Prolonged Incubation in PUGNAc Results in Increased Protein O-Linked Glycosylation and Insulin Resistance in Rat Skeletal Muscle

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FIG. 7.
FIG. 7.

Phosphorylation status of GSK3β phosphorylation following 19 h of incubation of muscle with or without PUGNAc and with 0.6 nmol/l insulin (A) (n = 7 per group) or 12 nmol/l insulin (B) (n = 11 per group). Protein blots were probed with anti-phospho-GSK3α/β. Bands corresponding to P-GSK3β (molecular weight of 46 kDa) were quantitated by densitometry and expressed as the mean ± SE.

This Article

  1. Diabetes vol. 53 no. 4 921-930