Table of Contents

Perspectives in Diabetes

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- Leslie J. Baier and
- Robert L. Hanson
Genetic Studies of the Etiology of Type 2 Diabetes in Pima Indians: Hunting for Pieces to a Complicated Puzzle
Diabetes May 2004 53:1181-1186; doi:10.2337/diabetes.53.5.1181

Metabolism

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- Kristine B. Degn,
- Claus B. Juhl,
- Jeppe Sturis,
- Grethe Jakobsen,
- Birgitte Brock,
- Visvanathan Chandramouli,
- Joergen Rungby,
- Bernard R. Landau,
- and Ole Schmitz
One Week’s Treatment With the Long-Acting Glucagon-Like Peptide 1 Derivative Liraglutide (NN2211) Markedly Improves 24-h Glycemia and α- and β-Cell Function and Reduces Endogenous Glucose Release in Patients with Type 2 Diabetes
Diabetes May 2004 53:1187-1194; doi:10.2337/diabetes.53.5.1187
Select this article
- Karen L. Cheal,
- Fahim Abbasi,
- Cindy Lamendola,
- Tracey McLaughlin,
- Gerald M. Reaven,
- and Earl S. Ford
Relationship to Insulin Resistance of the Adult Treatment Panel III Diagnostic Criteria for Identification of the Metabolic Syndrome
Diabetes May 2004 53:1195-1200; doi:10.2337/diabetes.53.5.1195
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- Garry M. Steil,
- Chi-min Hwu,
- Robert Janowski,
- Farzam Hariri,
- Sujata Jinagouda,
- Christine Darwin,
- Sameh Tadros,
- Kerstin Rebrin,
- and Mohammed F. Saad
Evaluation of Insulin Sensitivity and β-Cell Function Indexes Obtained From Minimal Model Analysis of a Meal Tolerance Test
Diabetes May 2004 53:1201-1207; doi:10.2337/diabetes.53.5.1201

Signal Transduction

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- Sean L. McGee and
- Mark Hargreaves
Exercise and Myocyte Enhancer Factor 2 Regulation in Human Skeletal Muscle
Diabetes May 2004 53:1208-1214; doi:10.2337/diabetes.53.5.1208
Select this article
- Marek Straczkowski,
- Irina Kowalska,
- Agnieszka Nikolajuk,
- Stella Dzienis-Straczkowska,
- Ida Kinalska,
- Marcin Baranowski,
- Malgorzata Zendzian-Piotrowska,
- Zofia Brzezinska,
- and Jan Gorski
Relationship Between Insulin Sensitivity and Sphingomyelin Signaling Pathway in Human Skeletal Muscle
Diabetes May 2004 53:1215-1221; doi:10.2337/diabetes.53.5.1215
Select this article
- Yukio Sassa,
- Yasuaki Hata,
- Lloyd Paul Aiello,
- Yukio Taniguchi,
- Kimitoshi Kohno,
- and Tatsuro Ishibashi
Bifunctional Properties of Peroxisome Proliferator-Activated Receptor γ1 in KDR Gene Regulation Mediated via Interaction With Both Sp1 and Sp3
Diabetes May 2004 53:1222-1229; doi:10.2337/diabetes.53.5.1222
Select this article
- Nicole M. Sanders,
- Ambrose A. Dunn-Meynell,
- and Barry E. Levin
Third Ventricular Alloxan Reversibly Impairs Glucose Counterregulatory Responses
Diabetes May 2004 53:1230-1236; doi:10.2337/diabetes.53.5.1230

