Glycation Inactivation of the Complement Regulatory Protein CD59

TABLE 1

Clinical characteristics of 12 patients with diabetic nephropathy

Patient no. Sex Age (years) Plasma creatinine (mg/dl) Proteinuria (mg/24 h) Pathology
1 F 66 2.5 11 Diffuse intracapillary glomerulosclerosis with interstitial fibrosis
2 F 59 2.0 13 Glomerulosclerosis with nodule formation
3 F 55 5 2.5 Advance diffuse and nodular glomerulosclerosis
4 M 77 2.9 423 Diffuse and nodular diabetic glomerulosclerosis
5 F 52 N/A N/A Diffuse and nodular diabetic glomerulosclerosis moderately advanced
6 F 45 N/A N/A Diffuse mesangial sclerosis
7 M 55 3.5 170 Diffuse intracapillary glomerulosclerosis with priminent hyaline arteriolar sclerosis
8 M 59 1.8 233 Diffuse and nodular diabetic glomerulosclerosis moderately advanced
9 F 50 N/A N/A Intracapillar glomerulosclerosis with interstitial fibrosis
10 M 71 2.7 >55 Advanced diffuse and nodular glomerulosclerosis
11 M 62 1.8 233 Diffuse intracapillar glomerulosclerosis
12 F 46 2.3 >300 Glomerulosclerosis with interstitial fibrosis
13 N/A N/A N/A N/A N/A

This Article

  1. Diabetes vol. 53 no. 10 2653-2661