Table of Contents

Perspectives in Diabetes

Select this article
- Domenico Accili
Lilly Lecture 2003: The Struggle for Mastery in Insulin Action: From Triumvirate to Republic
Diabetes July 2004 53:1633-1642; doi:10.2337/diabetes.53.7.1633

Metabolism

Select this article
- Mark A. Febbraio,
- Natalie Hiscock,
- Massimo Sacchetti,
- Christian P. Fischer,
- and Bente K. Pedersen
Interleukin-6 Is a Novel Factor Mediating Glucose Homeostasis During Skeletal Muscle Contraction
Diabetes July 2004 53:1643-1648; doi:10.2337/diabetes.53.7.1643
Select this article
- Miguel A. Iglesias,
- Stuart M. Furler,
- Gregory J. Cooney,
- Edward W. Kraegen,
- and Ji-Ming Ye
AMP-Activated Protein Kinase Activation by AICAR Increases Both Muscle Fatty Acid and Glucose Uptake in White Muscle of Insulin-Resistant Rats In Vivo
Diabetes July 2004 53:1649-1654; doi:10.2337/diabetes.53.7.1649
Select this article
- Susan L.M. Coort,
- Danny M. Hasselbaink,
- Debby P.Y. Koonen,
- Jodil Willems,
- Will A. Coumans,
- Adrian Chabowski,
- Ger J. van der Vusse,
- Arend Bonen,
- Jan F.C. Glatz,
- and Joost J.F.P. Luiken
Enhanced Sarcolemmal FAT/CD36 Content and Triacylglycerol Storage in Cardiac Myocytes From Obese Zucker Rats
Diabetes July 2004 53:1655-1663; doi:10.2337/diabetes.53.7.1655

Signal Transduction

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- Daniel Walcher,
- Milos Aleksic,
- Verena Jerg,
- Vinzenz Hombach,
- Arthur Zieske,
- Satoki Homma,
- Jack Strong,
- and Nikolaus Marx
C-Peptide Induces Chemotaxis of Human CD4-Positive Cells: Involvement of Pertussis Toxin–Sensitive G-Proteins and Phosphoinositide 3-Kinase
Diabetes July 2004 53:1664-1670; doi:10.2337/diabetes.53.7.1664

Obesity Study

Select this article
- Michael W. Rajala,
- Yong Qi,
- Hiral R. Patel,
- Nobuhiko Takahashi,
- Ronadip Banerjee,
- Utpal B. Pajvani,
- Madhur K. Sinha,
- Ronald L. Gingerich,
- Philipp E. Scherer,
- and Rexford S. Ahima
Regulation of Resistin Expression and Circulating Levels in Obesity, Diabetes, and Fasting
Diabetes July 2004 53:1671-1679; doi:10.2337/diabetes.53.7.1671

Immunology and Transplantation

Select this article
- Renata Auricchio,
- Francesco Paparo,
- Maria Maglio,
- Adriana Franzese,
- Francesca Lombardi,
- Giuliana Valerio,
- Gerardo Nardone,
- Selvaggia Percopo,
- Luigi Greco,
- and Riccardo Troncone
In Vitro–Deranged Intestinal Immune Response to Gliadin in Type 1 Diabetes
Diabetes July 2004 53:1680-1683; doi:10.2337/diabetes.53.7.1680
Select this article
- Atsutaka Kubosaki,
- Steffen Gross,
- Junnosuke Miura,
- Keiichi Saeki,
- Min Zhu,
- Shinichiro Nakamura,
- Wiljan Hendriks,
- and Abner Louis Notkins
Targeted Disruption of the IA-2β Gene Causes Glucose Intolerance and Impairs Insulin Secretion but Does Not Prevent the Development of Diabetes in NOD Mice
Diabetes July 2004 53:1684-1691; doi:10.2337/diabetes.53.7.1684
Select this article
- Timothy I.M. Tree,
- Gaby Duinkerken,
- Sabine Willemen,
- René R.P. de Vries,
- and Bart O. Roep
HLA-DQ–Regulated T-Cell Responses to Islet Cell Autoantigens Insulin and GAD65
Diabetes July 2004 53:1692-1699; doi:10.2337/diabetes.53.7.1692
Select this article
- Norihiko Ogawa,
- James F. List,
- Joel F. Habener,
- and Takashi Maki
Cure of Overt Diabetes in NOD Mice by Transient Treatment With Anti-Lymphocyte Serum and Exendin-4
Diabetes July 2004 53:1700-1705; doi:10.2337/diabetes.53.7.1700

