Table of Contents

Banting Lecture 2003

Select this article
- Aldo A. Rossini
Autoimmune Diabetes and the Circle of Tolerance
Diabetes February 2004 53:267-275; doi:10.2337/diabetes.53.2.267

Perspectives in Diabetes

Select this article
- Douglas R. Seals and
- Christopher Bell
Chronic Sympathetic Activation: Consequence and Cause of Age-Associated Obesity?
Diabetes February 2004 53:276-284; doi:10.2337/diabetes.53.2.276

Metabolism

Select this article
- Raul C. Camacho,
- R. Richard Pencek,
- D. Brooks Lacy,
- Freyja D. James,
- and David H. Wasserman
Suppression of Endogenous Glucose Production by Mild Hyperinsulinemia During Exercise Is Determined Predominantly by Portal Venous Insulin
Diabetes February 2004 53:285-293; doi:10.2337/diabetes.53.2.285
Select this article
- Mads K. Holten,
- Morten Zacho,
- Michael Gaster,
- Carsten Juel,
- Jørgen F.P. Wojtaszewski,
- and Flemming Dela
Strength Training Increases Insulin-Mediated Glucose Uptake, GLUT4 Content, and Insulin Signaling in Skeletal Muscle in Patients With Type 2 Diabetes
Diabetes February 2004 53:294-305; doi:10.2337/diabetes.53.2.294
Select this article
- Patrick T. Fueger,
- Deanna P. Bracy,
- Carlo M. Malabanan,
- R. Richard Pencek,
- Daryl K. Granner,
- and David H. Wasserman
Hexokinase II Overexpression Improves Exercise-Stimulated But Not Insulin-Stimulated Muscle Glucose Uptake in High-Fat-Fed C57BL/6J Mice
Diabetes February 2004 53:306-314; doi:10.2337/diabetes.53.2.306
Select this article
- Yuichiro Nishida,
- Kumpei Tokuyama,
- Shoichiro Nagasaka,
- Yasuki Higaki,
- Yoko Shirai,
- Akira Kiyonaga,
- Munehiro Shindo,
- Ikuyo Kusaka,
- Tomoatsu Nakamura,
- Shun Ishibashi,
- and Hiroaki Tanaka
Effect of Moderate Exercise Training on Peripheral Glucose Effectiveness, Insulin Sensitivity, and Endogenous Glucose Production in Healthy Humans Estimated by a Two-Compartment-Labeled Minimal Model
Diabetes February 2004 53:315-320; doi:10.2337/diabetes.53.2.315

Signal Transduction

Select this article
- Yvan Gosmain,
- Etienne Lefai,
- Stephan Ryser,
- Marina Roques,
- and Hubert Vidal
Sterol Regulatory Element-Binding Protein-1 Mediates the Effect of Insulin on Hexokinase II Gene Expression in Human Muscle Cells
Diabetes February 2004 53:321-329; doi:10.2337/diabetes.53.2.321
Select this article
- David C. Wright,
- Kathleen A. Hucker,
- John O. Holloszy,
- and Dong Ho Han
Ca²⁺ and AMPK Both Mediate Stimulation of Glucose Transport by Muscle Contractions
Diabetes February 2004 53:330-335; doi:10.2337/diabetes.53.2.330

Obesity Study

Select this article
- Li-Jun Ma,
- Su-Li Mao,
- Kevin L. Taylor,
- Talerngsak Kanjanabuch,
- YouFei Guan,
- YaHua Zhang,
- Nancy J. Brown,
- Larry L. Swift,
- Owen P. McGuinness,
- David H. Wasserman,
- Douglas E. Vaughan,
- and Agnes B. Fogo
Prevention of Obesity and Insulin Resistance in Mice Lacking Plasminogen Activator Inhibitor 1
Diabetes February 2004 53:336-346; doi:10.2337/diabetes.53.2.336
Select this article
- Coralia Pérez,
- Carmen Fernández-Galaz,
- Teresa Fernández-Agulló,
- Carmen Arribas,
- Antonio Andrés,
- Manuel Ros,
- and José M. Carrascosa
Leptin Impairs Insulin Signaling in Rat Adipocytes
Diabetes February 2004 53:347-353; doi:10.2337/diabetes.53.2.347

