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Comment on: Buchanan (2007) (How) Can We Prevent Type 2 Diabetes? Diabetes 56:1502–1507

  1. Lawrence S. Phillips
  1. From the Division of Endocrinology and Metabolism, Emory University School of Medicine and VA Medical Center, Atlanta, Georgia
  1. Address correspondence to Lawrence S. Phillips, MD, Division of Endocrinology, Emory University, 101 Woodruff Circle, WMRB Room 1027, Atlanta, GA 30322. E-mail: lawrence.phillips{at}emory.edu

In Dr. Buchanan's excellent review (1), he presents a novel approach to analysis of diabetes prevention trial outcomes based on “absolute differences” in the percentage of intervention versus control subjects who develop diabetes. In his analysis, rising absolute differences in the conversion from pre-diabetes to diabetes reflect “prevention,” while stable absolute differences reflect “delay/masking.” I believe that readers …

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