Table of Contents

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- M Laakso
Hyperglycemia and cardiovascular disease in type 2 diabetes.
Diabetes May 1999 48:937-942; doi:10.2337/diabetes.48.5.937
- Abstract
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- C Meyer,
- J M Dostou,
- and J E Gerich
Role of the human kidney in glucose counterregulation.
Diabetes May 1999 48:943-948; doi:10.2337/diabetes.48.5.943
- Abstract
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- G Biolo,
- B D Williams,
- R Y Fleming,
- and R R Wolfe
Insulin action on muscle protein kinetics and amino acid transport during recovery after resistance exercise.
Diabetes May 1999 48:949-957; doi:10.2337/diabetes.48.5.949
- Abstract
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- B Capaldo,
- A Gastaldelli,
- S Antoniello,
- M Auletta,
- F Pardo,
- D Ciociaro,
- R Guida,
- E Ferrannini,
- and L Saccà
Splanchnic and leg substrate exchange after ingestion of a natural mixed meal in humans.
Diabetes May 1999 48:958-966; doi:10.2337/diabetes.48.5.958
- Abstract
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- T G Markees,
- D V Serreze,
- N E Phillips,
- C H Sorli,
- E J Gordon,
- L D Shultz,
- R J Noelle,
- B A Woda,
- D L Greiner,
- J P Mordes,
- and A A Rossini
NOD mice have a generalized defect in their response to transplantation tolerance induction.
Diabetes May 1999 48:967-974; doi:10.2337/diabetes.48.5.967
- Abstract
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- K E Ellerman and
- A A Like
Islet cell membrane antigens activate diabetogenic CD4+ T-cells in the BB/Wor rat.
Diabetes May 1999 48:975-982; doi:10.2337/diabetes.48.5.975
- Abstract
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- B M Brooks-Worrell,
- R Juneja,
- A Minokadeh,
- C J Greenbaum,
- and J P Palmer
Cellular immune responses to human islet proteins in antibody-positive type 2 diabetic patients.
Diabetes May 1999 48:983-988; doi:10.2337/diabetes.48.5.983
- Abstract
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- S Sreenan,
- A J Pick,
- M Levisetti,
- A C Baldwin,
- W Pugh,
- and K S Polonsky
Increased beta-cell proliferation and reduced mass before diabetes onset in the nonobese diabetic mouse.
Diabetes May 1999 48:989-996; doi:10.2337/diabetes.48.5.989
- Abstract
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- C B Chan,
- R M MacPhail,
- L Sheu,
- M B Wheeler,
- and H Y Gaisano
Beta-cell hypertrophy in fa/fa rats is associated with basal glucose hypersensitivity and reduced SNARE protein expression.
Diabetes May 1999 48:997-1005; doi:10.2337/diabetes.48.5.997
- Abstract
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- H Yajima,
- M Komatsu,
- T Schermerhorn,
- T Aizawa,
- T Kaneko,
- M Nagai,
- G W Sharp,
- and K Hashizume
cAMP enhances insulin secretion by an action on the ATP-sensitive K+ channel-independent pathway of glucose signaling in rat pancreatic islets.
Diabetes May 1999 48:1006-1012; doi:10.2337/diabetes.48.5.1006
- Abstract
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- G M Beattie,
- P Itkin-Ansari,
- V Cirulli,
- G Leibowitz,
- A D Lopez,
- S Bossie,
- M I Mally,
- F Levine,
- and A Hayek
Sustained proliferation of PDX-1+ cells derived from human islets.
Diabetes May 1999 48:1013-1019; doi:10.2337/diabetes.48.5.1013
- Abstract
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- M Y Wang,
- M Shimabukuro,
- Y Lee,
- K Y Trinh,
- J L Chen,
- C B Newgard,
- and R H Unger
Adenovirus-mediated overexpression of uncoupling protein-2 in pancreatic islets of Zucker diabetic rats increases oxidative activity and improves beta-cell function.
Diabetes May 1999 48:1020-1025; doi:10.2337/diabetes.48.5.1020
- Abstract
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- A A Young,
- B R Gedulin,
- S Bhavsar,
- N Bodkin,
- C Jodka,
- B Hansen,
- and M Denaro
