Table of Contents

December 2007; 56 (12)

Online Letters to the Editor

Select this article
- Toshiyuki Saito,
- Hideaki Hayashida,
- and Reiko Furugen
Comment on: Cani et al. (2007) Metabolic Endotoxemia Initiates Obesity and Insulin Resistance: Diabetes 56:1761–1772
Diabetes December 2007 56:e20; doi:10.2337/db07-1181
Select this article
- Rémy Burcelin,
- Patrice D. Cani,
- and Jacques Amar
Response to Comment on: Cani et al. (2007) Metabolic Endotoxemia Initiates Obesity and Insulin Resistance: Diabetes 56:1761–1772
Diabetes December 2007 56:e21; doi:10.2337/db07-1262
Select this article
- Chee-Seng Ku,
- Moira Khaw,
- and Kee Seng Chia
Comment on: Chang et al. (2007) Association Study of the Genetic Polymorphisms of the Transcription Factor 7-like 2 (TCF7L2) Gene and Type 2 Diabetes in the Chinese Population: Diabetes 56:2631–2637
Diabetes December 2007 56:e22; doi:10.2337/db07-1213
Select this article
- Yi-Cheng Chang,
- Ken C. Chiu,
- and Lee-Ming Chuang
Response to Comment on: Chang et al. (2007) Association Study of the Genetic Polymorphisms of the Transcription Factor 7-like 2 (TCF7L2) Gene and Type 2 Diabetes in the Chinese Population: Diabetes 56:2631–2637
Diabetes December 2007 56:e23; doi:10.2337/db07-1302

Editorial

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- James Levine
Lost in Translation: Facing Up to Translational Research
Diabetes December 2007 56:2841; doi:10.2337/db07-1371

Commentaries

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- Karen Reue and
- Jimmy Donkor
Genetic Factors in Type 2 Diabetes: All in the (Lipin) Family
Diabetes December 2007 56:2842-2843; doi:10.2337/db07-1288
Select this article
- Kent D. Taylor,
- Jill M. Norris,
- and Jerome I. Rotter
Genome-Wide Association: Which Do You Want First: the Good News, the Bad News, or the Good News?
Diabetes December 2007 56:2844-2848; doi:10.2337/db07-1324

Metabolism

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- Rutger W. van der Meer,
- Sebastiaan Hammer,
- Johannes W.A. Smit,
- Marijke Frölich,
- Jeroen J. Bax,
- Michaela Diamant,
- Luuk J. Rijzewijk,
- Albert de Roos,
- Johannes A. Romijn,
- and Hildo J. Lamb
Short-Term Caloric Restriction Induces Accumulation of Myocardial Triglycerides and Decreases Left Ventricular Diastolic Function in Healthy Subjects
Diabetes December 2007 56:2849-2853; published ahead of print August 23, 2007, doi:10.2337/db07-0768
Select this article
- Henning F. Kramer,
- Eric B. Taylor,
- Carol A. Witczak,
- Nobuharu Fujii,
- Michael F. Hirshman,
- and Laurie J. Goodyear
Calmodulin-Binding Domain of AS160 Regulates Contraction- but Not Insulin-Stimulated Glucose Uptake in Skeletal Muscle
Diabetes December 2007 56:2854-2862; published ahead of print August 23, 2007, doi:10.2337/db07-0681
Select this article
- Debby P.Y. Koonen,
- René L. Jacobs,
- Maria Febbraio,
- Martin E. Young,
- Carrie-Lynn M. Soltys,
- Huy Ong,
- Dennis E. Vance,
- and Jason R.B. Dyck
Increased Hepatic CD36 Expression Contributes to Dyslipidemia Associated With Diet-Induced Obesity
Diabetes December 2007 56:2863-2871; published ahead of print August 29, 2007, doi:10.2337/db07-0907
Select this article
- Cendrine Cabou,
- Patrice D. Cani,
- Gérard Campistron,
- Claude Knauf,
- Caroline Mathieu,
- Claudio Sartori,
- Jacques Amar,
- Urs Scherrer,
- and Rémy Burcelin
Central Insulin Regulates Heart Rate and Arterial Blood Flow: An Endothelial Nitric Oxide Synthase–Dependent Mechanism Altered During Diabetes
Diabetes December 2007 56:2872-2877; published ahead of print September 5, 2007, doi:10.2337/db07-0115
Select this article
- Robert H. Nelson,
- Rita Basu,
- C. Michael Johnson,
- Robert A. Rizza,
- and John M. Miles
Splanchnic Spillover of Extracellular Lipase–Generated Fatty Acids in Overweight and Obese Humans
Diabetes December 2007 56:2878-2884; published ahead of print September 19, 2007, doi:10.2337/db07-0812
Select this article
- Renee M. Ross,
- Glenn D. Wadley,
- Michael G. Clark,
- Stephen Rattigan,
- and Glenn K. McConell
Local Nitric Oxide Synthase Inhibition Reduces Skeletal Muscle Glucose Uptake but Not Capillary Blood Flow During In Situ Muscle Contraction in Rats
Diabetes December 2007 56:2885-2892; published ahead of print September 19, 2007, doi:10.2337/db07-0745

