The inhibition of the incretin effect of forskolin by orlistat. Cells
were preincubated for 30 min with the indicated concentrations of orlistat in
the absence of glucose. The media were then changed to ones containing 5
mmol/l glucose with or without 10 μmol/l forskolin, plus the indicated
orlistat, and the insulin released was measured after 30 min of incubation.
Data shown are means ± SE of 4 wells in a 24-well plate. [cjs2098], Control; [cjs2113], forskolin.