Table of Contents

Rapid Publications

Select this article
- Suzanne J. Micallef,
- Mary E. Janes,
- Kathy Knezevic,
- Richard P. Davis,
- Andrew G. Elefanty,
- and Edouard G. Stanley
Retinoic Acid Induces Pdx1-Positive Endoderm in Differentiating Mouse Embryonic Stem Cells
Diabetes February 2005 54:301-305; published ahead of print December 7, 2004, doi:10.2337/diabetes.54.2.301
Select this article
- Elmar Jaeckel,
- Harald von Boehmer,
- and Michael P. Manns
Antigen-Specific FoxP3-Transduced T-Cells Can Control Established Type 1 Diabetes
Diabetes February 2005 54:306-310; published ahead of print December 10, 2004, doi:10.2337/diabetes.54.2.306

Perspective in Diabetes

Select this article
- Barry J. Goldstein,
- Kalyankar Mahadev,
- and Xiangdong Wu
Redox Paradox: Insulin Action Is Facilitated by Insulin-Stimulated Reactive Oxygen Species With Multiple Potential Signaling Targets
Diabetes February 2005 54:311-321; doi:10.2337/diabetes.54.2.311
Select this article
- Yasushi Ishigaki,
- Hideki Katagiri,
- Tetsuya Yamada,
- Takehide Ogihara,
- Junta Imai,
- Kenji Uno,
- Yutaka Hasegawa,
- Junhong Gao,
- Hisamitsu Ishihara,
- Tooru Shimosegawa,
- Hideyuki Sakoda,
- Tomoichiro Asano,
- and Yoshitomo Oka
Dissipating Excess Energy Stored in the Liver Is a Potential Treatment Strategy for Diabetes Associated With Obesity
Diabetes February 2005 54:322-332; doi:10.2337/diabetes.54.2.322
Select this article
- Steven E. Stern,
- Ken Williams,
- Eleuterio Ferrannini,
- Ralph A. DeFronzo,
- Clifton Bogardus,
- and Michael P. Stern
Identification of Individuals With Insulin Resistance Using Routine Clinical Measurements
Diabetes February 2005 54:333-339; doi:10.2337/diabetes.54.2.333
Select this article
- Darcy B. Carr,
- Kristina M. Utzschneider,
- Edward J. Boyko,
- Pamela J. Asberry,
- Rebecca L. Hull,
- Keiichi Kodama,
- Holly S. Callahan,
- Colleen C. Matthys,
- Donna L. Leonetti,
- Robert S. Schwartz,
- Steven E. Kahn,
- and Wilfred Y. Fujimoto
A Reduced-Fat Diet and Aerobic Exercise in Japanese Americans With Impaired Glucose Tolerance Decreases Intra-Abdominal Fat and Improves Insulin Sensitivity but not β-Cell Function
Diabetes February 2005 54:340-347; doi:10.2337/diabetes.54.2.340

