Table of Contents

Rapid Publication

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- Judith M. Thomas,
- Juan L. Contreras,
- Cheryl A. Smyth,
- Andrew Lobashevsky,
- Stacie Jenkins,
- William J. Hubbard,
- Devin E. Eckhoff,
- Scott Stavrou,
- David M. Neville Jr.,
- and Francis T. Thomas
Successful Reversal of Streptozotocin-Induced Diabetes With Stable Allogeneic Islet Function in a Preclinical Model of Type 1 Diabetes
Diabetes June 2001 50:1227-1236; doi:10.2337/diabetes.50.6.1227

Metabolism and Signal Transduction

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- Susanne E. la Fleur,
- Andries Kalsbeek,
- Joke Wortel,
- Madelon L. Fekkes,
- and Ruud M. Buijs
A Daily Rhythm in Glucose Tolerance: A Role for the Suprachiasmatic Nucleus
Diabetes June 2001 50:1237-1243; doi:10.2337/diabetes.50.6.1237
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- Gerolama Condorelli,
- Giovanni Vigliotta,
- Alessandra Trencia,
- Maria Alessandra Maitan,
- Matilde Caruso,
- Claudia Miele,
- Francesco Oriente,
- Stefania Santopietro,
- Pietro Formisano,
- and Francesco Beguinot
Protein Kinase C (PKC)-α Activation Inhibits PKC-ζ and Mediates the Action of PED/PEA-15 on Glucose Transport in the L6 Skeletal Muscle Cells
Diabetes June 2001 50:1244-1252; doi:10.2337/diabetes.50.6.1244
Select this article
- Vladimir B. Ritov and
- David E. Kelley
Hexokinase Isozyme Distribution in Human Skeletal Muscle
Diabetes June 2001 50:1253-1262; doi:10.2337/diabetes.50.6.1253
Select this article
- Kitt Falk Petersen,
- Didier Laurent,
- Chunli Yu,
- Gary W. Cline,
- and Gerald I. Shulman
Stimulating Effects of Low-Dose Fructose on Insulin-Stimulated Hepatic Glycogen Synthesis in Humans
Diabetes June 2001 50:1263-1268; doi:10.2337/diabetes.50.6.1263

Immunology and Transplantation

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- Akihisa Imagawa,
- Toshiaki Hanafusa,
- Shinji Tamura,
- Makoto Moriwaki,
- Naoto Itoh,
- Koji Yamamoto,
- Hiromi Iwahashi,
- Kazuya Yamagata,
- Masako Waguri,
- Takao Nanmo,
- Sae Uno,
- Hiromu Nakajima,
- Mitsuyoshi Namba,
- Sumio Kawata,
- Jun-ichiro Miyagawa,
- and Yuji Matsuzawa
Pancreatic Biopsy as a Procedure for Detecting In Situ Autoimmune Phenomena in Type 1 Diabetes: Close Correlation Between Serological Markers and Histological Evidence of Cellular Autoimmunity
Diabetes June 2001 50:1269-1273; doi:10.2337/diabetes.50.6.1269
Select this article
- Norio Abiru,
- Aristides K. Maniatis,
- Liping Yu,
- Dongmei Miao,
- Hiroaki Moriyama,
- Dale Wegmann,
- and George S. Eisenbarth
Peptide and Major Histocompatibility Complex–Specific Breaking of Humoral Tolerance to Native Insulin With the B9-23 Peptide in Diabetes-Prone and Normal Mice
Diabetes June 2001 50:1274-1281; doi:10.2337/diabetes.50.6.1274