Signal Transduction

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- María García-Fernández,
- Patricia Ortega-Sáenz,
- Antonio Castellano,
- and José López-Barneo
Mechanisms of Low-Glucose Sensitivity in Carotid Body Glomus Cells
Diabetes December 2007 56:2893-2900; published ahead of print September 7, 2007, doi:10.2337/db07-0122
Select this article
- Ning-Chun Liu,
- Wen-Jye Lin,
- Eungseok Kim,
- Loretta L. Collins,
- Hung-Yun Lin,
- I-Chen Yu,
- Janet D. Sparks,
- Lu-Min Chen,
- Yi-Fen Lee,
- and Chawnshang Chang
Loss of TR4 Orphan Nuclear Receptor Reduces Phosphoenolpyruvate Carboxykinase–Mediated Gluconeogenesis
Diabetes December 2007 56:2901-2909; published ahead of print September 7, 2007, doi:10.2337/db07-0359

Obesity Studies

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- Katherine J. Strissel,
- Zlatina Stancheva,
- Hideaki Miyoshi,
- James W. Perfield II,
- Jason DeFuria,
- Zoe Jick,
- Andrew S. Greenberg,
- and Martin S. Obin
Adipocyte Death, Adipose Tissue Remodeling, and Obesity Complications
Diabetes December 2007 56:2910-2918; published ahead of print September 11, 2007, doi:10.2337/db07-0767

Immunology and Transplantation

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- Suzanne D. Burke,
- Hongmei Dong,
- Aleah D. Hazan,
- and B. Anne Croy
Aberrant Endometrial Features of Pregnancy in Diabetic NOD Mice
Diabetes December 2007 56:2919-2926; published ahead of print September 7, 2007, doi:10.2337/db07-0773

Islet Studies

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- Andrei I. Oprescu,
- George Bikopoulos,
- Anthony Naassan,
- Emma M. Allister,
- Christine Tang,
- Edward Park,
- Hiroshi Uchino,
- Gary F. Lewis,
- I. George Fantus,
- Maria Rozakis-Adcock,
- Michael B. Wheeler,
- and Adria Giacca
Free Fatty Acid–Induced Reduction in Glucose-Stimulated Insulin Secretion: Evidence for a Role of Oxidative Stress In Vitro and In Vivo
Diabetes December 2007 56:2927-2937; published ahead of print August 23, 2007, doi:10.2337/db07-0075
Select this article
- Francis C. Lynn,
- Peter Skewes-Cox,
- Yasuhiro Kosaka,
- Michael T. McManus,
- Brian D. Harfe,
- and Michael S. German
MicroRNA Expression Is Required for Pancreatic Islet Cell Genesis in the Mouse
Diabetes December 2007 56:2938-2945; published ahead of print September 5, 2007, doi:10.2337/db07-0175
Select this article
- Tatsuya Yano,
- Zhengyu Liu,
- Jennifer Donovan,
- Melissa K. Thomas,
- and Joel F. Habener
Stromal Cell–Derived Factor-1 (SDF-1)/CXCL12 Attenuates Diabetes in Mice and Promotes Pancreatic β-Cell Survival by Activation of the Prosurvival Kinase Akt
Diabetes December 2007 56:2946-2957; published ahead of print September 18, 2007, doi:10.2337/db07-0291

