Diabetes: 51 (1)

January 01 2002; volume 51 issue 1

Rapid Publication

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A P387L Variant in Protein Tyrosine Phosphatase-1B (PTP-1B) Is Associated With Type 2 Diabetes and Impaired Serine Phosphorylation of PTP-1B In Vitro
Søren M. Echwald, Helle Bach, Henrik Vestergaard, Bjørn Richelsen, Kurt Kristensen, Thomas Drivsholm, Knut Borch-Johnsen, Torben Hansen and Oluf Pedersen

Diabetes 2002 Jan; 51 (1): 1-6. https://doi.org/10.2337/diabetes.51.1.1

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Banting Lecture 2001

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Banting Lecture 2001Dysregulation of Fatty Acid Metabolism in the Etiology of Type 2 Diabetes
J. Denis McGarry

Diabetes 2002 Jan; 51 (1): 7-18. https://doi.org/10.2337/diabetes.51.1.7

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Metabolism and Signal Transduction

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Phosphatidylinositol 3-Kinase Redistribution Is Associated With Skeletal Muscle Insulin Resistance in Gestational Diabetes Mellitus
Jianhua Shao, Hiroshi Yamashita, Liping Qiao, Boris Draznin and Jacob E. Friedman

Diabetes 2002 Jan; 51 (1): 19-29. https://doi.org/10.2337/diabetes.51.1.19

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Regulation of Glucose Transport and Insulin Signaling by Troglitazone or Metformin in Adipose Tissue of Type 2 Diabetic Subjects
Theodore P. Ciaraldi, Alice P.S. Kong, Neelima V. Chu, Dennis D. Kim, Sunita Baxi, Mattias Loviscach, Ray Plodkowski, Richard Reitz, Michael Caulfield, Sunder Mudaliar and Robert R. Henry

Diabetes 2002 Jan; 51 (1): 30-36. https://doi.org/10.2337/diabetes.51.1.30

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Association of the T-G Polymorphism in Adiponectin (Exon 2) With Obesity and Insulin SensitivityInteraction With Family History of Type 2 Diabetes
Michael Stumvoll, Otto Tschritter, Andreas Fritsche, Harald Staiger, Walter Renn, Melanie Weisser, Fausto Machicao and Hans Häring

Diabetes 2002 Jan; 51 (1): 37-41. https://doi.org/10.2337/diabetes.51.1.37

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Skeletal Muscle Microvascular Recruitment by Physiological Hyperinsulinemia Precedes Increases in Total Blood Flow
M.A. Vincent, D. Dawson, A.D.H. Clark, J.R. Lindner, S. Rattigan, M.G. Clark and E.J. Barrett

Diabetes 2002 Jan; 51 (1): 42-48. https://doi.org/10.2337/diabetes.51.1.42

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Hepatic Glycogen Metabolism in Type 1 Diabetes After Long-Term Near Normoglycemia
Martin G. Bischof, Elisabeth Bernroider, Martin Krssak, Michael Krebs, Harald Stingl, Peter Nowotny, Chunlin Yu, Gerald I. Shulman, Werner Waldhäusl and Michael Roden

Diabetes 2002 Jan; 51 (1): 49-54. https://doi.org/10.2337/diabetes.51.1.49

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Immunology and Transplantation

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Human Pancreatic Islets Produce and Secrete MCP-1/CCL2: Relevance in Human Islet Transplantation
Lorenzo Piemonti, Biagio Eugenio Leone, Rita Nano, Alessandra Saccani, Paolo Monti, Paola Maffi, Giancarlo Bianchi, Antonio Sica, Giuseppe Peri, Raffaella Melzi, Luca Aldrighetti, Antonio Secchi, Valerio Di Carlo, Paola Allavena and Federico Bertuzzi

Diabetes 2002 Jan; 51 (1): 55-65. https://doi.org/10.2337/diabetes.51.1.55

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β-Cell Death and Mass in Syngeneically Transplanted Islets Exposed to Short- and Long-Term Hyperglycemia
Montserrat Biarnés, Marta Montolio, Victor Nacher, Mercè Raurell, Joan Soler and Eduard Montanya