Signal Transduction

Select this article
- Robert Ducroc,
- Sandra Guilmeau,
- Khalil Akasbi,
- Hélène Devaud,
- Marion Buyse,
- and André Bado
Luminal Leptin Induces Rapid Inhibition of Active Intestinal Absorption of Glucose Mediated by Sodium-Glucose Cotransporter 1
Diabetes February 2005 54:348-354; doi:10.2337/diabetes.54.2.348
Select this article
- R. Richard Pencek,
- Jane Shearer,
- Raul C. Camacho,
- Freyja D. James,
- D. Brooks Lacy,
- Patrick T. Fueger,
- E. Patrick Donahue,
- Wanda Snead,
- and David H. Wasserman
5-Aminoimidazole-4-Carboxamide-1-β-d-Ribofuranoside Causes Acute Hepatic Insulin Resistance In Vivo
Diabetes February 2005 54:355-360; doi:10.2337/diabetes.54.2.355
Select this article
- Anita M. Hennige,
- Rainer Lehmann,
- Cora Weigert,
- Klaus Moeschel,
- Myriam Schäuble,
- Elisabeth Metzinger,
- Reiner Lammers,
- and Hans-Ulrich Häring
Insulin Glulisine: Insulin Receptor Signaling Characteristics In Vivo
Diabetes February 2005 54:361-366; doi:10.2337/diabetes.54.2.361
Select this article
- Hengjiang Dong,
- Betty A. Maddux,
- Jennifer Altomonte,
- Marcia Meseck,
- Domenico Accili,
- Robert Terkeltaub,
- Kristen Johnson,
- Jack F. Youngren,
- and Ira D. Goldfine
Increased Hepatic Levels of the Insulin Receptor Inhibitor, PC-1/NPP1, Induce Insulin Resistance and Glucose Intolerance
Diabetes February 2005 54:367-372; doi:10.2337/diabetes.54.2.367
Select this article
- Raul C. Camacho,
- R. Richard Pencek,
- D. Brooks Lacy,
- Freyja D. James,
- E. Patrick Donahue,
- and David H. Wasserman
Portal Venous 5-Aminoimidazole-4-Carboxamide-1-β-d-Ribofuranoside Infusion Overcomes Hyperinsulinemic Suppression of Endogenous Glucose Output
Diabetes February 2005 54:373-382; doi:10.2337/diabetes.54.2.373
Select this article
- Sofija Jovanović and
- Aleksandar Jovanović
High Glucose Regulates the Activity of Cardiac Sarcolemmal ATP-Sensitive K⁺ Channels via 1,3-Bisphosphoglycerate: A Novel Link Between Cardiac Membrane Excitability and Glucose Metabolism
Diabetes February 2005 54:383-393; doi:10.2337/diabetes.54.2.383
Select this article
- Alessandra Modesti,
- Iacopo Bertolozzi,
- Tania Gamberi,
- Matilde Marchetta,
- Camilla Lumachi,
- Mirella Coppo,
- Federico Moroni,
- Thomas Toscano,
- Gianluca Lucchese,
- Gian F. Gensini,
- and Pietro A. Modesti
Hyperglycemia Activates JAK2 Signaling Pathway in Human Failing Myocytes via Angiotensin II–Mediated Oxidative Stress
Diabetes February 2005 54:394-401; doi:10.2337/diabetes.54.2.394

Obesity Studies

Select this article
- Frédéric Bost,
- Myriam Aouadi,
- Leslie Caron,
- Patrick Even,
- Nathalie Belmonte,
- Matthieu Prot,
- Christian Dani,
- Paul Hofman,
- Gilles Pagès,
- Jacques Pouysségur,
- Yannick Le Marchand-Brustel,
- and Bernard Binétruy
The Extracellular Signal–Regulated Kinase Isoform ERK1 Is Specifically Required for In Vitro and In Vivo Adipogenesis
Diabetes February 2005 54:402-411; doi:10.2337/diabetes.54.2.402
Select this article
- Takashi Ide
Interaction of Fish Oil and Conjugated Linoleic Acid in Affecting Hepatic Activity of Lipogenic Enzymes and Gene Expression in Liver and Adipose Tissue
Diabetes February 2005 54:412-423; doi:10.2337/diabetes.54.2.412

Immunology and Transplantation

Select this article
- Hongxiang Hui,
- Nasif Khoury,
- Xiaoning Zhao,
- Levent Balkir,
- Eugenio D’Amico,
- Angela Bullotta,
- Elizabeth D. Nguyen,
- Andrea Gambotto,
- and Riccardo Perfetti
Adenovirus-Mediated XIAP Gene Transfer Reverses the Negative Effects of Immunosuppressive Drugs on Insulin Secretion and Cell Viability of Isolated Human Islets
Diabetes February 2005 54:424-433; doi:10.2337/diabetes.54.2.424
Select this article
- Raymond J. Steptoe,
- Janine M. Ritchie,
- Lynelle K. Jones,
- and Leonard C. Harrison
Autoimmune Diabetes Is Suppressed by Transfer of Proinsulin-Encoding Gr-1⁺ Myeloid Progenitor Cells That Differentiate In Vivo Into Resting Dendritic Cells
Diabetes February 2005 54:434-442; doi:10.2337/diabetes.54.2.434
Select this article
- Gina R. Rayat and
- Ronald G. Gill
Indefinite Survival of Neonatal Porcine Islet Xenografts by Simultaneous Targeting of LFA-1 and CD154 or CD45RB
Diabetes February 2005 54:443-451; doi:10.2337/diabetes.54.2.443