Immunology and Transplantation

Select this article
- Aziz Alami Chentoufi,
- Michael Palumbo,
- and Constantin Polychronakos
Proinsulin Expression by Hassall’s Corpuscles in the Mouse Thymus
Diabetes February 2004 53:354-359; doi:10.2337/diabetes.53.2.354
Select this article
- Abdulkadir Omer,
- Valérie F. Duvivier-Kali,
- William Aschenbach,
- Vaja Tchipashvili,
- Laurie J. Goodyear,
- and Gordon C. Weir
Exercise Induces Hypoglycemia in Rats With Islet Transplantation
Diabetes February 2004 53:360-365; doi:10.2337/diabetes.53.2.360
Select this article
- Sarah E. Eckenrode,
- Qingguo Ruan,
- Ping Yang,
- Weipeng Zheng,
- Richard A. McIndoe,
- and Jin-Xiong She
Gene Expression Profiles Define a Key Checkpoint for Type 1 Diabetes in NOD Mice
Diabetes February 2004 53:366-375; doi:10.2337/diabetes.53.2.366
Select this article
- Boris Nikolic,
- Yasuo Takeuchi,
- Igor Leykin,
- Yasuhiro Fudaba,
- R. Neal Smith,
- and Megan Sykes
Mixed Hematopoietic Chimerism Allows Cure of Autoimmune Diabetes Through Allogeneic Tolerance and Reversal of Autoimmunity
Diabetes February 2004 53:376-383; doi:10.2337/diabetes.53.2.376
Select this article
- Peter Achenbach,
- Katharina Warncke,
- Jürgen Reiter,
- Heike E. Naserke,
- Alistair J.K. Williams,
- Polly J. Bingley,
- Ezio Bonifacio,
- and Anette-G. Ziegler
Stratification of Type 1 Diabetes Risk on the Basis of Islet Autoantibody Characteristics
Diabetes February 2004 53:384-392; doi:10.2337/diabetes.53.2.384

Islet Studies

Select this article
- Kathryn J. Mitchell,
- Takashi Tsuboi,
- and Guy A. Rutter
Role for Plasma Membrane-Related Ca²⁺-ATPase-1 (ATP2C1) in Pancreatic β-Cell Ca²⁺ Homeostasis Revealed by RNA Silencing
Diabetes February 2004 53:393-400; doi:10.2337/diabetes.53.2.393
Select this article
- Ian R. Sweet,
- Daniel L. Cook,
- Eric DeJulio,
- Angela R. Wallen,
- Gamal Khalil,
- James Callis,
- and JoAnna Reems
Regulation of ATP/ADP in Pancreatic Islets
Diabetes February 2004 53:401-409; doi:10.2337/diabetes.53.2.401

Pathophysiology

Select this article
- Yin Liang,
- Melville C. Osborne,
- Brett P. Monia,
- Sanjay Bhanot,
- William A. Gaarde,
- Chantal Reed,
- Pengxiang She,
- Thomas L. Jetton,
- and Keith T. Demarest
Reduction in Glucagon Receptor Expression by an Antisense Oligonucleotide Ameliorates Diabetic Syndrome in db/db Mice
Diabetes February 2004 53:410-417; doi:10.2337/diabetes.53.2.410
Select this article
- Ewan C. McNay and
- Robert S. Sherwin
Effect of Recurrent Hypoglycemia on Spatial Cognition and Cognitive Metabolism in Normal and Diabetic Rats
Diabetes February 2004 53:418-425; doi:10.2337/diabetes.53.2.418
Select this article
- Chynna Steele,
- William A. Hagopian,
- Stephen Gitelman,
- Umesh Masharani,
- Melissa Cavaghan,
- Kristina I. Rother,
- David Donaldson,
- David M. Harlan,
- Jeffrey Bluestone,
- and Kevan C. Herold
Insulin Secretion in Type 1 Diabetes
Diabetes February 2004 53:426-433; doi:10.2337/diabetes.53.2.426
Select this article
- Peter M. Okin,
- Richard B. Devereux,
- Elisa T. Lee,
- James M. Galloway,
- and Barbara V. Howard
Electrocardiographic Repolarization Complexity and Abnormality Predict All-Cause and Cardiovascular Mortality in Diabetes: The Strong Heart Study
Diabetes February 2004 53:434-440; doi:10.2337/diabetes.53.2.434
Select this article
- Radhika Muzumdar,
- Xiaohui Ma,
- Gil Atzmon,
- Patricia Vuguin,
- Xiaoman Yang,
- and Nir Barzilai
Decrease in Glucose-Stimulated Insulin Secretion With Aging Is Independent of Insulin Action
Diabetes February 2004 53:441-446; doi:10.2337/diabetes.53.2.441
Select this article
- Lei Zhang,
- Michelle A. Vincent,
- Stephen M. Richards,
- Lucy H. Clerk,
- Stephen Rattigan,
- Michael G. Clark,
- and Eugene J. Barrett
Insulin Sensitivity of Muscle Capillary Recruitment In Vivo
Diabetes February 2004 53:447-453; doi:10.2337/diabetes.53.2.447

