Effect of GCCR ASO treatment on circulating lipids in ZDF and HFD-STZ rats. Rats were dosed with saline (□), GCCR ASO 37.5
mg/kg (▪), or control ASO 37.5 mg/kg ([cjs2112]) subcutaneously twice a week for 4 weeks. Blood samples were collected at
the end of the study in the fed state, and lipids were analyzed as described in research design and methods. Data are expressed as means ± SE. *P < 0.05, GCCR ASO treatment vs. saline treatment.