Islet Studies

Select this article
- Alessandra K. Cardozo,
- Fernanda Ortis,
- Joachim Storling,
- Ying-Mei Feng,
- Joanne Rasschaert,
- Morten Tonnesen,
- Françoise Van Eylen,
- Thomas Mandrup-Poulsen,
- André Herchuelz,
- and Décio L. Eizirik
Cytokines Downregulate the Sarcoendoplasmic Reticulum Pump Ca²⁺ ATPase 2b and Deplete Endoplasmic Reticulum Ca²⁺, Leading to Induction of Endoplasmic Reticulum Stress in Pancreatic β-Cells
Diabetes February 2005 54:452-461; doi:10.2337/diabetes.54.2.452
Select this article
- Laura Herrero,
- Blanca Rubí,
- David Sebastián,
- Dolors Serra,
- Guillermina Asins,
- Pierre Maechler,
- Marc Prentki,
- and Fausto G. Hegardt
Alteration of the Malonyl-CoA/Carnitine Palmitoyltransferase I Interaction in the β-Cell Impairs Glucose-Induced Insulin Secretion
Diabetes February 2005 54:462-471; doi:10.2337/diabetes.54.2.462
Select this article
- Houtan Noushmehr,
- Eugenio D’Amico,
- Loredana Farilla,
- Hongxiang Hui,
- Kolja A. Wawrowsky,
- Wojciech Mlynarski,
- Alessandro Doria,
- Nada A. Abumrad,
- and Riccardo Perfetti
Fatty Acid Translocase (FAT/CD36) Is Localized on Insulin-Containing Granules in Human Pancreatic β-Cells and Mediates Fatty Acid Effects on Insulin Secretion
Diabetes February 2005 54:472-481; doi:10.2337/diabetes.54.2.472
Select this article
- Yazhou Li,
- Xiemin Cao,
- Li-Xin Li,
- Patricia L. Brubaker,
- Helena Edlund,
- and Daniel J. Drucker
β-Cell Pdx1 Expression Is Essential for the Glucoregulatory, Proliferative, and Cytoprotective Actions of Glucagon-Like Peptide-1
Diabetes February 2005 54:482-491; doi:10.2337/diabetes.54.2.482
Select this article
- Akimitsu Takahashi,
- Kaori Motomura,
- Toyonori Kato,
- Tomohiro Yoshikawa,
- Yoshimi Nakagawa,
- Naoya Yahagi,
- Hirohito Sone,
- Hiroaki Suzuki,
- Hideo Toyoshima,
- Nobuhiro Yamada,
- and Hitoshi Shimano
Transgenic Mice Overexpressing Nuclear SREBP-1c in Pancreatic β-Cells
Diabetes February 2005 54:492-499; doi:10.2337/diabetes.54.2.492

Pathophysiology

Select this article
- Sang Won Suh,
- Yang Fan,
- Shwuhuey M. Hong,
- Zhengyan Liu,
- Yasuhiko Matsumori,
- Philip R. Weinstein,
- Raymond A. Swanson,
- and Jialing Liu
Hypoglycemia Induces Transient Neurogenesis and Subsequent Progenitor Cell Loss in the Rat Hippocampus
Diabetes February 2005 54:500-509; doi:10.2337/diabetes.54.2.500
Select this article
- Tina I. Lam,
- Steven E. Anderson,
- Nicole Glaser,
- and Martha E. O’Donnell
Bumetanide Reduces Cerebral Edema Formation in Rats With Diabetic Ketoacidosis
Diabetes February 2005 54:510-516; doi:10.2337/diabetes.54.2.510

