Glucose Transporters in Human Renal Proximal Tubular Cells Isolated From the Urine of Patients With Non–Insulin-Dependent Diabetes

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FIG. 6.
FIG. 6.

Immunoblot representing SGLT2 and GLUT2 protein expression in HEPTECs isolated from healthy (H) and type 2 diabetic (D) volunteers’ fresh urine (n = 4). The predicted band of 75-kDa molecular weight representing the SGLT2 level of protein expression in HEPTECs isolated from type 2 diabetes increases up to three times compared with healthy volunteers. GLUT2 (55 kDa) level of protein expression in HEPTECs isolated from type 2 diabetes increases up to 10 times compared with healthy volunteers. The level of glucose transporter protein expression is determined from densitometry relative to GAPDH. Values are means ± SE (n = 4; *P < 0.05).

This Article

  1. Diabetes vol. 54 no. 12 3427-3434