Islet Study

Select this article
- Kathrin Maedler,
- Joachim Størling,
- Jeppe Sturis,
- Richard A. Zuellig,
- Giatgen A. Spinas,
- Per O.G. Arkhammar,
- Thomas Mandrup-Poulsen,
- and Marc Y. Donath
Glucose- and Interleukin-1β-Induced β-Cell Apoptosis Requires Ca²⁺ Influx and Extracellular Signal-Regulated Kinase (ERK) 1/2 Activation and Is Prevented by a Sulfonylurea Receptor 1/Inwardly Rectifying K⁺ Channel 6.2 (SUR/Kir6.2) Selective Potassium Channel Opener in Human Islets
Diabetes July 2004 53:1706-1713; doi:10.2337/diabetes.53.7.1706
Select this article
- Alokesh Duttaroy,
- Charles L. Zimliki,
- Dinesh Gautam,
- Yinghong Cui,
- David Mears,
- and Jürgen Wess
Muscarinic Stimulation of Pancreatic Insulin and Glucagon Release Is Abolished in M₃ Muscarinic Acetylcholine Receptor–Deficient Mice
Diabetes July 2004 53:1714-1720; doi:10.2337/diabetes.53.7.1714
Select this article
- Dong-Qi Tang,
- Li-Zhen Cao,
- Brant R. Burkhardt,
- Chang-Qi Xia,
- Sally A. Litherland,
- Mark A. Atkinson,
- and Li-Jun Yang
In Vivo and In Vitro Characterization of Insulin-Producing Cells Obtained From Murine Bone Marrow
Diabetes July 2004 53:1721-1732; doi:10.2337/diabetes.53.7.1721
Select this article
- Marie-Line Peyot,
- Christopher J. Nolan,
- Krishnakant Soni,
- Erik Joly,
- Roxane Lussier,
- Barbara E. Corkey,
- Shu Pei Wang,
- Grant A. Mitchell,
- and Marc Prentki
Hormone-Sensitive Lipase Has a Role in Lipid Signaling for Insulin Secretion but Is Nonessential for the Incretin Action of Glucagon-Like Peptide 1
Diabetes July 2004 53:1733-1742; doi:10.2337/diabetes.53.7.1733
Select this article
- Akiko Muroyama,
- Shunsuke Uehara,
- Shouki Yatsushiro,
- Noriko Echigo,
- Riyo Morimoto,
- Mitsuhiro Morita,
- Mitsuko Hayashi,
- Akitsugu Yamamoto,
- Duk-Su Koh,
- and Yoshinori Moriyama
A Novel Variant of Ionotropic Glutamate Receptor Regulates Somatostatin Secretion From δ-Cells of Islets of Langerhans
Diabetes July 2004 53:1743-1753; doi:10.2337/diabetes.53.7.1743
Select this article
- Claudia Frigeri,
- Cyrus C. Martin,
- Christina A. Svitek,
- James K. Oeser,
- John C. Hutton,
- Maureen Gannon,
- and Richard M. O’Brien
The Proximal Islet-Specific Glucose-6-Phosphatase Catalytic Subunit–Related Protein Autoantigen Promoter Is Sufficient to Initiate but not Maintain Transgene Expression in Mouse Islets in Vivo
Diabetes July 2004 53:1754-1764; doi:10.2337/diabetes.53.7.1754
Select this article
- Craig S. Nunemaker,
- Min Zhang,
- and Leslie S. Satin
Insulin Feedback Alters Mitochondrial Activity Through an ATP-sensitive K⁺ Channel–Dependent Pathway in Mouse Islets and β-Cells
Diabetes July 2004 53:1765-1772; doi:10.2337/diabetes.53.7.1765

