Table of Contents

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- S Seino,
- T Iwanaga,
- K Nagashima,
- and T Miki
Diverse roles of K(ATP) channels learned from Kir6.2 genetically engineered mice.
Diabetes March 2000 49:311-318; doi:10.2337/diabetes.49.3.311
- Abstract
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- E Nisoli,
- M O Carruba,
- C Tonello,
- C Macor,
- G Federspil,
- and R Vettor
Induction of fatty acid translocase/CD36, peroxisome proliferator-activated receptor-gamma2, leptin, uncoupling proteins 2 and 3, and tumor necrosis factor-alpha gene expression in human subcutaneous fat by lipid infusion.
Diabetes March 2000 49:319-324; doi:10.2337/diabetes.49.3.319
- Abstract
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- J F Wojtaszewski,
- B F Hansen,
- Gade,
- B Kiens,
- J F Markuns,
- L J Goodyear,
- and E A Richter
Insulin signaling and insulin sensitivity after exercise in human skeletal muscle.
Diabetes March 2000 49:325-331; doi:10.2337/diabetes.49.3.325
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- Y Yamamoto,
- Y Yoshimasa,
- M Koh,
- J Suga,
- H Masuzaki,
- Y Ogawa,
- K Hosoda,
- H Nishimura,
- Y Watanabe,
- G Inoue,
- and K Nakao
Constitutively active mitogen-activated protein kinase kinase increases GLUT1 expression and recruits both GLUT1 and GLUT4 at the cell surface in 3T3-L1 adipocytes.
Diabetes March 2000 49:332-339; doi:10.2337/diabetes.49.3.332
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- Z Ling,
- M Van de Casteele,
- D L Eizirik,
- and D G Pipeleers
Interleukin-1beta-induced alteration in a beta-cell phenotype can reduce cellular sensitivity to conditions that cause necrosis but not to cytokine-induced apoptosis.
Diabetes March 2000 49:340-345; doi:10.2337/diabetes.49.3.340
- Abstract
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- L B Maggi, Jr,
- H Sadeghi,
- C Weigand,
- A L Scarim,
- M R Heitmeier,
- and J A Corbett
Anti-inflammatory actions of 15-deoxy-delta 12,14-prostaglandin J2 and troglitazone: evidence for heat shock-dependent and -independent inhibition of cytokine-induced inducible nitric oxide synthase expression.
Diabetes March 2000 49:346-355; doi:10.2337/diabetes.49.3.346
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- C J Hawkes,
- N C Schloot,
- J Marks,
- S J Willemen,
- J W Drijfhout,
- E K Mayer,
- M R Christie,
- and B O Roep
T-cell lines reactive to an immunodominant epitope of the tyrosine phosphatase-like autoantigen IA-2 in type 1 diabetes.
Diabetes March 2000 49:356-366; doi:10.2337/diabetes.49.3.356
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- B J Kim,
- Y H Kim,
- S Kim,
- J W Kim,
- J Y Koh,
- S H Oh,
- M K Lee,
- K W Kim,
- and M S Lee
Zinc as a paracrine effector in pancreatic islet cell death.
Diabetes March 2000 49:367-372; doi:10.2337/diabetes.49.3.367
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- R M Watanabe and
- R N Bergman
Accurate measurement of endogenous insulin secretion does not require separate assessment of C-peptide kinetics.
Diabetes March 2000 49:373-382; doi:10.2337/diabetes.49.3.373
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- H Brown,
- B Meister,
- J Deeney,
- B E Corkey,
- S N Yang,
- O Larsson,
- C J Rhodes,
- S Seino,
- P O Berggren,
- and G Fried
Synaptotagmin III isoform is compartmentalized in pancreatic beta-cells and has a functional role in exocytosis.
Diabetes March 2000 49:383-391; doi:10.2337/diabetes.49.3.383
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- T P Iismaa,
- E A Kerr,
- J R Wilson,
- L Carpenter,
- N Sims,
- and T J Biden
Quantitative and functional characterization of muscarinic receptor subtypes in insulin-secreting cell lines and rat pancreatic islets.
Diabetes March 2000 49:392-398; doi:10.2337/diabetes.49.3.392
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- A Carpentier,
- S D Mittelman,
- R N Bergman,
- A Giacca,
- and G F Lewis
Prolonged elevation of plasma free fatty acids impairs pancreatic beta-cell function in obese nondiabetic humans but not in individuals with type 2 diabetes.
Diabetes March 2000 49:399-408; doi:10.2337/diabetes.49.3.399
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- P E Squires,
- T E Harris,
- S J Persaud,
- S B Curtis,
- A M Buchan,
- and P M Jones
The extracellular calcium-sensing receptor on human beta-cells negatively modulates insulin secretion.
Diabetes March 2000 49:409-417; doi:10.2337/diabetes.49.3.409
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- W M Macfarlane,
- R M Shepherd,
- K E Cosgrove,
- R F James,
- M J Dunne,
- and K Docherty
Glucose modulation of insulin mRNA levels is dependent on transcription factor PDX-1 and occurs independently of changes in intracellular Ca2+.
Diabetes March 2000 49:418-423; doi:10.2337/diabetes.49.3.418
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- H E Hohmeier,
- H Mulder,
- G Chen,
- R Henkel-Rieger,
- M Prentki,
- and C B Newgard
Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion.
Diabetes March 2000 49:424-430; doi:10.2337/diabetes.49.3.424
