Glycation Inactivation of the Complement Regulatory Protein CD59

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

FIG. 1.
FIG. 1.

MAC deposition in diabetic nephropathy. MAC deposition was found in the glomeruli and middle-size arteries of a kidney that was transplanted into a diabetic patient (B) but not in a biopsy sample of minimal-change nephropathy stained simultaneously (A). The white and red arrows, respectively, show glomeruli and blood vessels. MAC deposition in diabetic (D and E) but not in nondiabetic (C) nephropathy in archival samples of renal biopsies stained with anti-MAC antibodies. Arrows, MAC deposition.

This Article

  1. Diabetes vol. 53 no. 10 2653-2661