Circulating Ghrelin Levels Are Decreased in Human Obesity

TABLE 1

Demographic and biochemical characteristics of the study population

Lean Caucasians Obese Caucasians Lean Pima Indians Obese Pima Indians
n 7 8 7 8
Sex
 Female 3 4 3 4
 Male 4 4 4 4
Age (years) 32 ± 11 30 ± 7 33 ± 4 32 ± 5
Body weight (kg) 71.4 ± 9.8 109.8 ± 16.8 70.3 ± 9.6 109 ± 15.2
BMI (kg/m2) 25.4 ± 2.3 38.2 ± 4.8 24.0 ± 1.9 37.9 ± 6.6
Body fat (%) 22 ± 9 35 ± 7 24 ± 7 35 ± 5
Plasma ghrelin (fmol/ml) 155 ± 25 106 ± 23 95 ± 13 80 ± 36
Plasma glucose (mg/dl) 87 ± 7 91 ± 4 89 ± 6 95 ± 7
Plasma insulin (μU/ml) 4 ± 3 10 ± 3 6 ± 3 18 ± 10
Plasma leptin (ng/ml) 8 ± 7 53 ± 47 10 ± 9 35 ± 27
  • Data are means ± SD unless otherwise indicated. Caucasians and Pima Indians in the lean and obese groups were matched for age, sex, and body weight.

This Article

  1. Diabetes vol. 50 no. 4 707-709