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- P J Scarpace,
- M Matheny,
- R L Moore,
- and N Tümer
Impaired leptin responsiveness in aged rats.
Diabetes March 2000 49:431-435; doi:10.2337/diabetes.49.3.431
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- T Nakagawa,
- A Tsuchida,
- Y Itakura,
- T Nonomura,
- M Ono,
- F Hirota,
- T Inoue,
- C Nakayama,
- M Taiji,
- and H Noguchi
Brain-derived neurotrophic factor regulates glucose metabolism by modulating energy balance in diabetic mice.
Diabetes March 2000 49:436-444; doi:10.2337/diabetes.49.3.436
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- R S Lindsay,
- D Dabelea,
- J Roumain,
- R L Hanson,
- P H Bennett,
- and W C Knowler
Type 2 diabetes and low birth weight: the role of paternal inheritance in the association of low birth weight and diabetes.
Diabetes March 2000 49:445-449; doi:10.2337/diabetes.49.3.445
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- S E Joseph,
- N Heaton,
- D Potter,
- A Pernet,
- M A Umpleby,
- and S A Amiel
Renal glucose production compensates for the liver during the anhepatic phase of liver transplantation.
Diabetes March 2000 49:450-456; doi:10.2337/diabetes.49.3.450
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- P A Crossey,
- J S Jones,
- and J P Miell
Dysregulation of the insulin/IGF binding protein-1 axis in transgenic mice is associated with hyperinsulinemia and glucose intolerance.
Diabetes March 2000 49:457-465; doi:10.2337/diabetes.49.3.457
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- C Sassy-Prigent,
- D Heudes,
- C Mandet,
- M F Bélair,
- O Michel,
- B Perdereau,
- J Bariéty,
- and P Bruneval
Early glomerular macrophage recruitment in streptozotocin-induced diabetic rats.
Diabetes March 2000 49:466-475; doi:10.2337/diabetes.49.3.466
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- R Nosadini,
- M Velussi,
- E Brocco,
- M Bruseghin,
- C Abaterusso,
- A Saller,
- M Dalla Vestra,
- A Carraro,
- E Bortoloso,
- M Sambataro,
- I Barzon,
- F Frigato,
- B Muollo,
- M Chiesura-Corona,
- G Pacini,
- B Baggio,
- F Piarulli,
- A Sfriso,
- and P Fioretto
Course of renal function in type 2 diabetic patients with abnormalities of albumin excretion rate.
Diabetes March 2000 49:476-484; doi:10.2337/diabetes.49.3.476
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- A Jager,
- V W van Hinsbergh,
- P J Kostense,
- J J Emeis,
- G Nijpels,
- J M Dekker,
- R J Heine,
- L M Bouter,
- and C D Stehouwer
Increased levels of soluble vascular cell adhesion molecule 1 are associated with risk of cardiovascular mortality in type 2 diabetes: the Hoorn study.
Diabetes March 2000 49:485-491; doi:10.2337/diabetes.49.3.485
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- M P Marron,
- A Zeidler,
- L J Raffel,
- S E Eckenrode,
- J J Yang,
- D I Hopkins,
- H J Garchon,
- C O Jacob,
- M Serrano-Rios,
- M T Martinez Larrad,
- Y Park,
- J F Bach,
- J I Rotter,
- M C Yang,
- and J X She
Genetic and physical mapping of a type 1 diabetes susceptibility gene (IDDM12) to a 100-kb phagemid artificial chromosome clone containing D2S72-CTLA4-D2S105 on chromosome 2q33.
Diabetes March 2000 49:492-499; doi:10.2337/diabetes.49.3.492
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- S Neugebauer,
- T Baba,
- and T Watanabe
Association of the nitric oxide synthase gene polymorphism with an increased risk for progression to diabetic nephropathy in type 2 diabetes.
Diabetes March 2000 49:500-503; doi:10.2337/diabetes.49.3.500
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- M A Pani,
- M Knapp,
- H Donner,
- J Braun,
- M P Baur,
- K H Usadel,
- and K Badenhoop
Vitamin D receptor allele combinations influence genetic susceptibility to type 1 diabetes in Germans.
Diabetes March 2000 49:504-507; doi:10.2337/diabetes.49.3.504
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- D Owerbach
Physical and genetic mapping of IDDM8 on chromosome 6q27.
Diabetes March 2000 49:508-512; doi:10.2337/diabetes.49.3.508
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- B D Mitchell,
- S A Cole,
- W C Hsueh,
- A G Comuzzie,
- J Blangero,
- J W MacCluer,
- and J E Hixson
Linkage of serum insulin concentrations to chromosome 3p in Mexican Americans.
Diabetes March 2000 49:513-516; doi:10.2337/diabetes.49.3.513
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- J M Fernández-Real,
- M Broch,
- J Vendrell,
- C Gutiérrez,
- R Casamitjana,
- M Pugeat,
- C Richart,
- and W Ricart
Interleukin-6 gene polymorphism and insulin sensitivity.
Diabetes March 2000 49:517-520; doi:10.2337/diabetes.49.3.517
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- S De Cosmo,
- A Argiolas,
- G Miscio,
- S Thomas,
- G P Piras,
- R Trevisan,
- P C Perin,
- S Bacci,
- L Zucaro,
- M Margaglione,
- L Frittitta,
- A Pizzuti,
- V Tassi,
- G C Viberti,
- and V Trischitta
A PC-1 amino acid variant (K121Q) is associated with faster progression of renal disease in patients with type 1 diabetes and albuminuria.
Diabetes March 2000 49:521-524; doi:10.2337/diabetes.49.3.521
- Abstract
- Full Text (PDF)