Diabetes 2002 Jan; 51 (1): 66-72. https://doi.org/10.2337/diabetes.51.1.66

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Oral Exposure to Diabetes-Promoting Food or Immunomodulators in Neonates Alters Gut Cytokines and Diabetes
Fraser W. Scott, Paul Rowsell, Gen-Sheng Wang, Karolina Burghardt, Hubert Kolb and Stefanie Flohé

Diabetes 2002 Jan; 51 (1): 73-78. https://doi.org/10.2337/diabetes.51.1.73

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A Distinct Th1 Immune Response Precedes the Described Th2 Response in Islet Xenograft Rejection
Henrik Krook, Anette Hagberg, Zhenshun Song, Ulf Landegren, Lars Wennberg and Olle Korsgren

Diabetes 2002 Jan; 51 (1): 79-86. https://doi.org/10.2337/diabetes.51.1.79

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Islet Study

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Phosphatidylinositol 3-Kinase Suppresses Glucose-Stimulated Insulin Secretion by Affecting Post-Cytosolic [Ca²⁺] Elevation Signals
Kazuhiro Eto, Tokuyuki Yamashita, Yoshiharu Tsubamoto, Yasuo Terauchi, Kenzo Hirose, Naoto Kubota, Shigeo Yamashita, Junko Taka, Shinobu Satoh, Hisahiko Sekihara, Kazuyuki Tobe, Masamitsu Iino, Mitsuhiko Noda, Satoshi Kimura and Takashi Kadowaki

Diabetes 2002 Jan; 51 (1): 87-97. https://doi.org/10.2337/diabetes.51.1.87

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A Key Role for β-Cell Cytosolic Phospholipase A₂ in the Maintenance of Insulin Stores But Not in the Initiation of Insulin Secretion
Shanta J. Persaud, Helen M. Roderigo-Milne, Paul E. Squires, David Sugden, Caroline P.D. Wheeler-Jones, Phil J. Marsh, Véronique D. Belin, Melanie J. Luther and Peter M. Jones

Diabetes 2002 Jan; 51 (1): 98-104. https://doi.org/10.2337/diabetes.51.1.98

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Intracellular pH Plays a Critical Role in Glucose-Induced Time-Dependent Potentiation of Insulin Release in Rat Islets
Subhadra C. Gunawardana and Geoffrey W.G. Sharp

Diabetes 2002 Jan; 51 (1): 105-113. https://doi.org/10.2337/diabetes.51.1.105

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Overexpression of Dominant-Negative Mutant Hepatocyte Nuclear Factor-1α in Pancreatic β-Cells Causes Abnormal Islet Architecture With Decreased Expression of E-Cadherin, Reduced β-cell Proliferation, and Diabetes
Kazuya Yamagata, Takao Nammo, Makoto Moriwaki, Arisa Ihara, Katsumi Iizuka, Qin Yang, Tomomi Satoh, Ming Li, Rikako Uenaka, Kohei Okita, Hiromi Iwahashi, Qian Zhu, Yang Cao, Akihisa Imagawa, Yoshihiro Tochino, Toshiaki Hanafusa, Jun-ichiro Miyagawa and Yuji Matsuzawa

Diabetes 2002 Jan; 51 (1): 114-123. https://doi.org/10.2337/diabetes.51.1.114

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Ghrelin Is Present in Pancreatic α-Cells of Humans and Rats and Stimulates Insulin Secretion
Yukari Date, Masamitsu Nakazato, Suzuko Hashiguchi, Katsuya Dezaki, Muhtashan S. Mondal, Hiroshi Hosoda, Masayasu Kojima, Kenji Kangawa, Terukatsu Arima, Hisayuki Matsuo, Toshihiko Yada and Shigeru Matsukura

Diabetes 2002 Jan; 51 (1): 124-129. https://doi.org/10.2337/diabetes.51.1.124

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Pathophysiology

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Basal Insulin Gene Expression Significantly Improves Conventional Insulin Therapy in Type 1 Diabetic Rats
Hengjiang Dong, Jennifer Altomonte, Nuria Morral, Marcia Meseck, Swan N. Thung and Savio L.C. Woo

