vivo regulation of insulin/IGF-I hybrid receptor assembly.

Hypothalamic neuronal histamine as a target of leptin in feeding behavior.

Effects of graft-versus-host reaction on intrahepatic islet transplants.

Immunotherapy of NOD mice with bone marrow-derived dendritic cells.

Autoantibodies to CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) in Caucasian patients with diabetes: effects on insulin release from human islets.

Circulating antibodies against an exocrine pancreatic enzyme in type 1 diabetes.

Beta-cell maturation leads to in vitro sensitivity to cytotoxins.

Early prophylaxis with recombinant human interleukin-11 prevents spontaneous diabetes in NOD mice.

A critical role for human CD4+ T-cells in rejection of porcine islet cell xenografts.

ATP-sensitive potassium channels and efaroxan-induced insulin release in the electrofusion-derived BRIN-BD11 beta-cell line.

Glucagon-like peptide 1 and exendin-4 convert pancreatic AR42J cells into glucagon- and insulin-producing cells.

Decreased expression of t-SNARE, syntaxin 1, and SNAP-25 in pancreatic beta-cells is involved in impaired insulin secretion from diabetic GK rat islets: restoration of decreased t-SNARE proteins improves impaired insulin secretion.

Oscillations of insulin secretion can be triggered by imposed oscillations of cytoplasmic Ca2+ or metabolism in normal mouse islets.

Increases in phosphorylation of the myosin II heavy chain, but not regulatory light chains, correlate with insulin secretion in rat pancreatic islets and RINm5F cells.

Different effects of tolbutamide and diazoxide in alpha, beta-, and delta-cells within intact islets of Langerhans.

Beneficial effects of antioxidants in diabetes: possible protection of pancreatic beta-cells against glucose toxicity.

Localization of the O-linked N-acetylglucosamine transferase in rat pancreas.

A comparison of troglitazone and metformin on insulin requirements in euglycemic intensively insulin-treated type 2 diabetic patients.

Insulin resistance syndrome in 8-year-old Indian children: small at birth, big at 8 years, or both?

Antepartum predictors of the development of type 2 diabetes in Latino women 11-26 months after pregnancies complicated by gestational diabetes.

Abnormal biopterin metabolism is a major cause of impaired endothelium-dependent relaxation through nitric oxide/O2- imbalance in insulin-resistant rat aorta.

Amadori albumin in type 1 diabetic patients: correlation with markers of endothelial function, association with diabetic nephropathy, and localization in retinal capillaries.

Evidence that elevated glucose causes altered gene expression, apoptosis, and neural tube defects in a mouse model of diabetic pregnancy.

Pathophysiological and genetic characterization of the major diabetes locus in GK rats.

A transcriptional repressor regulates mouse GLUT4 gene expression during the differentiation of 3T3-L1 cells.

Parent-offspring trios: a resource to facilitate the identification of type 2 diabetes genes.

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