Elevated Levels of Acute-Phase Proteins and Plasminogen Activator Inhibitor-1 Predict the Development of Type 2 Diabetes

TABLE 3

Logistic regression analysis for log PAI-1 with incident type 2 diabetes as the dependent variable stratified by diabetic status

Covariates NGT
IGT
OR (95% Cl) P value OR (95% Cl) P value
A. Demographic 2.42 (1.67–3.52) 0.0001 1.38 (1.03–1.83) 0.03
B. Demographic + fasting insulin 2.16 (1.46–3.20) 0.0001 1.31 (0.97–1.75) 0.07
C. Demographic + SI 2.13 (1.43–3.19) 0.0002 1.26 (0.94–1.70) 0.13
D. Demographic + BMI 2.14 (1.45–3.16) 0.0001 1.26 (0.93–1.71) 0.14
E. Demographic + waist 2.15 (1.44–3.21) 0.0002 1.34 (0.99–1.82) 0.06
F. “Extended model” 2.13 (1.29–3.54) 0.003 1.47 (0.98–2.21) 0.06
  • Demographic model (model A) includes as covariates age, sex, clinical center, and smoking. Extended model includes as covariates age, sex, clinical center, smoking, ethnicity, SI, BMI, family history of diabetes, and physical activity.

This Article

  1. Diabetes vol. 51 no. 4 1131-1137