Five Stages of Evolving Beta-Cell Dysfunction During Progression to Diabetes
(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.
Four weeks after transplantation of 750 syngeneic islets contained in an immunobarrier device into streptozocin diabetic B6AF1
mice, the recipients fall into two discrete groups: those with near-normal blood glucose levels and those with severe diabetes.
Figure based on data of Suzuki et al. (38).