Diabetes 2002 Jan; 51 (1): 130-138. https://doi.org/10.2337/diabetes.51.1.130

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Intrahepatic Mechanisms Underlying the Effect of Metformin in Decreasing Basal Glucose Production in Rats Fed a High-Fat Diet
Gilles Mithieux, Ludovic Guignot, Jean-Claude Bordet and Nicolas Wiernsperger

Diabetes 2002 Jan; 51 (1): 139-143. https://doi.org/10.2337/diabetes.51.1.139

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Insulin Resistance in Morbid ObesityReversal With Intramyocellular Fat Depletion
Aldo V. Greco, Gertrude Mingrone, Annalisa Giancaterini, Melania Manco, Manrico Morroni, Saverio Cinti, Marnie Granzotto, Roberto Vettor, Stefania Camastra and Ele Ferrannini

Diabetes 2002 Jan; 51 (1): 144-151. https://doi.org/10.2337/diabetes.51.1.144

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Chronic Central Melanocortin-4 Receptor Antagonism and Central Neuropeptide-Y Infusion in Rats Produce Increased Adiposity by Divergent Pathways
Katherine Baran, Elaine Preston, Donna Wilks, Gregory J. Cooney, Edward W. Kraegen and Amanda Sainsbury

Diabetes 2002 Jan; 51 (1): 152-158. https://doi.org/10.2337/diabetes.51.1.152

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Complication

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Hyperglycemia-Induced Apoptosis in Human Umbilical Vein Endothelial CellsInhibition by the AMP-Activated Protein Kinase Activation
Yasuo Ido, David Carling and Neil Ruderman

Diabetes 2002 Jan; 51 (1): 159-167. https://doi.org/10.2337/diabetes.51.1.159

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Leptin Effect on Endothelial Nitric Oxide Is Mediated Through Akt–Endothelial Nitric Oxide Synthase Phosphorylation Pathway
Carmine Vecchione, Angelo Maffei, Salvatore Colella, Alessandra Aretini, Roberta Poulet, Giacomo Frati, Maria Teresa Gentile, Luigi Fratta, Valentina Trimarco, Bruno Trimarco and Giuseppe Lembo

Diabetes 2002 Jan; 51 (1): 168-173. https://doi.org/10.2337/diabetes.51.1.168

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Overexpression of Metallothionein Reduces Diabetic Cardiomyopathy
Qiangrong Liang, Edward C. Carlson, Rajakumar V. Donthi, Patrica M. Kralik, Xia Shen and Paul N. Epstein

Diabetes 2002 Jan; 51 (1): 174-181. https://doi.org/10.2337/diabetes.51.1.174

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Autocrine Activation of the IGF-I Signaling Pathway in Mesangial Cells Isolated From Diabetic NOD Mice
Ivan Tack, Sharon J. Elliot, Mylene Potier, Ana Rivera, Gary E. Striker and Liliane J. Striker

Diabetes 2002 Jan; 51 (1): 182-188. https://doi.org/10.2337/diabetes.51.1.182

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The Effect of Dimethylbiguanide on Thrombin Activity, FXIII Activation, Fibrin Polymerization, and Fibrin Clot Formation
Kristina F. Standeven, Robert A.S. Ariëns, Paul Whitaker, Alison E. Ashcroft, John W. Weisel and Peter J. Grant

Diabetes 2002 Jan; 51 (1): 189-197. https://doi.org/10.2337/diabetes.51.1.189

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High Glucose via Peroxynitrite Causes Tyrosine Nitration and Inactivation of Prostacyclin Synthase That Is Associated With Thromboxane/Prostaglandin H₂ Receptor–Mediated Apoptosis and Adhesion Molecule Expression in Cultured Human Aortic Endothelial Cells
Ming-Hui Zou, Chaomei Shi and Richard A. Cohen

Diabetes 2002 Jan; 51 (1): 198-203. https://doi.org/10.2337/diabetes.51.1.198

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Epidemiology

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Predictability of Childhood Adiposity and Insulin for Developing Insulin Resistance Syndrome (Syndrome X) in Young AdulthoodThe Bogalusa Heart Study
Sathanur R. Srinivasan, Leann Myers and Gerald S. Berenson