Glucose-lowering and insulin-sensitizing actions of exendin-4: studies in obese diabetic (ob/ob, db/db) mice, diabetic fatty Zucker rats, and diabetic rhesus monkeys (Macaca mulatta).
Diabetes May 1999 48:1026-1034; doi:10.2337/diabetes.48.5.1026
- Abstract
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- R Gasa,
- K Y Trinh,
- K Yu,
- T M Wilkie,
- and C B Newgard
Overexpression of G11alpha and isoforms of phospholipase C in islet beta-cells reveals a lack of correlation between inositol phosphate accumulation and insulin secretion.
Diabetes May 1999 48:1035-1044; doi:10.2337/diabetes.48.5.1035
- Abstract
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- H Sandhu,
- S R Wiesenthal,
- P E MacDonald,
- R H McCall,
- V Tchipashvili,
- S Rashid,
- M Satkunarajah,
- D M Irwin,
- Z Q Shi,
- P L Brubaker,
- M B Wheeler,
- M Vranic,
- S Efendic,
- and A Giacca
Glucagon-like peptide 1 increases insulin sensitivity in depancreatized dogs.
Diabetes May 1999 48:1045-1053; doi:10.2337/diabetes.48.5.1045
- Abstract
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- S Nagasaka,
- K Tokuyama,
- I Kusaka,
- H Hayashi,
- K Rokkaku,
- T Nakamura,
- A Kawakami,
- M Higashiyama,
- S Ishikawa,
- and T Saito
Endogenous glucose production and glucose effectiveness in type 2 diabetic subjects derived from stable-labeled minimal model approach.
Diabetes May 1999 48:1054-1060; doi:10.2337/diabetes.48.5.1054
- Abstract
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- T Ishizuka,
- P Klepcyk,
- S Liu,
- L Panko,
- S Liu,
- E M Gibbs,
- and J E Friedman
Effects of overexpression of human GLUT4 gene on maternal diabetes and fetal growth in spontaneous gestational diabetic C57BLKS/J Lepr(db/+) mice.
Diabetes May 1999 48:1061-1069; doi:10.2337/diabetes.48.5.1061
- Abstract
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- W Regittnig,
- Z Trajanoski,
- H J Leis,
- M Ellmerer,
- A Wutte,
- G Sendlhofer,
- L Schaupp,
- G A Brunner,
- P Wach,
- and T R Pieber
Plasma and interstitial glucose dynamics after intravenous glucose injection: evaluation of the single-compartment glucose distribution assumption in the minimal models.
Diabetes May 1999 48:1070-1081; doi:10.2337/diabetes.48.5.1070
- Abstract
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- D S Hardin,
- A LeBlanc,
- L Para,
- and D K Seilheimer
Hepatic insulin resistance and defects in substrate utilization in cystic fibrosis.
Diabetes May 1999 48:1082-1087; doi:10.2337/diabetes.48.5.1082
- Abstract
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- E S Tai,
- S C Emmanuel,
- S K Chew,
- B Y Tan,
- and C E Tan
Isolated low HDL cholesterol: an insulin-resistant state only in the presence of fasting hypertriglyceridemia.
Diabetes May 1999 48:1088-1092; doi:10.2337/diabetes.48.5.1088
- Abstract
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- F E Yakubu-Madus,
- W T Johnson,
- K M Zimmerman,
- J Dananberg,
- and M I Steinberg
Metabolic and hemodynamic effects of moxonidine in the Zucker diabetic fatty rat model of type 2 diabetes.
Diabetes May 1999 48:1093-1100; doi:10.2337/diabetes.48.5.1093
- Abstract
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- A Virkamäki and
- H Yki-Järvinen
Allosteric regulation of glycogen synthase and hexokinase by glucosamine-6-phosphate during glucosamine-induced insulin resistance in skeletal muscle and heart.
Diabetes May 1999 48:1101-1107; doi:10.2337/diabetes.48.5.1101
- Abstract
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- J M Fernández-Real,
- A Molina,
- M Broch,
- W Ricart,
- C Gutiérrez,
- R Casamitjana,
- J Vendrell,
- J Soler,
- and J M Gómez-Sáez
Tumor necrosis factor system activity is associated with insulin resistance and dyslipidemia in myotonic dystrophy.
Diabetes May 1999 48:1108-1112; doi:10.2337/diabetes.48.5.1108
- Abstract