Pathophysiology

Select this article
- Emma M. Eggleston,
- Linda A. Jahn,
- and Eugene J. Barrett
Hyperinsulinemia Rapidly Increases Human Muscle Microvascular Perfusion but Fails to Increase Muscle Insulin Clearance: Evidence That a Saturable Process Mediates Muscle Insulin Uptake
Diabetes December 2007 56:2958-2963; published ahead of print August 24, 2007, doi:10.2337/db07-0670
Select this article
- Paul W. Franks,
- Robert L. Hanson,
- William C. Knowler,
- Carol Moffett,
- Gleebah Enos,
- Aniello M. Infante,
- Jonathan Krakoff,
- and Helen C. Looker
Childhood Predictors of Young-Onset Type 2 Diabetes
Diabetes December 2007 56:2964-2972; published ahead of print August 24, 2007, doi:10.2337/db06-1639
Select this article
- Eun Hee Koh,
- Joong-Yeol Park,
- Hye-Sun Park,
- Min Jae Jeon,
- Je Won Ryu,
- Mina Kim,
- Sun Young Kim,
- Min-Seon Kim,
- Seung-Whan Kim,
- In Sun Park,
- Jang Hyun Youn,
- and Ki-Up Lee
Essential Role of Mitochondrial Function in Adiponectin Synthesis in Adipocytes
Diabetes December 2007 56:2973-2981; published ahead of print September 7, 2007, doi:10.2337/db07-0510
Select this article
- Christoph Daniel,
- Kathrin Schaub,
- Kerstin Amann,
- Jack Lawler,
- and Christian Hugo
Thrombospondin-1 Is an Endogenous Activator of TGF-β in Experimental Diabetic Nephropathy In Vivo
Diabetes December 2007 56:2982-2989; published ahead of print September 18, 2007, doi:10.2337/db07-0551
Select this article
- Erica P. Gunderson,
- Cora E. Lewis,
- Ai-Lin Tsai,
- Vicky Chiang,
- Mercedes Carnethon,
- Charles P. Quesenberry, Jr.,
- and Stephen Sidney
A 20-Year Prospective Study of Childbearing and Incidence of Diabetes in Young Women, Controlling for Glycemia Before Conception: The Coronary Artery Risk Development in Young Adults (CARDIA) Study
Diabetes December 2007 56:2990-2996; published ahead of print September 26, 2007, doi:10.2337/db07-1024

Complications

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- Aaron P. Kellogg,
- Tim D. Wiggin,
- Dennis D. Larkin,
- John M. Hayes,
- Martin J. Stevens,
- and Rodica Pop-Busui
Protective Effects of Cyclooxygenase-2 Gene Inactivation Against Peripheral Nerve Dysfunction and Intraepidermal Nerve Fiber Loss in Experimental Diabetes
Diabetes December 2007 56:2997-3005; published ahead of print August 24, 2007, doi:10.2337/db07-0740

Pharmacology and Therapeutics

Select this article
- Grace Flock,
- Laurie L. Baggio,
- Christine Longuet,
- and Daniel J. Drucker
Incretin Receptors for Glucagon-Like Peptide 1 and Glucose-Dependent Insulinotropic Polypeptide Are Essential for the Sustained Metabolic Actions of Vildagliptin in Mice
Diabetes December 2007 56:3006-3013; published ahead of print August 23, 2007, doi:10.2337/db07-0697
Select this article
- Joseph DiChiara,
- Kevin P. Bliden,
- Udaya S. Tantry,
- Miruais S. Hamed,
- Mark J. Antonino,
- Thomas A. Suarez,
- Oscar Bailon,
- Anand Singla,
- and Paul A. Gurbel
The Effect of Aspirin Dosing on Platelet Function in Diabetic and Nondiabetic Patients: An Analysis From the Aspirin-Induced Platelet Effect (ASPECT) Study
Diabetes December 2007 56:3014-3019; published ahead of print September 11, 2007, doi:10.2337/db07-0707

Current Issue

November 2009, 58 (11)

Online Letters to the Editor

Comment on: Cani et al. (2007) Metabolic Endotoxemia Initiates Obesity and Insulin Resistance: Diabetes 56:1761–1772

Response to Comment on: Cani et al. (2007) Metabolic Endotoxemia Initiates Obesity and Insulin Resistance: Diabetes 56:1761–1772

Comment on: Chang et al. (2007) Association Study of the Genetic Polymorphisms of the Transcription Factor 7-like 2 (TCF7L2) Gene and Type 2 Diabetes in the Chinese Population: Diabetes 56:2631–2637

Response to Comment on: Chang et al. (2007) Association Study of the Genetic Polymorphisms of the Transcription Factor 7-like 2 (TCF7L2) Gene and Type 2 Diabetes in the Chinese Population: Diabetes 56:2631–2637

Editorial

Lost in Translation: Facing Up to Translational Research

Commentaries

Genetic Factors in Type 2 Diabetes: All in the (Lipin) Family

Genome-Wide Association: Which Do You Want First: the Good News, the Bad News, or the Good News?