Pathophysiology

Select this article
- Anthony J.G. Hanley,
- Andreas Festa,
- Ralph B. D’Agostino, Jr.,
- Lynne E. Wagenknecht,
- Peter J. Savage,
- Russell P. Tracy,
- Mohammed F. Saad,
- and Steven M. Haffner
Metabolic and Inflammation Variable Clusters and Prediction of Type 2 Diabetes: Factor Analysis Using Directly Measured Insulin Sensitivity
Diabetes July 2004 53:1773-1781; doi:10.2337/diabetes.53.7.1773
Select this article
- Enzo Bonora,
- Stefan Kiechl,
- Johann Willeit,
- Friedrich Oberhollenzer,
- Georg Egger,
- James B. Meigs,
- Riccardo C. Bonadonna,
- and Michele Muggeo
Population-Based Incidence Rates and Risk Factors for Type 2 Diabetes in White Individuals: The Bruneck Study
Diabetes July 2004 53:1782-1789; doi:10.2337/diabetes.53.7.1782
Select this article
- Dake Qi,
- Thomas Pulinilkunnil,
- Ding An,
- Sanjoy Ghosh,
- Ashraf Abrahani,
- John Andrew Pospisilik,
- Roger Brownsey,
- Rich Wambolt,
- Michael Allard,
- and Brian Rodrigues
Single-Dose Dexamethasone Induces Whole-Body Insulin Resistance and Alters Both Cardiac Fatty Acid and Carbohydrate Metabolism
Diabetes July 2004 53:1790-1797; doi:10.2337/diabetes.53.7.1790
Select this article
- Darleen A. Sandoval,
- Deanna L. Aftab Guy,
- M. Antoinette Richardson,
- Andrew C. Ertl,
- and Stephen N. Davis
Effects of Low and Moderate Antecedent Exercise on Counterregulatory Responses to Subsequent Hypoglycemia in Type 1 Diabetes
Diabetes July 2004 53:1798-1806; doi:10.2337/diabetes.53.7.1798

Complications

Select this article
- Andrew P. Mizisin,
- Yvonne Vu,
- Michelle Shuff,
- and Nigel A. Calcutt
Ciliary Neurotrophic Factor Improves Nerve Conduction and Ameliorates Regeneration Deficits in Diabetic Rats
Diabetes July 2004 53:1807-1812; doi:10.2337/diabetes.53.7.1807
Select this article
- Josephine M. Forbes,
- Louis Teo Loon Yee,
- Vicki Thallas,
- Markus Lassila,
- Riccardo Candido,
- Karin A. Jandeleit-Dahm,
- Merlin C. Thomas,
- Wendy C. Burns,
- Elizabeth K. Deemer,
- Susan R. Thorpe,
- Mark E. Cooper,
- and Terri J. Allen
Advanced Glycation End Product Interventions Reduce Diabetes-Accelerated Atherosclerosis
Diabetes July 2004 53:1813-1823; doi:10.2337/diabetes.53.7.1813
Select this article
- Valentine Brussee,
- F. Alexander Cunningham,
- and Douglas W. Zochodne
Direct Insulin Signaling of Neurons Reverses Diabetic Neuropathy
Diabetes July 2004 53:1824-1830; doi:10.2337/diabetes.53.7.1824
Select this article
- Yoshihiko Yamamoto,
- Yohei Maeshima,
- Hiroyuki Kitayama,
- Shinji Kitamura,
- Yuki Takazawa,
- Hitoshi Sugiyama,
- Yasushi Yamasaki,
- and Hirofumi Makino
Tumstatin Peptide, an Inhibitor of Angiogenesis, Prevents Glomerular Hypertrophy in the Early Stage of Diabetic Nephropathy
Diabetes July 2004 53:1831-1840; doi:10.2337/diabetes.53.7.1831
Select this article
- Daigo Sumi and
- Louis J. Ignarro
Regulation of Inducible Nitric Oxide Synthase Expression in Advanced Glycation End Product–Stimulated RAW 264.7 Cells: The Role of Heme Oxygenase-1 and Endogenous Nitric Oxide
Diabetes July 2004 53:1841-1850; doi:10.2337/diabetes.53.7.1841
Select this article
- Sally A. Price,
- Sithiporn Agthong,
- Alicia B. Middlemas,
- and David R. Tomlinson
Mitogen-Activated Protein Kinase p38 Mediates Reduced Nerve Conduction Velocity in Experimental Diabetic Neuropathy: Interactions With Aldose Reductase
Diabetes July 2004 53:1851-1856; doi:10.2337/diabetes.53.7.1851

