Deficiency of Subsarcolemmal Mitochondria in Obesity and Type 2 Diabetes

TABLE 2

Clinical characteristics of research volunteers

Lean Obese Type 2 diabetes
n (F/M) 4/4 3/9 2/9
Age (years) 43.2 ± 2.1* 50.5 ± 3.4 52.6 ± 2.2
Weight (kg) 66.3 ± 5.4* 90.9 ± 4.1 95.2 ± 4.8
BMI (kg/m2) 22.5 ± 0.9* 30.3 ± 1.1 29.4 ± 1.1
Fasting glucose (mg/dl) 82.0 ± 1.2* 89.2 ± 2.0* 163.8 ± 13.4
HbA1c (%) 5.0 ± 0.1* 5.0 ± 0.1* 8.0 ± 0.4
Fasting insulin (μU/ml) 5.0 ± 0.3* 11.1 ± 0.7 11.4 ± 1.5
Rd (mg · min−1 · kg FFM−1) 12.2 ± 0.7* 6.4 ± 0.4 4.9 ± 0.8
  • *

    * P < 0.05, lean or obese vs. type 2 diabetes. FFM, fat-free mass.

This Article

  1. Diabetes vol. 54 no. 1 8-14