Insulin and Leptin Resistance With Hyperleptinemia in Mice Lacking Androgen Receptor

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FIG. 1.
FIG. 1.

The AR−/y mice developed excess adiposity. A: Growth curves of mice were determined at indicated time points between the ages of 5 and 40 weeks. Values are the means ± SE from 9–10 mice per group. *P < 0.05, **P < 0.01, AR−/y vs. male wild-type (WT) mice. B: Epididymal and perirenal fat pads isolated from 35-week-old mice (upper panels). Sections of WAT are shown at 40× magnification (lower panels) of 35-week-old mice (scale bar = 200 μm). C: Distribution of cell size of epididymal WAT from 35-week-old mice.

This Article

  1. Diabetes vol. 54 no. 6 1717-1725