Genetics

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- Christopher G. Bell,
- Michael Benzinou,
- Afshan Siddiq,
- Cécile Lecoeur,
- Christian Dina,
- Arnaud Lemainque,
- Karine Clément,
- Arnaud Basdevant,
- Bernard Guy-Grand,
- Charles A. Mein,
- David Meyre,
- and Philippe Froguel
Genome-wide Linkage Analysis for Severe Obesity in French Caucasians Finds Significant Susceptibility Locus on Chromosome 19q
Diabetes July 2004 53:1857-1865; doi:10.2337/diabetes.53.7.1857
Select this article
- Stephen S. Rich,
- Donald W. Bowden,
- Steven M. Haffner,
- Jill M. Norris,
- Mohammed F. Saad,
- Braxton D. Mitchell,
- Jerome I. Rotter,
- Carl D. Langefeld,
- Lynne E. Wagenknecht,
- and Richard N. Bergman
Identification of Quantitative Trait Loci for Glucose Homeostasis: The Insulin Resistance Atherosclerosis Study (IRAS) Family Study
Diabetes July 2004 53:1866-1875; doi:10.2337/diabetes.53.7.1866

Brief Genetics Report

Select this article
- Valérie Senée,
- Krishna M. Vattem,
- Marc Delépine,
- Lynn A. Rainbow,
- Céline Haton,
- Annick Lecoq,
- Nick J. Shaw,
- Jean-Jacques Robert,
- Raoul Rooman,
- Catherine Diatloff-Zito,
- Jacques L. Michaud,
- Bassan Bin-Abbas,
- Doris Taha,
- Bernard Zabel,
- Piergiorgio Franceschini,
- A. Kemal Topaloglu,
- G. Mark Lathrop,
- Timothy G. Barrett,
- Marc Nicolino,
- Ronald C. Wek,
- and Cécile Julier
Wolcott-Rallison Syndrome: Clinical, Genetic, and Functional Study of EIF2AK3 Mutations and Suggestion of Genetic Heterogeneity
Diabetes July 2004 53:1876-1883; doi:10.2337/diabetes.53.7.1876
Select this article
- Bryan J. Barratt,
- Felicity Payne,
- Chris E. Lowe,
- Robert Hermann,
- Barry C. Healy,
- Denise Harold,
- Patrick Concannon,
- Neda Gharani,
- Mark I. McCarthy,
- Mark G. Olavesen,
- Rose McCormack,
- Cristian Guja,
- Constantin Ionescu-Tîrgovişte,
- Dag E. Undlien,
- Kjersti S. Rønningen,
- Kathleen M. Gillespie,
- Eva Tuomilehto-Wolf,
- Jaakko Tuomilehto,
- Simon T. Bennett,
- David G. Clayton,
- Heather J. Cordell,
- and John A. Todd
Remapping the Insulin Gene/IDDM2 Locus in Type 1 Diabetes
Diabetes July 2004 53:1884-1889; doi:10.2337/diabetes.53.7.1884
Select this article
- David Owerbach,
- Lazaro Piña,
- and Kenneth H. Gabbay
A 212-kb Region on Chromosome 6q25 Containing the TAB2 Gene Is Associated With Susceptibility to Type 1 Diabetes