Diabetes 2002 Jan; 51 (1): 204-209. https://doi.org/10.2337/diabetes.51.1.204

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High Familial Risk and Genetic Susceptibility in Early Onset Childhood Diabetes
Kathleen M. Gillespie, Edwin A.M. Gale and Polly J. Bingley

Diabetes 2002 Jan; 51 (1): 210-214. https://doi.org/10.2337/diabetes.51.1.210

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Congenic Mapping of the Diabetogenic Locus Idd4 to a 5.2-cM Region of Chromosome 11 in NOD MiceIdentification of Two Potential Candidate Subloci
Marsha Grattan, Qing-Sheng Mi, Craig Meagher and Terry L. Delovitch

Diabetes 2002 Jan; 51 (1): 215-223. https://doi.org/10.2337/diabetes.51.1.215

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PAX6 Mutation as a Genetic Factor Common to Aniridia and Glucose Intolerance
Tetsuyuki Yasuda, Yoshitaka Kajimoto, Yoshio Fujitani, Hirotaka Watada, Shuji Yamamoto, Takao Watarai, Yutaka Umayahara, Munehide Matsuhisa, Shin-ichi Gorogawa, Yasuaki Kuwayama, Yasuo Tano, Yoshimitsu Yamasaki and Masatsugu Hori

Diabetes 2002 Jan; 51 (1): 224-230. https://doi.org/10.2337/diabetes.51.1.224

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SNP43 of CAPN10 and the Risk of Type 2 Diabetes in African-AmericansThe Atherosclerosis Risk in Communities Study
Michael J. Garant, W.H. Linda Kao, Frederick Brancati, Josef Coresh, Tejal M. Rami, Craig L. Hanis, Eric Boerwinkle and Alan R. Shuldiner

Diabetes 2002 Jan; 51 (1): 231-237. https://doi.org/10.2337/diabetes.51.1.231

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Brief Genetics Report

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Chemokine Receptor Genotype Is Associated With Diabetic Nephropathy in Japanese With Type 2 Diabetes
Kunihiro Nakajima, Yasushi Tanaka, Takashi Nomiyama, Takeshi Ogihara, Lianshan Piao, Ken Sakai, Tomio Onuma and Ryuzo Kawamori

Diabetes 2002 Jan; 51 (1): 238-242. https://doi.org/10.2337/diabetes.51.1.238

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A Novel Homozygous Missense Mutation of Melanocortin-4 Receptor (MC4R) in a Japanese Woman With Severe Obesity
Hiromasa Kobayashi, Yoshihiro Ogawa, Mitsuyo Shintani, Ken Ebihara, Makiko Shimodahira, Toshio Iwakura, Megumu Hino, Takashi Ishihara, Katsuji Ikekubo, Hiroyuki Kurahachi and Kazuwa Nakao

Diabetes 2002 Jan; 51 (1): 243-246. https://doi.org/10.2337/diabetes.51.1.243

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Variation in the Calpain-10 Gene Affects Blood Glucose Levels in the British Population
Stephen Lynn, Julie C. Evans, Christopher White, Timothy M. Frayling, Andrew T. Hattersley, Doug M. Turnbull, Yukio Horikawa, Nancy J. Cox, Graeme I. Bell and Mark Walker

Diabetes 2002 Jan; 51 (1): 247-250. https://doi.org/10.2337/diabetes.51.1.247

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The Angiotensin-Converting Enzyme DD Genotype Is Associated With Glomerulopathy Lesions in Type 2 Diabetes
Anna Solini, Michele Dalla Vestra, Alois Saller, Romano Nosadini, Gaetano Crepaldi and Paola Fioretto

Diabetes 2002 Jan; 51 (1): 251-255. https://doi.org/10.2337/diabetes.51.1.251

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Erratum

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Erratum
Diabetes 2002 Jan; 51 (1): 256. https://doi.org/10.2337/diabetes.51.1.256

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Table of Contents

Rapid Publication

Banting Lecture 2001

Metabolism and Signal Transduction

Immunology and Transplantation

Islet Study

Pathophysiology

Complication

Epidemiology

Brief Genetics Report

Erratum

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