Obesity Study

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- Gregory S. Fraley,
- Jarrad M. Scarlett,
- Issei Shimada,
- Dawit N. Teklemichael,
- Blake V. Acohido,
- Donald K. Clifton,
- and Robert A. Steiner
Effects of Diabetes and Insulin on the Expression of Galanin-Like Peptide in the Hypothalamus of the Rat
Diabetes May 2004 53:1237-1242; doi:10.2337/diabetes.53.5.1237
Select this article
- Knut Tomas Dalen,
- Kristina Schoonjans,
- Stine M. Ulven,
- Mina Susanne Weedon-Fekjaer,
- Trine Gjesti Bentzen,
- Hana Koutnikova,
- Johan Auwerx,
- and Hilde I. Nebb
Adipose Tissue Expression of the Lipid Droplet–Associating Proteins S3-12 and Perilipin Is Controlled by Peroxisome Proliferator–Activated Receptor-γ
Diabetes May 2004 53:1243-1252; doi:10.2337/diabetes.53.5.1243
Select this article
- William A. Banks,
- Alan B. Coon,
- Sandra M. Robinson,
- Asif Moinuddin,
- Jessica M. Shultz,
- Ryota Nakaoke,
- and John E. Morley
Triglycerides Induce Leptin Resistance at the Blood-Brain Barrier
Diabetes May 2004 53:1253-1260; doi:10.2337/diabetes.53.5.1253
Select this article
- Alex W. Cohen,
- Babak Razani,
- William Schubert,
- Terence M. Williams,
- Xiao Bo Wang,
- Puneeth Iyengar,
- Dawn L. Brasaemle,
- Philipp E. Scherer,
- and Michael P. Lisanti
Role of Caveolin-1 in the Modulation of Lipolysis and Lipid Droplet Formation
Diabetes May 2004 53:1261-1270; doi:10.2337/diabetes.53.5.1261
Select this article
- James B. Young,
- Jeffrey Weiss,
- and Nadine Boufath
Effects of Dietary Monosaccharides on Sympathetic Nervous System Activity in Adipose Tissues of Male Rats
Diabetes May 2004 53:1271-1278; doi:10.2337/diabetes.53.5.1271
Select this article
- Barbora Vozarova de Courten,
- Mikako Degawa-Yamauchi,
- Robert V. Considine,
- and P. Antonio Tataranni
High Serum Resistin Is Associated With an Increase in Adiposity But Not a Worsening of Insulin Resistance in Pima Indians
Diabetes May 2004 53:1279-1284; doi:10.2337/diabetes.53.5.1279
Select this article
- Cyrile A. Curat,
- Alexandra Miranville,
- Coralie Sengenès,
- Michael Diehl,
- Carolin Tonus,
- Rudi Busse,
- and Anne Bouloumié
From Blood Monocytes to Adipose Tissue-Resident Macrophages: Induction of Diapedesis by Human Mature Adipocytes
Diabetes May 2004 53:1285-1292; doi:10.2337/diabetes.53.5.1285

Immunology and Transplantation

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- Emma Barinas-Mitchell,
- Susan Pietropaolo,
- Ying-Jian Zhang,
- Tyona Henderson,
- Massimo Trucco,
- Lewis H. Kuller,
- and Massimo Pietropaolo
Islet Cell Autoimmunity in a Triethnic Adult Population of the Third National Health and Nutrition Examination Survey
Diabetes May 2004 53:1293-1302; doi:10.2337/diabetes.53.5.1293
Select this article
- Qing-Sheng Mi,
- Dalam Ly,
- Peter Zucker,
- Megan McGarry,
- and Terry L. Delovitch
Interleukin-4 but not Interleukin-10 Protects Against Spontaneous and Recurrent Type 1 Diabetes by Activated CD1d-Restricted Invariant Natural Killer T-Cells
Diabetes May 2004 53:1303-1310; doi:10.2337/diabetes.53.5.1303
Select this article
- Ravi Bhargava,
- Peter A. Senior,
- Thomas E. Ackerman,
- Edmond A. Ryan,
- Breay W. Paty,
- Jonathan R.T. Lakey,
- and A.M. James Shapiro
Prevalence of Hepatic Steatosis After Islet Transplantation and Its Relation to Graft Function
Diabetes May 2004 53:1311-1317; doi:10.2337/diabetes.53.5.1311
Select this article
- Marcela Brissova,
- Michael Fowler,
- Peter Wiebe,
- Alena Shostak,
- Masakazu Shiota,
- Aramandla Radhika,
- P. Charles Lin,
- Maureen Gannon,
- and Alvin C. Powers
Intraislet Endothelial Cells Contribute to Revascularization of Transplanted Pancreatic Islets
Diabetes May 2004 53:1318-1325; doi:10.2337/diabetes.53.5.1318

Islet Study

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- Tanya Hansotia,
- Laurie L. Baggio,
- Dominique Delmeire,
- Simon A. Hinke,
- Yuichiro Yamada,
- Katsushi Tsukiyama,
- Yutaka Seino,
- Jens J. Holst,
- Frans Schuit,
- and D.J. Drucker
Double Incretin Receptor Knockout (DIRKO) Mice Reveal an Essential Role for the Enteroinsular Axis in Transducing the Glucoregulatory Actions of DPP-IV Inhibitors
Diabetes May 2004 53:1326-1335; doi:10.2337/diabetes.53.5.1326