Diabetes July 2004 53:1890-1893; doi:10.2337/diabetes.53.7.1890
Select this article
- Camilla Cervin,
- Brita Liljeström,
- Tiinamaija Tuomi,
- Seija Heikkinen,
- Juha S. Tapanainen,
- Leif Groop,
- and Corrado M. Cilio
Cosegregation of MIDD and MODY in a Pedigree: Functional and Clinical Consequences
Diabetes July 2004 53:1894-1899; doi:10.2337/diabetes.53.7.1894
Select this article
- Pamela J. Kaisaki,
- Marc Delépine,
- Peng Y. Woon,
- Liam Sebag-Montefiore,
- Steven P. Wilder,
- Stephan Menzel,
- Nathalie Vionnet,
- Evelyne Marion,
- Jean-Pierre Riveline,
- Guillaume Charpentier,
- Stéphane Schurmans,
- Jonathan C. Levy,
- Mark Lathrop,
- Martin Farrall,
- and Dominique Gauguier
Polymorphisms in Type II SH2 Domain–Containing Inositol 5-Phosphatase (INPPL1, SHIP2) Are Associated With Physiological Abnormalities of the Metabolic Syndrome
Diabetes July 2004 53:1900-1904; doi:10.2337/diabetes.53.7.1900
Select this article
- Monica D’Adamo,
- Lucia Perego,
- Marina Cardellini,
- Maria Adelaide Marini,
- Simona Frontoni,
- Francesco Andreozzi,
- Angela Sciacqua,
- Davide Lauro,
- Paolo Sbraccia,
- Massimo Federici,
- Michele Paganelli,
- Antonio E. Pontiroli,
- Renato Lauro,
- Francesco Perticone,
- Franco Folli,
- and Giorgio Sesti
The −866A/A Genotype in the Promoter of the Human Uncoupling Protein 2 Gene Is Associated With Insulin Resistance and Increased Risk of Type 2 Diabetes
Diabetes July 2004 53:1905-1910; doi:10.2337/diabetes.53.7.1905
Select this article
- Patrizia Zavattari,
- Elisabetta Deidda,
- Maristella Pitzalis,
- Barbara Zoa,
- Loredana Moi,
- Rosanna Lampis,
- Daniela Contu,
- Costantino Motzo,
- Paola Frongia,
- Efisio Angius,
- Mario Maioli,
- John A. Todd,
- and Francesco Cucca
No Association Between Variation of the FOXP3 Gene and Common Type 1 Diabetes in the Sardinian Population
Diabetes July 2004 53:1911-1914; doi:10.2337/diabetes.53.7.1911
Select this article
- Peter Kovacs,
- Inge Harper,
- Robert L. Hanson,
- Aniello M. Infante,
- Clifton Bogardus,
- P. Antonio Tataranni,
- and Leslie J. Baier
A Novel Missense Substitution (Val1483Ile) in the Fatty Acid Synthase Gene (FAS) Is Associated With Percentage of Body Fat and Substrate Oxidation Rates in Nondiabetic Pima Indians
Diabetes July 2004 53:1915-1919; doi:10.2337/diabetes.53.7.1915