Complication

Select this article
- Raffaele Marfella,
- Clara Di Filippo,
- Katherine Esposito,
- Francesco Nappo,
- Elena Piegari,
- Salvatore Cuzzocrea,
- Liberato Berrino,
- Francesco Rossi,
- Dario Giugliano,
- and Michele D’Amico
Absence of Inducible Nitric Oxide Synthase Reduces Myocardial Damage During Ischemia Reperfusion in Streptozotocin-Induced Hyperglycemic Mice
Diabetes February 2004 53:454-462; doi:10.2337/diabetes.53.2.454
Select this article
- Keshore R. Bidasee,
- Yinong Zhang,
- Chun Hong Shao,
- Mu Wang,
- Kaushik P. Patel,
- Ü. Deniz Dincer,
- and Henry R. Besch
Diabetes Increases Formation of Advanced Glycation End Products on Sarco(endo)plasmic Reticulum Ca²⁺-ATPase
Diabetes February 2004 53:463-473; doi:10.2337/diabetes.53.2.463

Genetics

Select this article
- Juliette Janson,
- Thomas Laedtke,
- Joseph E. Parisi,
- Peter O’Brien,
- Ronald C. Petersen,
- and Peter C. Butler
Increased Risk of Type 2 Diabetes in Alzheimer Disease
Diabetes February 2004 53:474-481; doi:10.2337/diabetes.53.2.474
Select this article
- Miyoshi Sasahara,
- Masahiro Nishi,
- Hiromichi Kawashima,
- Kazuya Ueda,
- Setsuya Sakagashira,
- Hiroto Furuta,
- Eisaku Matsumoto,
- Tadashi Hanabusa,
- Hideyuki Sasaki,
- and Kishio Nanjo
Uncoupling Protein 2 Promoter Polymorphism −866G/A Affects Its Expression in β-Cells and Modulates Clinical Profiles of Japanese Type 2 Diabetic Patients
Diabetes February 2004 53:482-485; doi:10.2337/diabetes.53.2.482
Select this article
- Marcus G. Pezzolesi,
- Moonsuk Nam,
- Terumasa Nagase,
- Tomasz Klupa,
- Jonathon S. Dunn,
- Wojciech M. Mlynarski,
- Stephen S. Rich,
- James H. Warram,
- and Andrzej S. Krolewski
Examination of Candidate Chromosomal Regions for Type 2 Diabetes Reveals a Susceptibility Locus on Human Chromosome 8p23.1
Diabetes February 2004 53:486-491; doi:10.2337/diabetes.53.2.486
Select this article
- Swapan Kumar Das,
- Sandra J. Hasstedt,
- Zhengxian Zhang,
- and Steven C. Elbein
Linkage and Association Mapping of a Chromosome 1q21-q24 Type 2 Diabetes Susceptibility Locus in Northern European Caucasians
Diabetes February 2004 53:492-499; doi:10.2337/diabetes.53.2.492

Brief Genetics Report

Select this article
- Lorna W. Harries,
- Andrew T. Hattersley,
- and Sian Ellard
Messenger RNA Transcripts of the Hepatocyte Nuclear Factor-1α Gene Containing Premature Termination Codons Are Subject to Nonsense-Mediated Decay
Diabetes February 2004 53:500-504; doi:10.2337/diabetes.53.2.500
Select this article
- Felicity Payne,
- Deborah J. Smyth,
- Rebecca Pask,
- Bryan J. Barratt,
- Jason D. Cooper,
- Rebecca C.J. Twells,
- Neil M. Walker,
- Alex C. Lam,
- Luc J. Smink,
- Sarah Nutland,
- Helen E. Rance,
- and John A. Todd
Haplotype Tag Single Nucleotide Polymorphism Analysis of the Human Orthologues of the Rat Type 1 Diabetes Genes Ian4 (Lyp/Iddm1) and Cblb
Diabetes February 2004 53:505-509; doi:10.2337/diabetes.53.2.505

Banting Lecture 2003

Autoimmune Diabetes and the Circle of Tolerance

Perspectives in Diabetes

Chronic Sympathetic Activation: Consequence and Cause of Age-Associated Obesity?

