Frequency of HLA genotypes within the BABYDIAB cohort. Children are grouped according to their islet autoantibody status,
and HLA genotypes are grouped according to their conferred type 1 diabetes risk. Children who develop multiple islet autoantibodies
(Multiple Abs pos) have HLA genotypes that are found in type 1 diabetes, whereas children who developed single antibodies
(Single Ab pos) had HLA genotypes similar to children who were autoantibody negative (Ab neg). Single autoantibody–positive
children have few type 1 diabetes risk genotypes.