Table of Contents

Perspectives in Diabetes

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- Michael Stumvoll,
- P. Antonio Tataranni,
- Norbert Stefan,
- Barbora Vozarova,
- and Clifton Bogardus
Glucose Allostasis
Diabetes April 2003 52:903-909; doi:10.2337/diabetes.52.4.903

Metabolism and Signal Transduction

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- David B. Savage,
- Garry D. Tan,
- Carlo L. Acerini,
- Susan A. Jebb,
- Maura Agostini,
- Mark Gurnell,
- Rachel L. Williams,
- A. Margot Umpleby,
- E. Louise Thomas,
- Jimmy D. Bell,
- Adrian K. Dixon,
- Fidelma Dunne,
- Romina Boiani,
- Saverio Cinti,
- Antonio Vidal-Puig,
- Fredrik Karpe,
- V. Krishna K. Chatterjee,
- and Stephen O’Rahilly
Human Metabolic Syndrome Resulting From Dominant-Negative Mutations in the Nuclear Receptor Peroxisome Proliferator-Activated Receptor-γ
Diabetes April 2003 52:910-917; doi:10.2337/diabetes.52.4.910
Select this article
- Hans J. Woerle,
- Peter R. Mariuz,
- Christian Meyer,
- Richard C. Reichman,
- Emilia M. Popa,
- Jean M. Dostou,
- Stephen L. Welle,
- and John E. Gerich
Mechanisms for the Deterioration in Glucose Tolerance Associated With HIV Protease Inhibitor Regimens
Diabetes April 2003 52:918-925; doi:10.2337/diabetes.52.4.918
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- Sean L. McGee,
- Kirsten F. Howlett,
- Rebecca L. Starkie,
- David Cameron-Smith,
- Bruce E. Kemp,
- and Mark Hargreaves
Exercise Increases Nuclear AMPK α₂ in Human Skeletal Muscle
Diabetes April 2003 52:926-928; doi:10.2337/diabetes.52.4.926
Select this article
- Yuan Gao,
- Ken Walder,
- Terry Sunderland,
- Lakshmi Kantham,
- Helen C. Feng,
- Melissa Quick,
- Natalie Bishara,
- Andrea de Silva,
- Guy Augert,
- Janette Tenne-Brown,
- and Gregory R. Collier
Elevation in Tanis Expression Alters Glucose Metabolism and Insulin Sensitivity in H4IIE Cells
Diabetes April 2003 52:929-934; doi:10.2337/diabetes.52.4.929
Select this article
- Joseph T. Brozinick, Jr,
- Brian R. Roberts,
- and G. Lynis Dohm
Defective Signaling Through Akt-2 and -3 But Not Akt-1 in Insulin-Resistant Human Skeletal Muscle: Potential Role in Insulin Resistance
Diabetes April 2003 52:935-941; doi:10.2337/diabetes.52.4.935
Select this article
- Stefan Engeli,
- Mareike Feldpausch,
- Kerstin Gorzelniak,
- Frauke Hartwig,
- Ute Heintze,
- Jürgen Janke,
- Matthias Möhlig,
- Andreas F.H. Pfeiffer,
- Friedrich C. Luft,
- and Arya M. Sharma
Association Between Adiponectin and Mediators of Inflammation in Obese Women
Diabetes April 2003 52:942-947; doi:10.2337/diabetes.52.4.942
Select this article
- Daisuke Kohno,
- Hong-Zhi Gao,
- Shinji Muroya,
- Sakae Kikuyama,
- and Toshihiko Yada
Ghrelin Directly Interacts With Neuropeptide-Y-Containing Neurons in the Rat Arcuate Nucleus: Ca²⁺ Signaling via Protein Kinase A and N-Type Channel-Dependent Mechanisms and Cross-Talk With Leptin and Orexin
Diabetes April 2003 52:948-956; doi:10.2337/diabetes.52.4.948

Immunology and Transplantation

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- R. Damaris Molano,
- Antonello Pileggi,
- Thierry Berney,
- Raffaella Poggioli,
- Elsie Zahr,
- Robert Oliver,
- Camillo Ricordi,
- David M. Rothstein,
- Giacomo P. Basadonna,
- and Luca Inverardi
Prolonged Islet Allograft Survival in Diabetic NOD Mice by Targeting CD45RB and CD154
Diabetes April 2003 52:957-964; doi:10.2337/diabetes.52.4.957