Diverse roles of K(ATP) channels learned from Kir6.2 genetically engineered mice.

Induction of fatty acid translocase/CD36, peroxisome proliferator-activated receptor-gamma2, leptin, uncoupling proteins 2 and 3, and tumor necrosis factor-alpha gene expression in human subcutaneous fat by lipid infusion.

Insulin signaling and insulin sensitivity after exercise in human skeletal muscle.

Constitutively active mitogen-activated protein kinase kinase increases GLUT1 expression and recruits both GLUT1 and GLUT4 at the cell surface in 3T3-L1 adipocytes.

Interleukin-1beta-induced alteration in a beta-cell phenotype can reduce cellular sensitivity to conditions that cause necrosis but not to cytokine-induced apoptosis.

Anti-inflammatory actions of 15-deoxy-delta 12,14-prostaglandin J2 and troglitazone: evidence for heat shock-dependent and -independent inhibition of cytokine-induced inducible nitric oxide synthase expression.

T-cell lines reactive to an immunodominant epitope of the tyrosine phosphatase-like autoantigen IA-2 in type 1 diabetes.

Zinc as a paracrine effector in pancreatic islet cell death.

Accurate measurement of endogenous insulin secretion does not require separate assessment of C-peptide kinetics.

Synaptotagmin III isoform is compartmentalized in pancreatic beta-cells and has a functional role in exocytosis.

Quantitative and functional characterization of muscarinic receptor subtypes in insulin-secreting cell lines and rat pancreatic islets.

Prolonged elevation of plasma free fatty acids impairs pancreatic beta-cell function in obese nondiabetic humans but not in individuals with type 2 diabetes.

The extracellular calcium-sensing receptor on human beta-cells negatively modulates insulin secretion.

Glucose modulation of insulin mRNA levels is dependent on transcription factor PDX-1 and occurs independently of changes in intracellular Ca2+.

Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion.

Impaired leptin responsiveness in aged rats.

Brain-derived neurotrophic factor regulates glucose metabolism by modulating energy balance in diabetic mice.

Type 2 diabetes and low birth weight: the role of paternal inheritance in the association of low birth weight and diabetes.

Renal glucose production compensates for the liver during the anhepatic phase of liver transplantation.

Dysregulation of the insulin/IGF binding protein-1 axis in transgenic mice is associated with hyperinsulinemia and glucose intolerance.

Early glomerular macrophage recruitment in streptozotocin-induced diabetic rats.

Course of renal function in type 2 diabetic patients with abnormalities of albumin excretion rate.

Increased levels of soluble vascular cell adhesion molecule 1 are associated with risk of cardiovascular mortality in type 2 diabetes: the Hoorn study.

Genetic and physical mapping of a type 1 diabetes susceptibility gene (IDDM12) to a 100-kb phagemid artificial chromosome clone containing D2S72-CTLA4-D2S105 on chromosome 2q33.

Association of the nitric oxide synthase gene polymorphism with an increased risk for progression to diabetic nephropathy in type 2 diabetes.

Vitamin D receptor allele combinations influence genetic susceptibility to type 1 diabetes in Germans.

Physical and genetic mapping of IDDM8 on chromosome 6q27.

Linkage of serum insulin concentrations to chromosome 3p in Mexican Americans.

Interleukin-6 gene polymorphism and insulin sensitivity.

A PC-1 amino acid variant (K121Q) is associated with faster progression of renal disease in patients with type 1 diabetes and albuminuria.

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