Pulsatile Insulin Secretion Dictates Systemic Insulin Delivery by Regulating Hepatic Insulin Extraction In Humans

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

FIG. 2.
FIG. 2.

Calculated C-peptide secretion rates (A) and insulin delivery rates from the liver (B) in five healthy subjects studied in the fasting state and during an intravenous glucose infusion (2 mg · kg−1 · min−1). Values are presented as means ± SEM (n = 5). P values were calculated by repeated-measures ANOVA.

This Article

  1. Diabetes vol. 54 no. 6 1649-1656