Pharmacology and Therapeutics

Select this article
- Corinna Schoelch,
- Johanna Kuhlmann,
- Matthias Gossel,
- Guenter Mueller,
- Claudia Neumann-Haefelin,
- Ulrich Belz,
- Juergen Kalisch,
- Gabriele Biemer-Daub,
- Werner Kramer,
- Hans-Paul Juretschke,
- and Andreas W. Herling
Characterization of Adenosine-A1 Receptor–Mediated Antilipolysis in Rats by Tissue Microdialysis, ¹H-Spectroscopy, and Glucose Clamp Studies
Diabetes July 2004 53:1920-1926; doi:10.2337/diabetes.53.7.1920
Select this article
- Laura Raimondi,
- Petra De Paoli,
- Edoardo Mannucci,
- Giuseppe Lonardo,
- Laura Sartiani,
- Grazia Banchelli,
- Renato Pirisino,
- Alessandro Mugelli,
- and Elisabetta Cerbai
Restoration of Cardiomyocyte Functional Properties by Angiotensin II Receptor Blockade in Diabetic Rats
Diabetes July 2004 53:1927-1933; doi:10.2337/diabetes.53.7.1927

Erratum

Select this article

Erratum
Diabetes July 2004 53:1934; doi:10.2337/diabetes.53.7.1934

Diabetes

Perspectives in Diabetes

Lilly Lecture 2003: The Struggle for Mastery in Insulin Action: From Triumvirate to Republic

Metabolism

Interleukin-6 Is a Novel Factor Mediating Glucose Homeostasis During Skeletal Muscle Contraction

AMP-Activated Protein Kinase Activation by AICAR Increases Both Muscle Fatty Acid and Glucose Uptake in White Muscle of Insulin-Resistant Rats In Vivo

Enhanced Sarcolemmal FAT/CD36 Content and Triacylglycerol Storage in Cardiac Myocytes From Obese Zucker Rats

Signal Transduction

C-Peptide Induces Chemotaxis of Human CD4-Positive Cells: Involvement of Pertussis Toxin–Sensitive G-Proteins and Phosphoinositide 3-Kinase

Obesity Study

Regulation of Resistin Expression and Circulating Levels in Obesity, Diabetes, and Fasting

Immunology and Transplantation

In Vitro–Deranged Intestinal Immune Response to Gliadin in Type 1 Diabetes

Targeted Disruption of the IA-2β Gene Causes Glucose Intolerance and Impairs Insulin Secretion but Does Not Prevent the Development of Diabetes in NOD Mice

HLA-DQ–Regulated T-Cell Responses to Islet Cell Autoantigens Insulin and GAD65

Cure of Overt Diabetes in NOD Mice by Transient Treatment With Anti-Lymphocyte Serum and Exendin-4

Islet Study

Glucose- and Interleukin-1β-Induced β-Cell Apoptosis Requires Ca2+ Influx and Extracellular Signal-Regulated Kinase (ERK) 1/2 Activation and Is Prevented by a Sulfonylurea Receptor 1/Inwardly Rectifying K+ Channel 6.2 (SUR/Kir6.2) Selective Potassium Channel Opener in Human Islets

Muscarinic Stimulation of Pancreatic Insulin and Glucagon Release Is Abolished in M3 Muscarinic Acetylcholine Receptor–Deficient Mice

In Vivo and In Vitro Characterization of Insulin-Producing Cells Obtained From Murine Bone Marrow

Hormone-Sensitive Lipase Has a Role in Lipid Signaling for Insulin Secretion but Is Nonessential for the Incretin Action of Glucagon-Like Peptide 1

A Novel Variant of Ionotropic Glutamate Receptor Regulates Somatostatin Secretion From δ-Cells of Islets of Langerhans

The Proximal Islet-Specific Glucose-6-Phosphatase Catalytic Subunit–Related Protein Autoantigen Promoter Is Sufficient to Initiate but not Maintain Transgene Expression in Mouse Islets in Vivo

Insulin Feedback Alters Mitochondrial Activity Through an ATP-sensitive K+ Channel–Dependent Pathway in Mouse Islets and β-Cells

Pathophysiology

Metabolic and Inflammation Variable Clusters and Prediction of Type 2 Diabetes: Factor Analysis Using Directly Measured Insulin Sensitivity

Population-Based Incidence Rates and Risk Factors for Type 2 Diabetes in White Individuals: The Bruneck Study

