β-Cell Function Across the Spectrum of Glucose Tolerance in Obese Youth

TABLE 2

Fasting biochemical values

NGT IGT Type 2 diabetes P value
Glucose (mmol/l) 5.27 ± 0.09 5.32 ± 0.09 5.71 ± 0.21 0.07
Insulin (mU/l) 33.2 ± 2.4 40.0 ± 3.5 36.8 ± 3.6 0.36
C-peptide (nmol/l) 1.12 ± 0.07 1.33 ± 0.08 1.11 ± 0.02 0.23
HbA1c (%) 5.2 ± 0.3 5.4 ± 0.4 7.1 ± 1.6* P <0.001
Proinsulin (pmol/l) 26 ± 2 34 ± 5 33 ± 7 0.22
Proinsulin-to-insulin ratio 0.80 ± 0.31 0.78 ± 0.30 1.07 ± 0.64 0.17
Triglicerides (mg/dl) 98 ± 8 119 ± 13 128 ± 27 0.25
Free fatty acids 545 ± 222 528 ± 125 480 ± 111 0.62
  • Data are means ± SE.

This Article

  1. Diabetes vol. 54 no. 6 1735-1743