Islet Studies

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- Bumsup Lee,
- Philip D. Miles,
- Leonardo Vargas,
- Peng Luan,
- Susan Glasco,
- Yulia Kushnareva,
- Elisabeth S. Kornbrust,
- Kathryn A. Grako,
- Claes B. Wollheim,
- Pierre Maechler,
- Jerrold M. Olefsky,
- and Christen M. Anderson
Inhibition of Mitochondrial Na⁺-Ca²⁺ Exchanger Increases Mitochondrial Metabolism and Potentiates Glucose-Stimulated Insulin Secretion in Rat Pancreatic Islets
Diabetes April 2003 52:965-973; doi:10.2337/diabetes.52.4.965
Select this article
- Isabelle Briaud,
- Melissa K. Lingohr,
- Lorna M. Dickson,
- Christian E. Wrede,
- and Christopher J. Rhodes
Differential Activation Mechanisms of Erk-1/2 and p70^S6K by Glucose in Pancreatic β-Cells
Diabetes April 2003 52:974-983; doi:10.2337/diabetes.52.4.974
Select this article
- Malathi Srinivasan,
- Ravikumar Aalinkeel,
- Fei Song,
- and Mulchand S. Patel
Programming of Islet Functions in the Progeny of Hyperinsulinemic/Obese Rats
Diabetes April 2003 52:984-990; doi:10.2337/diabetes.52.4.984
Select this article
- Katrin Eitel,
- Harald Staiger,
- Johannes Rieger,
- Harald Mischak,
- Heide Brandhorst,
- Mathias D. Brendel,
- Reinhard G. Bretzel,
- Hans-Ulrich Häring,
- and Monika Kellerer
Protein Kinase C δ Activation and Translocation to the Nucleus Are Required for Fatty Acid-Induced Apoptosis of Insulin-Secreting Cells
Diabetes April 2003 52:991-997; doi:10.2337/diabetes.52.4.991
Select this article
- Gil Leibowitz,
- Andrei I. Oprescu,
- Gökhan Üçkaya,
- David J. Gross,
- Erol Cerasi,
- and Nurit Kaiser
Insulin Does Not Mediate Glucose Stimulation of Proinsulin Biosynthesis
Diabetes April 2003 52:998-1003; doi:10.2337/diabetes.52.4.998
Select this article
- Anna Abella,
- Luc Marti,
- Marta Camps,
- Marc Claret,
- J. Fernández-Alvarez,
- Ramon Gomis,
- Anna Gumà,
- Nathalie Viguerie,
- Christian Carpéné,
- Manuel Palacín,
- Xavier Testar,
- and Antonio Zorzano
Semicarbazide-Sensitive Amine Oxidase/Vascular Adhesion Protein-1 Activity Exerts an Antidiabetic Action in Goto-Kakizaki Rats
Diabetes April 2003 52:1004-1013; doi:10.2337/diabetes.52.4.1004

Complications

Select this article
- D. Steven Zatechka, Jr,
- Peter F. Kador,
- Sixto Garcia-Castiñeiras,
- and Marjorie F. Lou
Diabetes Can Alter the Signal Transduction Pathways in the Lens of Rats
Diabetes April 2003 52:1014-1022; doi:10.2337/diabetes.52.4.1014
Select this article
- Sophie Doublier,
- Gennaro Salvidio,
- Enrico Lupia,
- Vesa Ruotsalainen,
- Daniela Verzola,
- Giacomo Deferrari,
- and Giovanni Camussi
Nephrin Expression Is Reduced in Human Diabetic Nephropathy: Evidence for a Distinct Role for Glycated Albumin and Angiotensin II
Diabetes April 2003 52:1023-1030; doi:10.2337/diabetes.52.4.1023
Select this article
- Michele Dalla Vestra,
- Alessandra Masiero,
- Anna Maria Roiter,
- Alois Saller,
- Gaetano Crepaldi,
- and Paola Fioretto
Is Podocyte Injury Relevant in Diabetic Nephropathy?: Studies in Patients With Type 2 Diabetes
Diabetes April 2003 52:1031-1035; doi:10.2337/diabetes.52.4.1031
Select this article
- M. Luiza Caramori,
- Paola Fioretto,
- and Michael Mauer
Low Glomerular Filtration Rate in Normoalbuminuric Type 1 Diabetic Patients: An Indicator of More Advanced Glomerular Lesions
Diabetes April 2003 52:1036-1040; doi:10.2337/diabetes.52.4.1036
Select this article
- Bijukumar Gopalkrishnapillai,
- Vigneshwaran Nadanathangam,
- Nivedita Karmakar,
- Sneh Anand,
- and Anoop Misra
Evaluation of Autofluorescent Property of Hemoglobin-Advanced Glycation End Product as a Long-Term Glycemic Index of Diabetes
Diabetes April 2003 52:1041-1046; doi:10.2337/diabetes.52.4.1041

