Intrahepatic Islet Transplantation in Type 1 Diabetic Patients Does Not Restore Hypoglycemic Hormonal Counterregulation or Symptom Recognition After Insulin Independence

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FIG. 5.
FIG. 5.

Symptom scores of islet transplant recipients (□), type 1 diabetic subjects ([cjs2113]), and nondiabetic control subjects ([cjs2110]) at basal and 45-min plasma glucose levels during the hypoglycemic clamp. The scores of the islet transplant recipients did not differ significantly from those of the type 1 diabetic subjects at all glycemic levels. At 40 mg/dl (2.2 mmol/l), symptom recognition in both groups was significantly less than that observed in the nondiabetic control subjects. *P < 0.05 vs. control, ANOVA.

This Article

  1. Diabetes vol. 51 no. 12 3428-3434