Glycation Inactivation of the Complement Regulatory Protein CD59
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Glycated hCD59 colocalizes with MAC in diabetic human nerves. Serial sections of a diabetic (D) and a nondiabetic (ND) nerve
were stained with anti-MAC or anti–glycated hCD59 antibodies. Staining with anti–ulex Europaeus agglutinin-I antibody shows
the endoneurial microvessels (arrows in the nondiabetic sample). All pictures were taken at ×20; the squares delineate the
region amplified in the inset. Magnification ×20; ×60 in inset.