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Table of Contents
February 2003; 52 (2)
Rapid Publications
Select this article
Kevin D. Niswender
,
Christopher D. Morrison
,
Deborah J. Clegg
,
Ryan Olson
,
Denis G. Baskin
,
Martin G. Myers, Jr.
,
Randy J. Seeley
,
and
Michael W. Schwartz
Insulin Activation of Phosphatidylinositol 3-Kinase in the Hypothalamic Arcuate Nucleus
:
A Key Mediator of Insulin-Induced Anorexia
Diabetes
February 2003
52
:
227
-
231
;
published ahead of print
December 6, 2002
,
doi:
10.2337/diabetes.52.2.227
Abstract
Full Text
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Perspectives in Diabetes
Select this article
Michael W. Schwartz
,
Stephen C. Woods
,
Randy J. Seeley
,
Gregory S. Barsh
,
Denis G. Baskin
,
and
Rudolph L. Leibel
Is the Energy Homeostasis System Inherently Biased Toward Weight Gain?
Diabetes
February 2003
52
:
232
-
238
;
doi:
10.2337/diabetes.52.2.232
Abstract
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Metabolism and Signal Transduction
Select this article
Otto Tschritter
,
Andreas Fritsche
,
Claus Thamer
,
Michael Haap
,
Fatemeh Shirkavand
,
Stefanie Rahe
,
Harald Staiger
,
Elke Maerker
,
Hans Häring
,
and
Michael Stumvoll
Plasma Adiponectin Concentrations Predict Insulin Sensitivity of Both Glucose and Lipid Metabolism
Diabetes
February 2003
52
:
239
-
243
;
doi:
10.2337/diabetes.52.2.239
Abstract
Full Text
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Alexandra Kautzky-Willer
,
Martin Krssak
,
Christine Winzer
,
Giovanni Pacini
,
Andrea Tura
,
Serdar Farhan
,
Oswald Wagner
,
Georg Brabant
,
Rüdiger Horn
,
Harald Stingl
,
Barbara Schneider
,
Werner Waldhäusl
,
and
Michael Roden
Increased Intramyocellular Lipid Concentration Identifies Impaired Glucose Metabolism in Women With Previous Gestational Diabetes
Diabetes
February 2003
52
:
244
-
251
;
doi:
10.2337/diabetes.52.2.244
Abstract
Full Text
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Younes Anini
and
Patricia L. Brubaker
Role of Leptin in the Regulation of Glucagon-Like Peptide-1 Secretion
Diabetes
February 2003
52
:
252
-
259
;
doi:
10.2337/diabetes.52.2.252
Abstract
Full Text
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Peter Staehr
,
Ole Hother-Nielsen
,
Bernard R. Landau
,
Visvanathan Chandramouli
,
Jens Juul Holst
,
and
Henning Beck-Nielsen
Effects of Free Fatty Acids Per Se on Glucose Production, Gluconeogenesis, and Glycogenolysis
Diabetes
February 2003
52
:
260
-
267
;
doi:
10.2337/diabetes.52.2.260
Abstract
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Obesity Studies
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Terry P. Combs
,
Anders H. Berg
,
Michael W. Rajala
,
Simon Klebanov
,
Puneeth Iyengar
,
José C. Jimenez-Chillaron
,
Mary Elizabeth Patti
,
Sabra L. Klein
,
Robert S. Weinstein
,
and
Philipp E. Scherer
Sexual Differentiation, Pregnancy, Calorie Restriction, and Aging Affect the Adipocyte-Specific Secretory Protein Adiponectin
Diabetes
February 2003
52
:
268
-
276
;
doi:
10.2337/diabetes.52.2.268
Abstract
Full Text
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Marc Gilbert
,
Christophe Magnan
,
Sophie Turban
,
Jocelyne André
,
and
Michèle Guerre-Millo
Leptin Receptor−Deficient Obese Zucker Rats Reduce Their Food Intake in Response to a Systemic Supply of Calories From Glucose
Diabetes
February 2003
52
:
277
-
282
;
doi:
10.2337/diabetes.52.2.277