Genetics

Select this article
- Barbara A. Gower,
- José R. Fernández,
- T. Mark Beasley,
- Mark D. Shriver,
- and Michael I. Goran
Using Genetic Admixture to Explain Racial Differences in Insulin-Related Phenotypes
Diabetes April 2003 52:1047-1051; doi:10.2337/diabetes.52.4.1047

Brief Genetics Reports

Select this article
- Valma Hyttinen,
- Jaakko Kaprio,
- Leena Kinnunen,
- Markku Koskenvuo,
- and Jaakko Tuomilehto
Genetic Liability of Type 1 Diabetes and the Onset Age Among 22,650 Young Finnish Twin Pairs: A Nationwide Follow-Up Study
Diabetes April 2003 52:1052-1055; doi:10.2337/diabetes.52.4.1052

Perspectives in Diabetes

Glucose Allostasis

Metabolism and Signal Transduction

Human Metabolic Syndrome Resulting From Dominant-Negative Mutations in the Nuclear Receptor Peroxisome Proliferator-Activated Receptor-γ

Mechanisms for the Deterioration in Glucose Tolerance Associated With HIV Protease Inhibitor Regimens

Exercise Increases Nuclear AMPK α₂ in Human Skeletal Muscle

Elevation in Tanis Expression Alters Glucose Metabolism and Insulin Sensitivity in H4IIE Cells

Defective Signaling Through Akt-2 and -3 But Not Akt-1 in Insulin-Resistant Human Skeletal Muscle: Potential Role in Insulin Resistance

Association Between Adiponectin and Mediators of Inflammation in Obese Women

Ghrelin Directly Interacts With Neuropeptide-Y-Containing Neurons in the Rat Arcuate Nucleus: Ca²⁺ Signaling via Protein Kinase A and N-Type Channel-Dependent Mechanisms and Cross-Talk With Leptin and Orexin

Immunology and Transplantation

Prolonged Islet Allograft Survival in Diabetic NOD Mice by Targeting CD45RB and CD154

Islet Studies

Inhibition of Mitochondrial Na⁺-Ca²⁺ Exchanger Increases Mitochondrial Metabolism and Potentiates Glucose-Stimulated Insulin Secretion in Rat Pancreatic Islets

Differential Activation Mechanisms of Erk-1/2 and p70^S6K by Glucose in Pancreatic β-Cells

Programming of Islet Functions in the Progeny of Hyperinsulinemic/Obese Rats

Protein Kinase C δ Activation and Translocation to the Nucleus Are Required for Fatty Acid-Induced Apoptosis of Insulin-Secreting Cells

Insulin Does Not Mediate Glucose Stimulation of Proinsulin Biosynthesis

Semicarbazide-Sensitive Amine Oxidase/Vascular Adhesion Protein-1 Activity Exerts an Antidiabetic Action in Goto-Kakizaki Rats

Complications

Diabetes Can Alter the Signal Transduction Pathways in the Lens of Rats

Nephrin Expression Is Reduced in Human Diabetic Nephropathy: Evidence for a Distinct Role for Glycated Albumin and Angiotensin II

Is Podocyte Injury Relevant in Diabetic Nephropathy?: Studies in Patients With Type 2 Diabetes

Low Glomerular Filtration Rate in Normoalbuminuric Type 1 Diabetic Patients: An Indicator of More Advanced Glomerular Lesions

