A Human-Specific Role of Cell Death-Inducing DFFA (DNA Fragmentation Factor-α)-Like Effector A (CIDEA) in Adipocyte Lipolysis and Obesity

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FIG. 1.
FIG. 1.

CIDEA in human WAT. A: Ratios of CIDEA to β-2 microglobulin (β2-MG) mRNA levels in WAT and isolated adipocytes from nonobese (n = 8) (⧫) and obese (n = 9) (○) men and women. P < 0.001, Spearman’s correlation. B: Ratios of CIDEA and GAPDH to β2-MG mRNA levels in WAT from obese (n = 143) (□) and nonobese (n = 43) (▪) subjects. C and D: BMI (C) and ratios of CIDEA to β2-MG adipose mRNA levels (D) in 12 obese subjects before (□) and after (▪) weight reduction. *P < 0.05 and **P < 0.01, Wilcoxon’s signed-rank test; ***P < 0.001, Mann-Whitney U test.

This Article

  1. Diabetes vol. 54 no. 6 1726-1734