Abstract
Full Text
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Kirsi A. Virtanen
,
Kirsti Hällsten
,
Riitta Parkkola
,
Tuula Janatuinen
,
Fredrik Lönnqvist
,
Tapio Viljanen
,
Tapani Rönnemaa
,
Juhani Knuuti
,
Risto Huupponen
,
Peter Lönnroth
,
and
Pirjo Nuutila
Differential Effects of Rosiglitazone and Metformin on Adipose Tissue Distribution and Glucose Uptake in Type 2 Diabetic Subjects
Diabetes
February 2003
52
:
283
-
290
;
doi:
10.2337/diabetes.52.2.283
Abstract
Full Text
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Mathieu Laplante
,
Henrike Sell
,
Karen L. MacNaul
,
Denis Richard
,
Joel P. Berger
,
and
Yves Deshaies
PPAR-γ Activation Mediates Adipose Depot−Specific Effects on Gene Expression and Lipoprotein Lipase Activity
:
Mechanisms for Modulation of Postprandial Lipemia and Differential Adipose Accretion
Diabetes
February 2003
52
:
291
-
299
;
doi:
10.2337/diabetes.52.2.291
Abstract
Full Text
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Kazuhisa Maeda
,
K. Teoman Uysal
,
Liza Makowski
,
Cem Z. Görgün
,
Genichi Atsumi
,
Rex A. Parker
,
Jens Brüning
,
Ann Vogel Hertzel
,
David A. Bernlohr
,
and
Gökhan S. Hotamisligil
Role of the Fatty Acid Binding Protein mal1 in Obesity and Insulin Resistance
Diabetes
February 2003
52
:
300
-
307
;
doi:
10.2337/diabetes.52.2.300
Abstract
Full Text
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Z. Elizabeth Floyd
and
Jacqueline M. Stephens
STAT5A Promotes Adipogenesis in Nonprecursor Cells and Associates With the Glucocorticoid Receptor During Adipocyte Differentiation
Diabetes
February 2003
52
:
308
-
314
;
doi:
10.2337/diabetes.52.2.308
Abstract
Full Text
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Katsunori Nonogaki
,
Luna Abdallah
,
Evan H. Goulding
,
Stephen J. Bonasera
,
and
Laurence H. Tecott
Hyperactivity and Reduced Energy Cost of Physical Activity in Serotonin 5-HT
2C
Receptor Mutant Mice
Diabetes
February 2003
52
:
315
-
320
;
doi:
10.2337/diabetes.52.2.315
Abstract
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Immunology and Transplantation
Select this article
Todd Pearson
,
Thomas G. Markees
,
Linda S. Wicker
,
David V. Serreze
,
Laurence B. Peterson
,
John P. Mordes
,
Aldo A. Rossini
,
and
Dale L. Greiner
NOD Congenic Mice Genetically Protected From Autoimmune Diabetes Remain Resistant to Transplantation Tolerance Induction
Diabetes
February 2003
52
:
321
-
326
;
doi:
10.2337/diabetes.52.2.321
Abstract
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Stuart P. Berzins
,
Emily S. Venanzi
,
Christophe Benoist
,
and
Diane Mathis
T-Cell Compartments of Prediabetic NOD Mice
Diabetes
February 2003
52
:
327
-
334
;
doi:
10.2337/diabetes.52.2.327
Abstract
Full Text
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Lut Overbergh
,
Brigitte Decallonne
,
Dumitru D. Branisteanu
,
Dirk Valckx
,
Ahmad Kasran
,
Roger Bouillon
,
and
Chantal Mathieu
Acute Shock Induced by Antigen Vaccination in NOD Mice
Diabetes
February 2003
52
:
335
-
341
;
doi:
10.2337/diabetes.52.2.335
Abstract
Full Text
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Govindarajan Rajagopalan
,
Yogish C. Kudva
,
Richard A. Flavell
,
and
Chella S. David
Accelerated Diabetes in Rat Insulin Promoter-Tumor Necrosis Factor-α Transgenic Nonobese Diabetic Mice Lacking Major Histocompatibility Class II Molecules
Diabetes
February 2003
52
:
342
-
347
;