Single-Dose Dexamethasone Induces Whole-Body Insulin Resistance and Alters Both Cardiac Fatty Acid and Carbohydrate Metabolism

Effects of Low and Moderate Antecedent Exercise on Counterregulatory Responses to Subsequent Hypoglycemia in Type 1 Diabetes

Complications

Ciliary Neurotrophic Factor Improves Nerve Conduction and Ameliorates Regeneration Deficits in Diabetic Rats

Advanced Glycation End Product Interventions Reduce Diabetes-Accelerated Atherosclerosis

Direct Insulin Signaling of Neurons Reverses Diabetic Neuropathy

Tumstatin Peptide, an Inhibitor of Angiogenesis, Prevents Glomerular Hypertrophy in the Early Stage of Diabetic Nephropathy

Regulation of Inducible Nitric Oxide Synthase Expression in Advanced Glycation End Product–Stimulated RAW 264.7 Cells: The Role of Heme Oxygenase-1 and Endogenous Nitric Oxide

Mitogen-Activated Protein Kinase p38 Mediates Reduced Nerve Conduction Velocity in Experimental Diabetic Neuropathy: Interactions With Aldose Reductase

Genetics

Genome-wide Linkage Analysis for Severe Obesity in French Caucasians Finds Significant Susceptibility Locus on Chromosome 19q

Identification of Quantitative Trait Loci for Glucose Homeostasis: The Insulin Resistance Atherosclerosis Study (IRAS) Family Study

Brief Genetics Report

Wolcott-Rallison Syndrome: Clinical, Genetic, and Functional Study of EIF2AK3 Mutations and Suggestion of Genetic Heterogeneity

Remapping the Insulin Gene/IDDM2 Locus in Type 1 Diabetes

A 212-kb Region on Chromosome 6q25 Containing the TAB2 Gene Is Associated With Susceptibility to Type 1 Diabetes

Cosegregation of MIDD and MODY in a Pedigree: Functional and Clinical Consequences

Polymorphisms in Type II SH2 Domain–Containing Inositol 5-Phosphatase (INPPL1, SHIP2) Are Associated With Physiological Abnormalities of the Metabolic Syndrome

The −866A/A Genotype in the Promoter of the Human Uncoupling Protein 2 Gene Is Associated With Insulin Resistance and Increased Risk of Type 2 Diabetes

No Association Between Variation of the FOXP3 Gene and Common Type 1 Diabetes in the Sardinian Population

A Novel Missense Substitution (Val1483Ile) in the Fatty Acid Synthase Gene (FAS) Is Associated With Percentage of Body Fat and Substrate Oxidation Rates in Nondiabetic Pima Indians

Pharmacology and Therapeutics

Characterization of Adenosine-A1 Receptor–Mediated Antilipolysis in Rats by Tissue Microdialysis, 1H-Spectroscopy, and Glucose Clamp Studies

Restoration of Cardiomyocyte Functional Properties by Angiotensin II Receptor Blockade in Diabetic Rats

Erratum

Erratum

This Issue

Current Issue

Glucose- and Interleukin-1β-Induced β-Cell Apoptosis Requires Ca²⁺ Influx and Extracellular Signal-Regulated Kinase (ERK) 1/2 Activation and Is Prevented by a Sulfonylurea Receptor 1/Inwardly Rectifying K⁺ Channel 6.2 (SUR/Kir6.2) Selective Potassium Channel Opener in Human Islets

Muscarinic Stimulation of Pancreatic Insulin and Glucagon Release Is Abolished in M₃ Muscarinic Acetylcholine Receptor–Deficient Mice

Insulin Feedback Alters Mitochondrial Activity Through an ATP-sensitive K⁺ Channel–Dependent Pathway in Mouse Islets and β-Cells

Characterization of Adenosine-A1 Receptor–Mediated Antilipolysis in Rats by Tissue Microdialysis, ¹H-Spectroscopy, and Glucose Clamp Studies