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- S Jacob,
- J Machann,
- K Rett,
- K Brechtel,
- A Volk,
- W Renn,
- E Maerker,
- S Matthaei,
- F Schick,
- C D Claussen,
- and H U Häring
Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects.
Diabetes May 1999 48:1113-1119; doi:10.2337/diabetes.48.5.1113
- Abstract
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- Z Y Jiang,
- Q L Zhou,
- A Chatterjee,
- E P Feener,
- M G Myers, Jr,
- M F White,
- and G L King
Endothelin-1 modulates insulin signaling through phosphatidylinositol 3-kinase pathway in vascular smooth muscle cells.
Diabetes May 1999 48:1120-1130; doi:10.2337/diabetes.48.5.1120
- Abstract
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- T Marumo,
- V B Schini-Kerth,
- and R Busse
Vascular endothelial growth factor activates nuclear factor-kappaB and induces monocyte chemoattractant protein-1 in bovine retinal endothelial cells.
Diabetes May 1999 48:1131-1137; doi:10.2337/diabetes.48.5.1131
- Abstract
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- H Sakamaki,
- S Akazawa,
- M Ishibashi,
- K Izumino,
- H Takino,
- H Yamasaki,
- Y Yamaguchi,
- S Goto,
- Y Urata,
- T Kondo,
- and S Nagataki
Significance of glutathione-dependent antioxidant system in diabetes-induced embryonic malformations.
Diabetes May 1999 48:1138-1144; doi:10.2337/diabetes.48.5.1138
- Abstract
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- Y Hata,
- S L Rook,
- and L P Aiello
Basic fibroblast growth factor induces expression of VEGF receptor KDR through a protein kinase C and p44/p42 mitogen-activated protein kinase-dependent pathway.
Diabetes May 1999 48:1145-1155; doi:10.2337/diabetes.48.5.1145
- Abstract
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- A K Rao,
- V Chouhan,
- X Chen,
- L Sun,
- and G Boden
Activation of the tissue factor pathway of blood coagulation during prolonged hyperglycemia in young healthy men.
Diabetes May 1999 48:1156-1161; doi:10.2337/diabetes.48.5.1156
- Abstract
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- L Suaud,
- Y Hemimou,
- P Formstecher,
- and B Laine
Functional study of the E276Q mutant hepatocyte nuclear factor-4alpha found in type 1 maturity-onset diabetes of the young: impaired synergy with chicken ovalbumin upstream promoter transcription factor II on the hepatocyte nuclear factor-1 promoter.
Diabetes May 1999 48:1162-1167; doi:10.2337/diabetes.48.5.1162
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- H Ueda,
- H Ikegami,
- Y Kawaguchi,
- T Fujisawa,
- E Yamato,
- M Shibata,
- and T Ogihara
Genetic analysis of late-onset type 2 diabetes in a mouse model of human complex trait.
Diabetes May 1999 48:1168-1174; doi:10.2337/diabetes.48.5.1168
- Abstract
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- S C Elbein,
- M D Hoffman,
- K Teng,
- M F Leppert,
- and S J Hasstedt
A genome-wide search for type 2 diabetes susceptibility genes in Utah Caucasians.
Diabetes May 1999 48:1175-1182; doi:10.2337/diabetes.48.5.1175
- Abstract
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- I Hirayama,
- Z Yi,
- S Izumi,
- I Arai,
- W Suzuki,
- Y Nagamachi,
- H Kuwano,
- T Takeuchi,
- and T Izumi
Genetic analysis of obese diabetes in the TSOD mouse.
Diabetes May 1999 48:1183-1191; doi:10.2337/diabetes.48.5.1183
- Abstract
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- J W Kennedy,
- M F Hirshman,
- E V Gervino,
- J V Ocel,
- R A Forse,
- S J Hoenig,
- D Aronson,
- L J Goodyear,
- and E S Horton
Acute exercise induces GLUT4 translocation in skeletal muscle of normal human subjects and subjects with type 2 diabetes.
Diabetes May 1999 48:1192-1197; doi:10.2337/diabetes.48.5.1192
- Abstract
- Full Text (PDF)
- A D Cherrington
Banting Lecture 1997. Control of glucose uptake and release by the liver in vivo.
Diabetes May 1999 48:1198-1214; doi:10.2337/diabetes.48.5.1198
- Full Text (PDF)