Complications

Select this article
- Georgian T. Mustata,
- Mariana Rosca,
- Klaus M. Biemel,
- Oliver Reihl,
- Mark A. Smith,
- Ashwini Viswanathan,
- Christopher Strauch,
- Yunpeng Du,
- Jie Tang,
- Timothy S. Kern,
- Markus O. Lederer,
- Michael Brownlee,
- Miriam F. Weiss,
- and Vincent M. Monnier
Paradoxical Effects of Green Tea (Camellia Sinensis) and Antioxidant Vitamins in Diabetic Rats: Improved Retinopathy and Renal Mitochondrial Defects but Deterioration of Collagen Matrix Glycoxidation and Cross-Linking
Diabetes February 2005 54:517-526; doi:10.2337/diabetes.54.2.517
Select this article
- Ronald Klein,
- Bernard Zinman,
- Robert Gardiner,
- Samy Suissa,
- Sandra M. Donnelly,
- Alan R. Sinaiko,
- Michael S. Kramer,
- Paul Goodyer,
- Scot E. Moss,
- Trudy Strand,
- and Michael Mauer
The Relationship of Diabetic Retinopathy to Preclinical Diabetic Glomerulopathy Lesions in Type 1 Diabetic Patients: The Renin-Angiotensin System Study
Diabetes February 2005 54:527-533; doi:10.2337/diabetes.54.2.527
Select this article
- Matthias B. Schulze,
- Iris Shai,
- Eric B. Rimm,
- Tricia Li,
- Nader Rifai,
- and Frank B. Hu
Adiponectin and Future Coronary Heart Disease Events Among Men With Type 2 Diabetes
Diabetes February 2005 54:534-539; doi:10.2337/diabetes.54.2.534
Select this article
- Haikun Li,
- Sabine Télémaque,
- Richard E. Miller,
- and James D. Marsh
High Glucose Inhibits Apoptosis Induced by Serum Deprivation in Vascular Smooth Muscle Cells via Upregulation of Bcl-2 and Bcl-xl
Diabetes February 2005 54:540-545; doi:10.2337/diabetes.54.2.540
Select this article
- Parri Wentzel,
- Mattias Gäreskog,
- and Ulf J. Eriksson
Folic Acid Supplementation Diminishes Diabetes- and Glucose-Induced Dysmorphogenesis in Rat Embryos In Vivo and In Vitro
Diabetes February 2005 54:546-553; doi:10.2337/diabetes.54.2.546

Pharmacology and Therapeutics

Select this article
- Tian-Li Yue,
- Weike Bao,
- Juan-Li Gu,
- Jianqi Cui,
- Ling Tao,
- Xin-Liang Ma,
- Eliot H. Ohlstein,
- and Beat M. Jucker
Rosiglitazone Treatment in Zucker Diabetic Fatty Rats Is Associated With Ameliorated Cardiac Insulin Resistance and Protection From Ischemia/Reperfusion-Induced Myocardial Injury
Diabetes February 2005 54:554-562; doi:10.2337/diabetes.54.2.554
Select this article
- Valma Harjutsalo,
- Toomas Podar,
- and Jaakko Tuomilehto
Cumulative Incidence of Type 1 Diabetes in 10,168 Siblings of Finnish Young-Onset Type 1 Diabetic Patients
Diabetes February 2005 54:563-569; doi:10.2337/diabetes.54.2.563
Select this article
- Gunnar Engström,
- Bo Hedblad,
- Karl-Fredrik Eriksson,
- Lars Janzon,
- and Folke Lindgärde
Complement C3 Is a Risk Factor for the Development of Diabetes: A Population-Based Cohort Study
Diabetes February 2005 54:570-575; doi:10.2337/diabetes.54.2.570
Select this article
- Michael N. Weedon,
- Timothy M. Frayling,
- Beverley Shields,
- Beatrice Knight,
- Tina Turner,
- Bradley S. Metcalf,
- Linda Voss,
- Terence J. Wilkin,
- Anne McCarthy,
- Yoav Ben-Shlomo,
- George Davey Smith,
- Sue Ring,
- Richard Jones,
- Jean Golding,
- Liisa Byberg,
- Vera Mann,
- Tomas Axelsson,
- Ann-Christine Syvänen,
- David Leon,
- and Andrew T. Hattersley
Genetic Regulation of Birth Weight and Fasting Glucose by a Common Polymorphism in the Islet Cell Promoter of the Glucokinase Gene
Diabetes February 2005 54:576-581; doi:10.2337/diabetes.54.2.576

