High White Blood Cell Count Is Associated With a Worsening of Insulin Sensitivity and Predicts the Development of Type 2 Diabetes

TABLE 2

Univariate relationships among markers of inflammation with selected anthropometric and metabolic characteristics (correlations by Spearman)

WBC Neutrophil count Lymphocyte count Monocyte count Eosinophil count Basophil count
n 352 209 209 209 209 209
Age −0.19* −0.05 −0.09 −0.05 −0.02 0.06
Body weight 0.27* 0.24 0.08 0.01 0.07 0.05
Body fat 0.31* 0.21 0.18 −0.18 0.09 0.06
Waist 0.29 0.27 0.08 −0.03 0.13 0.08
WTR 0.13 0.20 −0.02 0.05 0.03 0.23
Fasting glucose 0.05 0.07 0.04 −0.39* 0.02 0.11
Fasting insulin 0.28* 0.24* 0.19 −0.09 0.16 0.11
2-h glucose 0.12 0.08 0.01 −0.13 0.04 0.18
M-low −0.21* −0.11 −0.16 0.15 −0.13 0.01
M-high −0.13 −0.01 −0.06 0.23 −0.11 0.06
AIR (only NGT) 0.06 0.12 0.07 0.04 0.13 0.02
Basal EGO 0.07 0.05 0.04 0.18 0.12 0.06
  • Significant correlations are indicated as follows:

  • *

    * P < 0.001,

  • P < 0.01, and

  • P < 0.05. EGO, endogenous glucose output; WTR, waist-to-thigh ratio.

This Article

  1. Diabetes vol. 51 no. 2 455-461