Diabetes

Hyperglycemia and cardiovascular disease in type 2 diabetes.

Role of the human kidney in glucose counterregulation.

Insulin action on muscle protein kinetics and amino acid transport during recovery after resistance exercise.

Splanchnic and leg substrate exchange after ingestion of a natural mixed meal in humans.

NOD mice have a generalized defect in their response to transplantation tolerance induction.

Islet cell membrane antigens activate diabetogenic CD4+ T-cells in the BB/Wor rat.

Cellular immune responses to human islet proteins in antibody-positive type 2 diabetic patients.

Increased beta-cell proliferation and reduced mass before diabetes onset in the nonobese diabetic mouse.

Beta-cell hypertrophy in fa/fa rats is associated with basal glucose hypersensitivity and reduced SNARE protein expression.

cAMP enhances insulin secretion by an action on the ATP-sensitive K+ channel-independent pathway of glucose signaling in rat pancreatic islets.

Sustained proliferation of PDX-1+ cells derived from human islets.

Adenovirus-mediated overexpression of uncoupling protein-2 in pancreatic islets of Zucker diabetic rats increases oxidative activity and improves beta-cell function.

Glucose-lowering and insulin-sensitizing actions of exendin-4: studies in obese diabetic (ob/ob, db/db) mice, diabetic fatty Zucker rats, and diabetic rhesus monkeys (Macaca mulatta).

Overexpression of G11alpha and isoforms of phospholipase C in islet beta-cells reveals a lack of correlation between inositol phosphate accumulation and insulin secretion.

Glucagon-like peptide 1 increases insulin sensitivity in depancreatized dogs.

Endogenous glucose production and glucose effectiveness in type 2 diabetic subjects derived from stable-labeled minimal model approach.

Effects of overexpression of human GLUT4 gene on maternal diabetes and fetal growth in spontaneous gestational diabetic C57BLKS/J Lepr(db/+) mice.

Plasma and interstitial glucose dynamics after intravenous glucose injection: evaluation of the single-compartment glucose distribution assumption in the minimal models.

Hepatic insulin resistance and defects in substrate utilization in cystic fibrosis.

Isolated low HDL cholesterol: an insulin-resistant state only in the presence of fasting hypertriglyceridemia.

Metabolic and hemodynamic effects of moxonidine in the Zucker diabetic fatty rat model of type 2 diabetes.

Allosteric regulation of glycogen synthase and hexokinase by glucosamine-6-phosphate during glucosamine-induced insulin resistance in skeletal muscle and heart.

Tumor necrosis factor system activity is associated with insulin resistance and dyslipidemia in myotonic dystrophy.

Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects.

Endothelin-1 modulates insulin signaling through phosphatidylinositol 3-kinase pathway in vascular smooth muscle cells.

Vascular endothelial growth factor activates nuclear factor-kappaB and induces monocyte chemoattractant protein-1 in bovine retinal endothelial cells.

Significance of glutathione-dependent antioxidant system in diabetes-induced embryonic malformations.

Basic fibroblast growth factor induces expression of VEGF receptor KDR through a protein kinase C and p44/p42 mitogen-activated protein kinase-dependent pathway.

Activation of the tissue factor pathway of blood coagulation during prolonged hyperglycemia in young healthy men.

Functional study of the E276Q mutant hepatocyte nuclear factor-4alpha found in type 1 maturity-onset diabetes of the young: impaired synergy with chicken ovalbumin upstream promoter transcription factor II on the hepatocyte nuclear factor-1 promoter.

Genetic analysis of late-onset type 2 diabetes in a mouse model of human complex trait.

A genome-wide search for type 2 diabetes susceptibility genes in Utah Caucasians.

Genetic analysis of obese diabetes in the TSOD mouse.

Acute exercise induces GLUT4 translocation in skeletal muscle of normal human subjects and subjects with type 2 diabetes.

Banting Lecture 1997. Control of glucose uptake and release by the liver in vivo.

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