Pulsatile Insulin Secretion Dictates Systemic Insulin Delivery by Regulating Hepatic Insulin Extraction In Humans

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FIG. 3.
FIG. 3.

Absolute hepatic clearance rates (A) and fractional insulin extraction (B) in five healthy subjects studied in the fasting state and during an intravenous glucose infusion (2 mg · kg−1 · min−1). Data represent means of 40 individual values in each subject during the respective experimental periods. P values were calculated by paired ANOVA.

This Article

  1. Diabetes vol. 54 no. 6 1649-1656