doi:
10.2337/diabetes.52.2.342
Abstract
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Burak Kutlu
,
Martine I. Darville
,
Alessandra K. Cardozo
,
and
Décio L. Eizirik
Molecular Regulation of Monocyte Chemoattractant Protein-1 Expression in Pancreatic β-Cells
Diabetes
February 2003
52
:
348
-
355
;
doi:
10.2337/diabetes.52.2.348
Abstract
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Islet Studies
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Susanne G. Straub
,
Jennifer Mulvaney-Musa
,
Hiroki Yajima
,
Gregory A. Weiland
,
and
Geoffrey W.G. Sharp
Stimulation of Insulin Secretion by Denatonium, One of the Most Bitter-Tasting Substances Known
Diabetes
February 2003
52
:
356
-
364
;
doi:
10.2337/diabetes.52.2.356
Abstract
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Diva D. De León
,
Shaoping Deng
,
Reza Madani
,
Rexford S. Ahima
,
Daniel J. Drucker
,
and
Doris A. Stoffers
Role of Endogenous Glucagon-Like Peptide-1 in Islet Regeneration After Partial Pancreatectomy
Diabetes
February 2003
52
:
365
-
371
;
doi:
10.2337/diabetes.52.2.365
Abstract
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Rebecca L. Hull
,
Sofianos Andrikopoulos
,
C. Bruce Verchere
,
Josep Vidal
,
Feng Wang
,
Miriam Cnop
,
Ronald L. Prigeon
,
and
Steven E. Kahn
Increased Dietary Fat Promotes Islet Amyloid Formation and β-Cell Secretory Dysfunction in a Transgenic Mouse Model of Islet Amyloid
Diabetes
February 2003
52
:
372
-
379
;
doi:
10.2337/diabetes.52.2.372
Abstract
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Lise L. Kjems
,
Jens J. Holst
,
Aage Vølund
,
and
Sten Madsbad
The Influence of GLP-1 on Glucose-Stimulated Insulin Secretion
:
Effects on β-Cell Sensitivity in Type 2 and Nondiabetic Subjects
Diabetes
February 2003
52
:
380
-
386
;
doi:
10.2337/diabetes.52.2.380
Abstract
Full Text
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Suzanne Bertera
,
Megan L. Crawford
,
Angela M. Alexander
,
Glenn D. Papworth
,
Simon C. Watkins
,
Paul D. Robbins
,
and
Massimo Trucco
Gene Transfer of Manganese Superoxide Dismutase Extends Islet Graft Function in a Mouse Model of Autoimmune Diabetes
Diabetes
February 2003
52
:
387
-
393
;
doi:
10.2337/diabetes.52.2.387
Abstract
Full Text
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Nicolai M. Doliba
,
Marko Z. Vatamaniuk
,
Carol W. Buettger
,
Wei Qin
,
Heather W. Collins
,
Suzanne L. Wehrli
,
Richard D. Carr
,
and
Franz M. Matschinsky
Differential Effects of Glucose and Glyburide on Energetics and Na
+
Levels of βHC9 Cells
:
Nuclear Magnetic Resonance Spectroscopy and Respirometry Studies
Diabetes
February 2003
52
:
394
-
402
;
doi:
10.2337/diabetes.52.2.394
Abstract
Full Text
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J. Michael Moates
,
Sarmistha Nanda
,
Michelle A. Cissell
,
Ming-Jer Tsai
,
and
Roland Stein
BETA2
Activates Transcription From the Upstream Glucokinase Gene Promoter in Islet β-Cells and Gut Endocrine Cells
Diabetes
February 2003
52
:
403
-
408
;
doi:
10.2337/diabetes.52.2.403
Abstract
Full Text
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Tetsuro Izumi
,
Hiromi Yokota-Hashimoto
,
Shengli Zhao
,
Jie Wang
,
Philippe A. Halban
,
and
Toshiyuki Takeuchi
Dominant Negative Pathogenesis by Mutant Proinsulin in the Akita Diabetic Mouse
Diabetes
February 2003
52
:
409
-
416
;
doi:
10.2337/diabetes.52.2.409
Abstract
Full Text