Pathophysiology

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- Gang Ye,
- Naira S. Metreveli,
- Rajakumar V. Donthi,
- Shen Xia,
- Ming Xu,
- Edward C. Carlson,
- and Paul N. Epstein
Catalase Protects Cardiomyocyte Function in Models of Type 1 and Type 2 Diabetes
Diabetes May 2004 53:1336-1343; doi:10.2337/diabetes.53.5.1336

Complication

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- Giulio Ceolotto,
- Michela Bevilacqua,
- Italia Papparella,
- Elisabetta Baritono,
- Lorenzo Franco,
- Carlo Corvaja,
- Martina Mazzoni,
- Andrea Semplicini,
- and Angelo Avogaro
Insulin Generates Free Radicals by an NAD(P)H, Phosphatidylinositol 3′-Kinase-Dependent Mechanism in Human Skin Fibroblasts Ex Vivo
Diabetes May 2004 53:1344-1351; doi:10.2337/diabetes.53.5.1344
Select this article
- Benedek Erdös,
- James A. Snipes,
- Allison W. Miller,
- and David W. Busija
Cerebrovascular Dysfunction in Zucker Obese Rats Is Mediated by Oxidative Stress and Protein Kinase C
Diabetes May 2004 53:1352-1359; doi:10.2337/diabetes.53.5.1352

Genetics

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- Jose C. Florez,
- Noël Burtt,
- Paul I.W. de Bakker,
- Peter Almgren,
- Tiinamaija Tuomi,
- Johan Holmkvist,
- Daniel Gaudet,
- Thomas J. Hudson,
- Steve F. Schaffner,
- Mark J. Daly,
- Joel N. Hirschhorn,
- Leif Groop,
- and David Altshuler
Haplotype Structure and Genotype-Phenotype Correlations of the Sulfonylurea Receptor and the Islet ATP-Sensitive Potassium Channel Gene Region
Diabetes May 2004 53:1360-1368; doi:10.2337/diabetes.53.5.1360
Select this article
- Guowen Cai,
- Shelley A. Cole,
- Jeanne H. Freeland-Graves,
- Jean W. MacCluer,
- John Blangero,
- and Anthony G. Comuzzie
Genome-Wide Scans Reveal Quantitative Trait Loci on 8p and 13q Related to Insulin Action and Glucose Metabolism: The San Antonio Family Heart Study
Diabetes May 2004 53:1369-1374; doi:10.2337/diabetes.53.5.1369
Select this article
- Sung-Hoon Kim,
- Xiaowei Ma,
- Stanislawa Weremowicz,
- Tonino Ercolino,
- Christine Powers,
- Wojciech Mlynarski,
- K. Aviva Bashan,
- James H. Warram,
- Josyf Mychaleckyj,
- Stephen S. Rich,
- Andrzej S. Krolewski,
- and Alessandro Doria
Identification of a Locus for Maturity-Onset Diabetes of the Young on Chromosome 8p23
Diabetes May 2004 53:1375-1384; doi:10.2337/diabetes.53.5.1375
Select this article
- Hannes Oberkofler,
- Veronika Linnemayr,
- Raimund Weitgasser,
- Kerstin Klein,
- Mingqiang Xie,
- Bernhard Iglseder,
- Franz Krempler,
- Bernhard Paulweber,
- and Wolfgang Patsch
Complex Haplotypes of the PGC-1α Gene Are Associated With Carbohydrate Metabolism and Type 2 Diabetes
Diabetes May 2004 53:1385-1393; doi:10.2337/diabetes.53.5.1385

Brief Genetics Report

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- Ronan Roussel,
- David-Alexandre Trégouët,
- Samy Hadjadj,
- Xavier Jeunemaı̂tre,
- and Michel Marre
Investigation of the Human ANP Gene in Type 1 Diabetic Nephropathy: Case-Control and Follow-up Studies
Diabetes May 2004 53:1394-1398; doi:10.2337/diabetes.53.5.1394
Select this article
- Caroline S. Fox,
- Nancy L. Heard-Costa,
- Peter W.F. Wilson,
- Daniel Levy,
- Ralph B. D’Agostino, Sr.,
- and Larry D. Atwood
Genome-Wide Linkage to Chromosome 6 for Waist Circumference in the Framingham Heart Study
Diabetes May 2004 53:1399-1402; doi:10.2337/diabetes.53.5.1399