Islet Studies

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- Rémy Burcelin and
- Bernard Thorens
Evidence That Extrapancreatic GLUT2-Dependent Glucose Sensors Control Glucagon Secretion
Diabetes June 2001 50:1282-1289; doi:10.2337/diabetes.50.6.1282
Select this article
- Massimo Federici,
- Marta Hribal,
- Lucia Perego,
- Marco Ranalli,
- Zaira Caradonna,
- Carla Perego,
- Luciana Usellini,
- Rita Nano,
- Paolo Bonini,
- Federico Bertuzzi,
- Lionel N.J.L. Marlier,
- Alberto M. Davalli,
- Orazio Carandente,
- Antonio E. Pontiroli,
- Gerry Melino,
- Piero Marchetti,
- Renato Lauro,
- Giorgio Sesti,
- and Franco Folli
High Glucose Causes Apoptosis in Cultured Human Pancreatic Islets of Langerhans: A Potential Role for Regulation of Specific Bcl Family Genes Toward an Apoptotic Cell Death Program
Diabetes June 2001 50:1290-1301; doi:10.2337/diabetes.50.6.1290
Select this article
- Catherine B. Chan,
- Domenica De Leo,
- Jamie W. Joseph,
- Timothy S. McQuaid,
- Xiao Fang Ha,
- Fang Xu,
- Robert G. Tsushima,
- Peter S. Pennefather,
- Anne Marie F. Salapatek,
- and Michael B. Wheeler
Increased Uncoupling Protein-2 Levels in β-cells Are Associated With Impaired Glucose-Stimulated Insulin Secretion: Mechanism of Action
Diabetes June 2001 50:1302-1310; doi:10.2337/diabetes.50.6.1302
Select this article
- Anne-Dominique Lajoix,
- Hubbert Reggio,
- Thierry Chardès,
- Sylvie Péraldi-Roux,
- Florence Tribillac,
- Michèle Roye,
- Samuel Dietz,
- Christophe Broca,
- Michèle Manteghetti,
- Gérard Ribes,
- Claes B. Wollheim,
- and René Gross
A Neuronal Isoform of Nitric Oxide Synthase Expressed in Pancreatic β-Cells Controls Insulin Secretion
Diabetes June 2001 50:1311-1323; doi:10.2337/diabetes.50.6.1311

Complications

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- Hironori Nakagami,
- Ryuichi Morishita,
- Kei Yamamoto,
- Shin-ichi Yoshimura,
- Yoshiaki Taniyama,
- Motokuni Aoki,
- Hiroaki Matsubara,
- Shokei Kim,
- Yasufumi Kaneda,
- and Toshio Ogihara
Phosphorylation of p38 Mitogen-Activated Protein Kinase Downstream of Bax-Caspase-3 Pathway Leads to Cell Death Induced by High d-Glucose in Human Endothelial Cells
Diabetes June 2001 50:1472-1481; doi:10.2337/diabetes.50.6.1472
Select this article
- Chhinder P. Sodhi,
- Sarojini A. Phadke,
- Daniel Batlle,
- and Atul Sahai
Hypoxia Stimulates Osteopontin Expression and Proliferation of Cultured Vascular Smooth Muscle Cells: Potentiation by High Glucose
Diabetes June 2001 50:1482-1490; doi:10.2337/diabetes.50.6.1482
Select this article
- Sho-ichi Yamagishi,
- Diane Edelstein,
- Xue-liang Du,
- and Michael Brownlee
Hyperglycemia Potentiates Collagen-Induced Platelet Activation Through Mitochondrial Superoxide Overproduction
Diabetes June 2001 50:1491-1494; doi:10.2337/diabetes.50.6.1491
Select this article
- Chen-Hsiung Yeh,
- Lydia Sturgis,
- Joe Haidacher,
- Xue-Nong Zhang,
- Sidney J. Sherwood,
- Robert J. Bjercke,
- Ondrej Juhasz,
- Michael T. Crow,
- Ronald G. Tilton,
- and Larry Denner
Requirement for p38 and p44/p42 Mitogen-Activated Protein Kinases in RAGE-Mediated Nuclear Factor-κB Transcriptional Activation and Cytokine Secretion
Diabetes June 2001 50:1495-1504; doi:10.2337/diabetes.50.6.1495
Select this article
- Barry I. Hudson,
- Max H. Stickland,
- T. Simon Futers,
- and Peter J. Grant
Effects of Novel Polymorphisms in the RAGE Gene on Transcriptional Regulation and Their Association With Diabetic Retinopathy
Diabetes June 2001 50:1505-1511; doi:10.2337/diabetes.50.6.1505

Erratum

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Errata
Diabetes June 2001 50:1512; doi:10.2337/diabetes.50.6.1512
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Errata
Diabetes June 2001 50:1512; doi:10.2337/diabetes.50.6.1512-a
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Errata
Diabetes June 2001 50:1512; doi:10.2337/diabetes.50.6.1512-b

Diabetes

Rapid Publication

Successful Reversal of Streptozotocin-Induced Diabetes With Stable Allogeneic Islet Function in a Preclinical Model of Type 1 Diabetes

Metabolism and Signal Transduction

A Daily Rhythm in Glucose Tolerance: A Role for the Suprachiasmatic Nucleus

Protein Kinase C (PKC)-α Activation Inhibits PKC-ζ and Mediates the Action of PED/PEA-15 on Glucose Transport in the L6 Skeletal Muscle Cells

Hexokinase Isozyme Distribution in Human Skeletal Muscle

Stimulating Effects of Low-Dose Fructose on Insulin-Stimulated Hepatic Glycogen Synthesis in Humans