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Alessandra Calabrese
,
Min Zhang
,
Véronique Serre-Beinier
,
David Caton
,
Christophe Mas
,
Leslie S. Satin
,
and
Paolo Meda
Connexin 36 Controls Synchronization of Ca
2+
Oscillations and Insulin Secretion in MIN6 Cells
Diabetes
February 2003
52
:
417
-
424
;
doi:
10.2337/diabetes.52.2.417
Abstract
Full Text
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Denny K.Y. Trinh
,
Kai Zhang
,
Moazzem Hossain
,
Patricia L. Brubaker
,
and
Daniel J. Drucker
Pax-6 Activates Endogenous Proglucagon Gene Expression in the Rodent Gastrointestinal Epithelium
Diabetes
February 2003
52
:
425
-
433
;
doi:
10.2337/diabetes.52.2.425
Abstract
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Pathophysiology
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Ellen Aasum
,
Anne D. Hafstad
,
David L. Severson
,
and
Terje S. Larsen
Age-Dependent Changes in Metabolism, Contractile Function, and Ischemic Sensitivity in Hearts From
db/db
Mice
Diabetes
February 2003
52
:
434
-
441
;
doi:
10.2337/diabetes.52.2.434
Abstract
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Gunnar Engström
,
Lars Stavenow
,
Bo Hedblad
,
Peter Lind
,
Karl-Fredrik Eriksson
,
Lars Janzon
,
and
Folke Lindgärde
Inflammation-Sensitive Plasma Proteins, Diabetes, and Mortality and Incidence of Myocardial Infarction and Stroke
:
A Population-Based Study
Diabetes
February 2003
52
:
442
-
447
;
doi:
10.2337/diabetes.52.2.442
Abstract
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Eiji Kimoto
,
Tetsuo Shoji
,
Kayo Shinohara
,
Masaaki Inaba
,
Yasuhisa Okuno
,
Takami Miki
,
Hidenori Koyama
,
Masanori Emoto
,
and
Yoshiki Nishizawa
Preferential Stiffening of Central Over Peripheral Arteries in Type 2 Diabetes
Diabetes
February 2003
52
:
448
-
452
;
doi:
10.2337/diabetes.52.2.448
Abstract
Full Text
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W. Timothy Garvey
,
Soonho Kwon
,
Deyi Zheng
,
Sara Shaughnessy
,
Penny Wallace
,
Amy Hutto
,
Kimberly Pugh
,
Alicia J. Jenkins
,
Richard L. Klein
,
and
Youlian Liao
Effects of Insulin Resistance and Type 2 Diabetes on Lipoprotein Subclass Particle Size and Concentration Determined by Nuclear Magnetic Resonance
Diabetes
February 2003
52
:
453
-
462
;
doi:
10.2337/diabetes.52.2.453
Abstract
Full Text
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Anthony J.G. Hanley
,
Ken Williams
,
Clicerio Gonzalez
,
Ralph B. D’Agostino, Jr
,
Lynne E. Wagenknecht
,
Michael P. Stern
,
and
Steven M. Haffner
Prediction of Type 2 Diabetes Using Simple Measures of Insulin Resistance
:
Combined Results From the San Antonio Heart Study, the Mexico City Diabetes Study, and the Insulin Resistance Atherosclerosis Study
Diabetes
February 2003
52
:
463
-
469
;
doi:
10.2337/diabetes.52.2.463
Abstract
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Riccardo C. Bonadonna
,
Michael Stumvoll
,
Andreas Fritsche
,
Michele Muggeo
,
Hans Häring
,
Enzo Bonora
,
and
Timon W. van Haeften
Altered Homeostatic Adaptation of First- and Second-Phase β-Cell Secretion in the Offspring of Patients With Type 2 Diabetes
:
Studies With a Minimal Model to Assess β-Cell Function
Diabetes
February 2003
52
:
470
-
480
;
doi:
10.2337/diabetes.52.2.470
Abstract
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Marianna Muranyi
,
Masayuki Fujioka
,
QingPing He
,
Angela Han
,
Gregory Yong
,
Katalin Csiszar
,
and
Ping-An Li
