Five Stages of Evolving Beta-Cell Dysfunction During Progression to Diabetes

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

FIG. 3.
FIG. 3.

Four- to six-week-old rats were subjected to near identical 90% partial pancreatectomies. Although glucose levels were scattered during the early stages, by 10 weeks two distinct groups emerged, one with near-normal blood glucose levels and one with unequivocal diabetes. Figure based on data of Laybutt et al. (32).

This Article

  1. Diabetes vol. 53 no. suppl 3 S16-S21