Metabolism

Suppression of Endogenous Glucose Production by Mild Hyperinsulinemia During Exercise Is Determined Predominantly by Portal Venous Insulin

Strength Training Increases Insulin-Mediated Glucose Uptake, GLUT4 Content, and Insulin Signaling in Skeletal Muscle in Patients With Type 2 Diabetes

Hexokinase II Overexpression Improves Exercise-Stimulated But Not Insulin-Stimulated Muscle Glucose Uptake in High-Fat-Fed C57BL/6J Mice

Effect of Moderate Exercise Training on Peripheral Glucose Effectiveness, Insulin Sensitivity, and Endogenous Glucose Production in Healthy Humans Estimated by a Two-Compartment-Labeled Minimal Model

Signal Transduction

Sterol Regulatory Element-Binding Protein-1 Mediates the Effect of Insulin on Hexokinase II Gene Expression in Human Muscle Cells

Ca2+ and AMPK Both Mediate Stimulation of Glucose Transport by Muscle Contractions

Obesity Study

Prevention of Obesity and Insulin Resistance in Mice Lacking Plasminogen Activator Inhibitor 1

Leptin Impairs Insulin Signaling in Rat Adipocytes

Immunology and Transplantation

Proinsulin Expression by Hassall’s Corpuscles in the Mouse Thymus

Exercise Induces Hypoglycemia in Rats With Islet Transplantation

Gene Expression Profiles Define a Key Checkpoint for Type 1 Diabetes in NOD Mice

Mixed Hematopoietic Chimerism Allows Cure of Autoimmune Diabetes Through Allogeneic Tolerance and Reversal of Autoimmunity

Stratification of Type 1 Diabetes Risk on the Basis of Islet Autoantibody Characteristics

Islet Studies

Role for Plasma Membrane-Related Ca2+-ATPase-1 (ATP2C1) in Pancreatic β-Cell Ca2+ Homeostasis Revealed by RNA Silencing

Regulation of ATP/ADP in Pancreatic Islets

Pathophysiology

Reduction in Glucagon Receptor Expression by an Antisense Oligonucleotide Ameliorates Diabetic Syndrome in db/db Mice

Effect of Recurrent Hypoglycemia on Spatial Cognition and Cognitive Metabolism in Normal and Diabetic Rats

Insulin Secretion in Type 1 Diabetes

Electrocardiographic Repolarization Complexity and Abnormality Predict All-Cause and Cardiovascular Mortality in Diabetes: The Strong Heart Study

Decrease in Glucose-Stimulated Insulin Secretion With Aging Is Independent of Insulin Action

Insulin Sensitivity of Muscle Capillary Recruitment In Vivo

Complication

Absence of Inducible Nitric Oxide Synthase Reduces Myocardial Damage During Ischemia Reperfusion in Streptozotocin-Induced Hyperglycemic Mice

Diabetes Increases Formation of Advanced Glycation End Products on Sarco(endo)plasmic Reticulum Ca2+-ATPase

Genetics

Increased Risk of Type 2 Diabetes in Alzheimer Disease

Uncoupling Protein 2 Promoter Polymorphism −866G/A Affects Its Expression in β-Cells and Modulates Clinical Profiles of Japanese Type 2 Diabetic Patients

Examination of Candidate Chromosomal Regions for Type 2 Diabetes Reveals a Susceptibility Locus on Human Chromosome 8p23.1

Linkage and Association Mapping of a Chromosome 1q21-q24 Type 2 Diabetes Susceptibility Locus in Northern European Caucasians

Brief Genetics Report

Messenger RNA Transcripts of the Hepatocyte Nuclear Factor-1α Gene Containing Premature Termination Codons Are Subject to Nonsense-Mediated Decay

Haplotype Tag Single Nucleotide Polymorphism Analysis of the Human Orthologues of the Rat Type 1 Diabetes Genes Ian4 (Lyp/Iddm1) and Cblb

This Issue

Current Issue

Ca²⁺ and AMPK Both Mediate Stimulation of Glucose Transport by Muscle Contractions

Role for Plasma Membrane-Related Ca²⁺-ATPase-1 (ATP2C1) in Pancreatic β-Cell Ca²⁺ Homeostasis Revealed by RNA Silencing

Diabetes Increases Formation of Advanced Glycation End Products on Sarco(endo)plasmic Reticulum Ca²⁺-ATPase