Deficiency of Subsarcolemmal Mitochondria in Obesity and Type 2 Diabetes

TABLE 4

Mitochondrial DNA content in skeletal muscle in lean, obese, and type 2 diabetic research volunteers

Lean Obese Type 2 diabetes
n 6 12 5
mtDNA 2,514 ± 505 1,665 ± 213* 1,850 ± 220*
Succinate oxidase (units/mU CK) 0.39 ± 0.07 0.14 ± 0.02* 0.11 ± 0.01*
  • *

    * P < 0.05 vs. values in lean.

This Article

  1. Diabetes vol. 54 no. 1 8-14