Diabetes Activates Cell Death Pathway After Transient Focal Cerebral Ischemia
Diabetes
February 2003
52
:
481
-
486
;
doi:
10.2337/diabetes.52.2.481
Abstract
Full Text
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Carol J. Homko
,
Peter Cheung
,
and
Guenther Boden
Effects of Free Fatty Acids on Glucose Uptake and Utilization in Healthy Women
Diabetes
February 2003
52
:
487
-
491
;
doi:
10.2337/diabetes.52.2.487
Abstract
Full Text
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Steven J. Hunter
,
Alison C. Boyd
,
Finbarr P.M. O’Harte
,
Aine M. McKillop
,
M. Ivan Wiggam
,
Mark H. Mooney
,
Jane T. McCluskey
,
John R. Lindsay
,
Cieran N. Ennis
,
Raymond Gamble
,
Brian Sheridan
,
Christopher R. Barnett
,
Helene McNulty
,
Patrick M. Bell
,
and
Peter R. Flatt
Demonstration of Glycated Insulin in Human Diabetic Plasma and Decreased Biological Activity Assessed by Euglycemic-Hyperinsulinemic Clamp Technique in Humans
Diabetes
February 2003
52
:
492
-
498
;
doi:
10.2337/diabetes.52.2.492
Abstract
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Complications
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Patrizio Odetti
,
Carlo Pesce
,
Nicola Traverso
,
Stefano Menini
,
Elena Pesce Maineri
,
Luana Cosso
,
Sabina Valentini
,
Stefania Patriarca
,
Damiano Cottalasso
,
Umberto M. Marinari
,
and
Maria Adelaide Pronzato
Comparative Trial of
N
-Acetyl-Cysteine, Taurine, and Oxerutin on Skin and Kidney Damage in Long-Term Experimental Diabetes
Diabetes
February 2003
52
:
499
-
505
;
doi:
10.2337/diabetes.52.2.499
Abstract
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Veronica Asnaghi
,
Chiara Gerhardinger
,
Todd Hoehn
,
Abidemi Adeboje
,
and
Mara Lorenzi
A Role for the Polyol Pathway in the Early Neuroretinal Apoptosis and Glial Changes Induced by Diabetes in the Rat
Diabetes
February 2003
52
:
506
-
511
;
doi:
10.2337/diabetes.52.2.506
Abstract
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Darren J. Kelly
,
Yuan Zhang
,
Claire Hepper
,
Renae M. Gow
,
Kassie Jaworski
,
Bruce E. Kemp
,
Jennifer L. Wilkinson-Berka
,
and
Richard E. Gilbert
Protein Kinase C β Inhibition Attenuates the Progression of Experimental Diabetic Nephropathy in the Presence of Continued Hypertension
Diabetes
February 2003
52
:
512
-
518
;
doi:
10.2337/diabetes.52.2.512
Abstract
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Malcolm Campbell
,
William E. Allen
,
Jonathan A. Silversides
,
and
Elisabeth R. Trimble
Glucose-Induced Phosphatidylinositol 3-Kinase and Mitogen-Activated Protein Kinase-Dependent Upregulation of the Platelet-Derived Growth Factor-β Receptor Potentiates Vascular Smooth Muscle Cell Chemotaxis
Diabetes
February 2003
52
:
519
-
526
;
doi:
10.2337/diabetes.52.2.519
Abstract
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Cora Weigert
,
Katrin Brodbeck
,
Frank C. Brosius III
,
Matthias Huber
,
Rainer Lehmann
,
Ulrich Friess
,
Sonia Facchin
,
Steffen Aulwurm
,
Hans U. Häring
,
Erwin D. Schleicher
,
and
Charles W. Heilig
Evidence for a Novel TGF-β1−Independent Mechanism of Fibronectin Production in Mesangial Cells Overexpressing Glucose Transporters
Diabetes
February 2003
52
:
527
-
535
;
doi:
10.2337/diabetes.52.2.527
Abstract
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Karin Ekberg
,
Tom Brismar
,
Bo-Lennart Johansson
,
Björn Jonsson
,
Per Lindström
,
and
John Wahren