Brief Genetics Report

Select this article
- David M. Flavell,
- Helen Ireland,
- Jeffrey W. Stephens,
- Emma Hawe,
- Jay Acharya,
- Hugh Mather,
- Steven J. Hurel,
- and Steve E. Humphries
Peroxisome Proliferator-Activated Receptor α Gene Variation Influences Age of Onset and Progression of Type 2 Diabetes
Diabetes February 2005 54:582-586; doi:10.2337/diabetes.54.2.582

Errata

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Errata
Diabetes February 2005 54:587; doi:10.2337/diabetes.54.2.587
Select this article

Errata
Diabetes February 2005 54:587; doi:10.2337/diabetes.54.2.587-a

Diabetes

Rapid Publications

Retinoic Acid Induces Pdx1-Positive Endoderm in Differentiating Mouse Embryonic Stem Cells

Antigen-Specific FoxP3-Transduced T-Cells Can Control Established Type 1 Diabetes

Perspective in Diabetes

Redox Paradox: Insulin Action Is Facilitated by Insulin-Stimulated Reactive Oxygen Species With Multiple Potential Signaling Targets

Dissipating Excess Energy Stored in the Liver Is a Potential Treatment Strategy for Diabetes Associated With Obesity

Identification of Individuals With Insulin Resistance Using Routine Clinical Measurements

A Reduced-Fat Diet and Aerobic Exercise in Japanese Americans With Impaired Glucose Tolerance Decreases Intra-Abdominal Fat and Improves Insulin Sensitivity but not β-Cell Function

Signal Transduction

Luminal Leptin Induces Rapid Inhibition of Active Intestinal Absorption of Glucose Mediated by Sodium-Glucose Cotransporter 1

5-Aminoimidazole-4-Carboxamide-1-β-d-Ribofuranoside Causes Acute Hepatic Insulin Resistance In Vivo

Insulin Glulisine: Insulin Receptor Signaling Characteristics In Vivo

Increased Hepatic Levels of the Insulin Receptor Inhibitor, PC-1/NPP1, Induce Insulin Resistance and Glucose Intolerance

Portal Venous 5-Aminoimidazole-4-Carboxamide-1-β-d-Ribofuranoside Infusion Overcomes Hyperinsulinemic Suppression of Endogenous Glucose Output

High Glucose Regulates the Activity of Cardiac Sarcolemmal ATP-Sensitive K+ Channels via 1,3-Bisphosphoglycerate: A Novel Link Between Cardiac Membrane Excitability and Glucose Metabolism

Hyperglycemia Activates JAK2 Signaling Pathway in Human Failing Myocytes via Angiotensin II–Mediated Oxidative Stress

Obesity Studies

The Extracellular Signal–Regulated Kinase Isoform ERK1 Is Specifically Required for In Vitro and In Vivo Adipogenesis

Interaction of Fish Oil and Conjugated Linoleic Acid in Affecting Hepatic Activity of Lipogenic Enzymes and Gene Expression in Liver and Adipose Tissue

Immunology and Transplantation

Adenovirus-Mediated XIAP Gene Transfer Reverses the Negative Effects of Immunosuppressive Drugs on Insulin Secretion and Cell Viability of Isolated Human Islets