Evaluation of Autofluorescent Property of Hemoglobin-Advanced Glycation End Product as a Long-Term Glycemic Index of Diabetes

Genetics

Using Genetic Admixture to Explain Racial Differences in Insulin-Related Phenotypes

Brief Genetics Reports

Genetic Liability of Type 1 Diabetes and the Onset Age Among 22,650 Young Finnish Twin Pairs: A Nationwide Follow-Up Study

This Issue

Current Issue

Table of Contents

Perspectives in Diabetes

Glucose Allostasis

Metabolism and Signal Transduction

Human Metabolic Syndrome Resulting From Dominant-Negative Mutations in the Nuclear Receptor Peroxisome Proliferator-Activated Receptor-γ

Mechanisms for the Deterioration in Glucose Tolerance Associated With HIV Protease Inhibitor Regimens

Exercise Increases Nuclear AMPK α2 in Human Skeletal Muscle

Elevation in Tanis Expression Alters Glucose Metabolism and Insulin Sensitivity in H4IIE Cells

Defective Signaling Through Akt-2 and -3 But Not Akt-1 in Insulin-Resistant Human Skeletal Muscle: Potential Role in Insulin Resistance

Association Between Adiponectin and Mediators of Inflammation in Obese Women

Ghrelin Directly Interacts With Neuropeptide-Y-Containing Neurons in the Rat Arcuate Nucleus: Ca2+ Signaling via Protein Kinase A and N-Type Channel-Dependent Mechanisms and Cross-Talk With Leptin and Orexin

Immunology and Transplantation

Prolonged Islet Allograft Survival in Diabetic NOD Mice by Targeting CD45RB and CD154

Islet Studies

Inhibition of Mitochondrial Na+-Ca2+ Exchanger Increases Mitochondrial Metabolism and Potentiates Glucose-Stimulated Insulin Secretion in Rat Pancreatic Islets

Differential Activation Mechanisms of Erk-1/2 and p70S6K by Glucose in Pancreatic β-Cells

Programming of Islet Functions in the Progeny of Hyperinsulinemic/Obese Rats

Protein Kinase C δ Activation and Translocation to the Nucleus Are Required for Fatty Acid-Induced Apoptosis of Insulin-Secreting Cells

Insulin Does Not Mediate Glucose Stimulation of Proinsulin Biosynthesis

Semicarbazide-Sensitive Amine Oxidase/Vascular Adhesion Protein-1 Activity Exerts an Antidiabetic Action in Goto-Kakizaki Rats

Complications

Diabetes Can Alter the Signal Transduction Pathways in the Lens of Rats

Nephrin Expression Is Reduced in Human Diabetic Nephropathy: Evidence for a Distinct Role for Glycated Albumin and Angiotensin II

Is Podocyte Injury Relevant in Diabetic Nephropathy?: Studies in Patients With Type 2 Diabetes

Low Glomerular Filtration Rate in Normoalbuminuric Type 1 Diabetic Patients: An Indicator of More Advanced Glomerular Lesions

Evaluation of Autofluorescent Property of Hemoglobin-Advanced Glycation End Product as a Long-Term Glycemic Index of Diabetes

Genetics

Using Genetic Admixture to Explain Racial Differences in Insulin-Related Phenotypes

Brief Genetics Reports

Genetic Liability of Type 1 Diabetes and the Onset Age Among 22,650 Young Finnish Twin Pairs: A Nationwide Follow-Up Study

This Issue

Current Issue

Exercise Increases Nuclear AMPK α₂ in Human Skeletal Muscle

Ghrelin Directly Interacts With Neuropeptide-Y-Containing Neurons in the Rat Arcuate Nucleus: Ca²⁺ Signaling via Protein Kinase A and N-Type Channel-Dependent Mechanisms and Cross-Talk With Leptin and Orexin

Inhibition of Mitochondrial Na⁺-Ca²⁺ Exchanger Increases Mitochondrial Metabolism and Potentiates Glucose-Stimulated Insulin Secretion in Rat Pancreatic Islets

Differential Activation Mechanisms of Erk-1/2 and p70^S6K by Glucose in Pancreatic β-Cells