Amelioration of Sensory Nerve Dysfunction by C-Peptide in Patients With Type 1 Diabetes
Diabetes
February 2003
52
:
536
-
541
;
doi:
10.2337/diabetes.52.2.536
Abstract
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Petra Algenstaedt
,
Christian Schaefer
,
Tanja Biermann
,
Andreas Hamann
,
Britta Schwarzloh
,
Heiner Greten
,
Wolfgang Rüther
,
and
Nils Hansen-Algenstaedt
Microvascular Alterations in Diabetic Mice Correlate With Level of Hyperglycemia
Diabetes
February 2003
52
:
542
-
549
;
doi:
10.2337/diabetes.52.2.542
Abstract
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Video Clips
Genetics
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Wen-Chi Hsueh
,
Pamela L. St. Jean
,
Braxton D. Mitchell
,
Toni I. Pollin
,
William C. Knowler
,
Margaret G. Ehm
,
Callum J. Bell
,
Hakan Sakul
,
Michael J. Wagner
,
Daniel K. Burns
,
and
Alan R. Shuldiner
Genome-Wide and Fine-Mapping Linkage Studies of Type 2 Diabetes and Glucose Traits in the Old Order Amish
:
Evidence for a New Diabetes Locus on Chromosome 14q11 and Confirmation of a Locus on Chromosome 1q21-q24
Diabetes
February 2003
52
:
550
-
557
;
doi:
10.2337/diabetes.52.2.550
Abstract
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Full Genome Scan
Brief Genetics Reports
Select this article
Agata Kubaszek
,
Jussi Pihlajamäki
,
Kari Punnonen
,
Pauli Karhapää
,
Ilkka Vauhkonen
,
and
Markku Laakso
The C-174G Promoter Polymorphism of the IL-6 Gene Affects Energy Expenditure and Insulin Sensitivity
Diabetes
February 2003
52
:
558
-
561
;
doi:
10.2337/diabetes.52.2.558
Abstract
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Haruhiko Osawa
,
Hiroshi Onuma
,
Akiko Murakami
,
Masaaki Ochi
,
Tatsuya Nishimiya
,
Kenichi Kato
,
Ikki Shimizu
,
Yasuhisa Fujii
,
Jun Ohashi
,
and
Hideichi Makino
Systematic Search for Single Nucleotide Polymorphisms in the FOXC2 Gene
:
The Absence of Evidence for the Association of Three Frequent Single Nucleotide Polymorphisms and Four Common Haplotypes With Japanese Type 2 Diabetes
Diabetes
February 2003
52
:
562
-
567
;
doi:
10.2337/diabetes.52.2.562
Abstract
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Anna L. Gloyn
,
Michael N. Weedon
,
Katharine R. Owen
,
Martina J. Turner
,
Bridget A. Knight
,
Graham Hitman
,
Mark Walker
,
Jonathan C. Levy
,
Mike Sampson
,
Stephanie Halford
,
Mark I. McCarthy
,
Andrew T. Hattersley
,
and
Timothy M. Frayling
Large-Scale Association Studies of Variants in Genes Encoding the Pancreatic β-Cell K
ATP
Channel Subunits Kir6.2 (
KCNJ11
) and SUR1 (
ABCC8
) Confirm That the
KCNJ11
E23K Variant Is Associated With Type 2 Diabetes
Diabetes
February 2003
52
:
568
-
572
;
doi:
10.2337/diabetes.52.2.568
Abstract
Full Text
Full Text (PDF)
Select this article
Eva-Maria D. Nielsen
,
Lars Hansen
,
Bendix Carstensen
,
Søren M. Echwald
,
Thomas Drivsholm
,
Charlotte Glümer
,
Birger Thorsteinsson
,
Knut Borch-Johnsen
,
Torben Hansen
,
and
Oluf Pedersen
The E23K Variant of Kir6.2 Associates With Impaired Post-OGTT Serum Insulin Response and Increased Risk of Type 2 Diabetes
Diabetes
February 2003
52
:
573
-
577
;
doi:
10.2337/diabetes.52.2.573
Abstract
Full Text
Full Text (PDF)
Erratum
Select this article
Errata
Diabetes
February 2003
52
:
578
;
doi:
10.2337/diabetes.52.2.578
Extract
Full Text
Full Text (PDF)
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February 2003;
52
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