Autoimmune Diabetes Is Suppressed by Transfer of Proinsulin-Encoding Gr-1+ Myeloid Progenitor Cells That Differentiate In Vivo Into Resting Dendritic Cells

Indefinite Survival of Neonatal Porcine Islet Xenografts by Simultaneous Targeting of LFA-1 and CD154 or CD45RB

Islet Studies

Cytokines Downregulate the Sarcoendoplasmic Reticulum Pump Ca2+ ATPase 2b and Deplete Endoplasmic Reticulum Ca2+, Leading to Induction of Endoplasmic Reticulum Stress in Pancreatic β-Cells

Alteration of the Malonyl-CoA/Carnitine Palmitoyltransferase I Interaction in the β-Cell Impairs Glucose-Induced Insulin Secretion

Fatty Acid Translocase (FAT/CD36) Is Localized on Insulin-Containing Granules in Human Pancreatic β-Cells and Mediates Fatty Acid Effects on Insulin Secretion

β-Cell Pdx1 Expression Is Essential for the Glucoregulatory, Proliferative, and Cytoprotective Actions of Glucagon-Like Peptide-1

Transgenic Mice Overexpressing Nuclear SREBP-1c in Pancreatic β-Cells

Pathophysiology

Hypoglycemia Induces Transient Neurogenesis and Subsequent Progenitor Cell Loss in the Rat Hippocampus

Bumetanide Reduces Cerebral Edema Formation in Rats With Diabetic Ketoacidosis

Complications

Paradoxical Effects of Green Tea (Camellia Sinensis) and Antioxidant Vitamins in Diabetic Rats: Improved Retinopathy and Renal Mitochondrial Defects but Deterioration of Collagen Matrix Glycoxidation and Cross-Linking

The Relationship of Diabetic Retinopathy to Preclinical Diabetic Glomerulopathy Lesions in Type 1 Diabetic Patients: The Renin-Angiotensin System Study

Adiponectin and Future Coronary Heart Disease Events Among Men With Type 2 Diabetes

High Glucose Inhibits Apoptosis Induced by Serum Deprivation in Vascular Smooth Muscle Cells via Upregulation of Bcl-2 and Bcl-xl

Folic Acid Supplementation Diminishes Diabetes- and Glucose-Induced Dysmorphogenesis in Rat Embryos In Vivo and In Vitro

Pharmacology and Therapeutics

Rosiglitazone Treatment in Zucker Diabetic Fatty Rats Is Associated With Ameliorated Cardiac Insulin Resistance and Protection From Ischemia/Reperfusion-Induced Myocardial Injury

Cumulative Incidence of Type 1 Diabetes in 10,168 Siblings of Finnish Young-Onset Type 1 Diabetic Patients

Complement C3 Is a Risk Factor for the Development of Diabetes: A Population-Based Cohort Study

Genetic Regulation of Birth Weight and Fasting Glucose by a Common Polymorphism in the Islet Cell Promoter of the Glucokinase Gene

Brief Genetics Report

Peroxisome Proliferator-Activated Receptor α Gene Variation Influences Age of Onset and Progression of Type 2 Diabetes

Errata

Errata

Errata

This Issue

Current Issue

High Glucose Regulates the Activity of Cardiac Sarcolemmal ATP-Sensitive K⁺ Channels via 1,3-Bisphosphoglycerate: A Novel Link Between Cardiac Membrane Excitability and Glucose Metabolism

Autoimmune Diabetes Is Suppressed by Transfer of Proinsulin-Encoding Gr-1⁺ Myeloid Progenitor Cells That Differentiate In Vivo Into Resting Dendritic Cells

Cytokines Downregulate the Sarcoendoplasmic Reticulum Pump Ca²⁺ ATPase 2b and Deplete Endoplasmic Reticulum Ca²⁺, Leading to Induction of Endoplasmic Reticulum Stress in Pancreatic β-Cells