Letter to the Editor

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- Mayer B. Davidson
Status of Research Funding by the American Diabetes Association—5th and Final Year
Diabetes May 2004 53:1403; doi:10.2337/diabetes.53.5.1403

Erratum

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Erratum
Diabetes May 2004 53:1404; doi:10.2337/diabetes.53.5.1404

Diabetes

Perspectives in Diabetes

Genetic Studies of the Etiology of Type 2 Diabetes in Pima Indians: Hunting for Pieces to a Complicated Puzzle

Metabolism

One Week’s Treatment With the Long-Acting Glucagon-Like Peptide 1 Derivative Liraglutide (NN2211) Markedly Improves 24-h Glycemia and α- and β-Cell Function and Reduces Endogenous Glucose Release in Patients with Type 2 Diabetes

Relationship to Insulin Resistance of the Adult Treatment Panel III Diagnostic Criteria for Identification of the Metabolic Syndrome

Evaluation of Insulin Sensitivity and β-Cell Function Indexes Obtained From Minimal Model Analysis of a Meal Tolerance Test

Signal Transduction

Exercise and Myocyte Enhancer Factor 2 Regulation in Human Skeletal Muscle

Relationship Between Insulin Sensitivity and Sphingomyelin Signaling Pathway in Human Skeletal Muscle

Bifunctional Properties of Peroxisome Proliferator-Activated Receptor γ1 in KDR Gene Regulation Mediated via Interaction With Both Sp1 and Sp3

Third Ventricular Alloxan Reversibly Impairs Glucose Counterregulatory Responses

Obesity Study

Effects of Diabetes and Insulin on the Expression of Galanin-Like Peptide in the Hypothalamus of the Rat

Adipose Tissue Expression of the Lipid Droplet–Associating Proteins S3-12 and Perilipin Is Controlled by Peroxisome Proliferator–Activated Receptor-γ

Triglycerides Induce Leptin Resistance at the Blood-Brain Barrier

Role of Caveolin-1 in the Modulation of Lipolysis and Lipid Droplet Formation

Effects of Dietary Monosaccharides on Sympathetic Nervous System Activity in Adipose Tissues of Male Rats

High Serum Resistin Is Associated With an Increase in Adiposity But Not a Worsening of Insulin Resistance in Pima Indians

From Blood Monocytes to Adipose Tissue-Resident Macrophages: Induction of Diapedesis by Human Mature Adipocytes

Immunology and Transplantation

Islet Cell Autoimmunity in a Triethnic Adult Population of the Third National Health and Nutrition Examination Survey

Interleukin-4 but not Interleukin-10 Protects Against Spontaneous and Recurrent Type 1 Diabetes by Activated CD1d-Restricted Invariant Natural Killer T-Cells

Prevalence of Hepatic Steatosis After Islet Transplantation and Its Relation to Graft Function

Intraislet Endothelial Cells Contribute to Revascularization of Transplanted Pancreatic Islets

Islet Study

Double Incretin Receptor Knockout (DIRKO) Mice Reveal an Essential Role for the Enteroinsular Axis in Transducing the Glucoregulatory Actions of DPP-IV Inhibitors

Pathophysiology

Catalase Protects Cardiomyocyte Function in Models of Type 1 and Type 2 Diabetes

Complication

Insulin Generates Free Radicals by an NAD(P)H, Phosphatidylinositol 3′-Kinase-Dependent Mechanism in Human Skin Fibroblasts Ex Vivo

Cerebrovascular Dysfunction in Zucker Obese Rats Is Mediated by Oxidative Stress and Protein Kinase C

Genetics

Haplotype Structure and Genotype-Phenotype Correlations of the Sulfonylurea Receptor and the Islet ATP-Sensitive Potassium Channel Gene Region

Genome-Wide Scans Reveal Quantitative Trait Loci on 8p and 13q Related to Insulin Action and Glucose Metabolism: The San Antonio Family Heart Study

Identification of a Locus for Maturity-Onset Diabetes of the Young on Chromosome 8p23

Complex Haplotypes of the PGC-1α Gene Are Associated With Carbohydrate Metabolism and Type 2 Diabetes

Brief Genetics Report

Investigation of the Human ANP Gene in Type 1 Diabetic Nephropathy: Case-Control and Follow-up Studies

Genome-Wide Linkage to Chromosome 6 for Waist Circumference in the Framingham Heart Study

Letter to the Editor

Status of Research Funding by the American Diabetes Association—5th and Final Year

Erratum

Erratum

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