Immunology and Transplantation

Pancreatic Biopsy as a Procedure for Detecting In Situ Autoimmune Phenomena in Type 1 Diabetes: Close Correlation Between Serological Markers and Histological Evidence of Cellular Autoimmunity

Peptide and Major Histocompatibility Complex–Specific Breaking of Humoral Tolerance to Native Insulin With the B9-23 Peptide in Diabetes-Prone and Normal Mice

Islet Studies

Evidence That Extrapancreatic GLUT2-Dependent Glucose Sensors Control Glucagon Secretion

High Glucose Causes Apoptosis in Cultured Human Pancreatic Islets of Langerhans: A Potential Role for Regulation of Specific Bcl Family Genes Toward an Apoptotic Cell Death Program

Increased Uncoupling Protein-2 Levels in β-cells Are Associated With Impaired Glucose-Stimulated Insulin Secretion: Mechanism of Action

A Neuronal Isoform of Nitric Oxide Synthase Expressed in Pancreatic β-Cells Controls Insulin Secretion

Pathophysiology

GLUT4 Is Reduced in Slow Muscle Fibers of Type 2 Diabetic Patients: Is Insulin Resistance in Type 2 Diabetes a Slow, Type 1 Fiber Disease?

Ezetimibe, a Potent Cholesterol Absorption Inhibitor, Normalizes Combined Dyslipidemia in Obese Hyperinsulinemic Hamsters

Protein Metabolism in Clinically Stable Adult Cystic Fibrosis Patients With Abnormal Glucose Tolerance

Decreased Susceptibility to Fatty Acid–Induced Peripheral Tissue Insulin Resistance in Women

Type 2 Diabetes Impairs Splanchnic Uptake of Glucose but Does Not Alter Intestinal Glucose Absorption During Enteral Glucose Feeding: Additional Evidence for a Defect in Hepatic Glucokinase Activity

Assessment of Hepatic Insulin Action in Obese Type 2 Diabetic Patients

Resistance to Exercise-Induced Increase in Glucose Uptake During Hyperinsulinemia in Insulin-Resistant Skeletal Muscle of Patients With Type 1 Diabetes

The HIV Protease Inhibitor Indinavir Impairs Sterol Regulatory Element-Binding Protein-1 Intranuclear Localization, Inhibits Preadipocyte Differentiation, and Induces Insulin Resistance

Increased Fatty Acid Uptake and Altered Fatty Acid Metabolism in Insulin-Resistant Muscle of Obese Zucker Rats

The HIV Protease Inhibitor Indinavir Decreases Insulin- and Contraction-Stimulated Glucose Transport in Skeletal Muscle

The Effect of Systemic Versus Portal Insulin Delivery in Pancreas Transplantation on Insulin Action and VLDL Metabolism

IGF-1 Overexpression Inhibits the Development of Diabetic Cardiomyopathy and Angiotensin II–Mediated Oxidative Stress

The HIV Protease Inhibitor Nelfinavir Induces Insulin Resistance and Increases Basal Lipolysis in 3T3-L1 Adipocytes

Increased Prevalence of Microthromboses in Retinal Capillaries of Diabetic Individuals

Transgenic Overexpression of Leptin Rescues Insulin Resistance and Diabetes in a Mouse Model of Lipoatrophic Diabetes

Insulin Sensitivity of Suppression of Endogenous Glucose Production Is the Single Most Important Determinant of Glucose Tolerance

Subcellular Localization of Insulin Receptor Substrate Family Proteins Associated With Phosphatidylinositol 3-Kinase Activity and Alterations in Lipolysis in Primary Mouse Adipocytes From IRS-1 Null Mice

The Antihyperglycemic Drug α-Lipoic Acid Stimulates Glucose Uptake via Both GLUT4 Translocation and GLUT4 Activation: Potential Role of p38 Mitogen-Activated Protein Kinase in GLUT4 Activation

Complications

Phosphorylation of p38 Mitogen-Activated Protein Kinase Downstream of Bax-Caspase-3 Pathway Leads to Cell Death Induced by High d-Glucose in Human Endothelial Cells

Hypoxia Stimulates Osteopontin Expression and Proliferation of Cultured Vascular Smooth Muscle Cells: Potentiation by High Glucose

Hyperglycemia Potentiates Collagen-Induced Platelet Activation Through Mitochondrial Superoxide Overproduction

Requirement for p38 and p44/p42 Mitogen-Activated Protein Kinases in RAGE-Mediated Nuclear Factor-κB Transcriptional Activation and Cytokine Secretion

Effects of Novel Polymorphisms in the RAGE Gene on Transcriptional Regulation and Their Association With Diabetic Retinopathy

Erratum

Errata

Errata

Errata

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