Metabolism

Short-Term Caloric Restriction Induces Accumulation of Myocardial Triglycerides and Decreases Left Ventricular Diastolic Function in Healthy Subjects

Calmodulin-Binding Domain of AS160 Regulates Contraction- but Not Insulin-Stimulated Glucose Uptake in Skeletal Muscle

Increased Hepatic CD36 Expression Contributes to Dyslipidemia Associated With Diet-Induced Obesity

Central Insulin Regulates Heart Rate and Arterial Blood Flow: An Endothelial Nitric Oxide Synthase–Dependent Mechanism Altered During Diabetes

Splanchnic Spillover of Extracellular Lipase–Generated Fatty Acids in Overweight and Obese Humans

Local Nitric Oxide Synthase Inhibition Reduces Skeletal Muscle Glucose Uptake but Not Capillary Blood Flow During In Situ Muscle Contraction in Rats

Signal Transduction

Mechanisms of Low-Glucose Sensitivity in Carotid Body Glomus Cells

Loss of TR4 Orphan Nuclear Receptor Reduces Phosphoenolpyruvate Carboxykinase–Mediated Gluconeogenesis

Obesity Studies

Adipocyte Death, Adipose Tissue Remodeling, and Obesity Complications

Immunology and Transplantation

Aberrant Endometrial Features of Pregnancy in Diabetic NOD Mice

Islet Studies

Free Fatty Acid–Induced Reduction in Glucose-Stimulated Insulin Secretion: Evidence for a Role of Oxidative Stress In Vitro and In Vivo

MicroRNA Expression Is Required for Pancreatic Islet Cell Genesis in the Mouse

Stromal Cell–Derived Factor-1 (SDF-1)/CXCL12 Attenuates Diabetes in Mice and Promotes Pancreatic β-Cell Survival by Activation of the Prosurvival Kinase Akt

Pathophysiology

Hyperinsulinemia Rapidly Increases Human Muscle Microvascular Perfusion but Fails to Increase Muscle Insulin Clearance: Evidence That a Saturable Process Mediates Muscle Insulin Uptake

Childhood Predictors of Young-Onset Type 2 Diabetes

Essential Role of Mitochondrial Function in Adiponectin Synthesis in Adipocytes

Thrombospondin-1 Is an Endogenous Activator of TGF-β in Experimental Diabetic Nephropathy In Vivo

A 20-Year Prospective Study of Childbearing and Incidence of Diabetes in Young Women, Controlling for Glycemia Before Conception: The Coronary Artery Risk Development in Young Adults (CARDIA) Study

Complications

Protective Effects of Cyclooxygenase-2 Gene Inactivation Against Peripheral Nerve Dysfunction and Intraepidermal Nerve Fiber Loss in Experimental Diabetes

Pharmacology and Therapeutics

Incretin Receptors for Glucagon-Like Peptide 1 and Glucose-Dependent Insulinotropic Polypeptide Are Essential for the Sustained Metabolic Actions of Vildagliptin in Mice

The Effect of Aspirin Dosing on Platelet Function in Diabetic and Nondiabetic Patients: An Analysis From the Aspirin-Induced Platelet Effect (ASPECT) Study

Genetics

LPIN2 Is Associated With Type 2 Diabetes, Glucose Metabolism, and Body Composition

Variants in the Plasmacytoma Variant Translocation Gene (PVT1) Are Associated With End-Stage Renal Disease Attributed to Type 1 Diabetes

Identification of Type 2 Diabetes Genes in Mexican Americans Through Genome-Wide Association Studies

A Search for Variants Associated With Young-Onset Type 2 Diabetes in American Indians in a 100K Genotyping Array

Identification of Novel Candidate Genes for Type 2 Diabetes From a Genome-Wide Association Scan in the Old Order Amish: Evidence for Replication From Diabetes-Related Quantitative Traits and From Independent Populations

A 100K Genome-Wide Association Scan for Diabetes and Related Traits in the Framingham Heart Study: Replication and Integration With Other Genome-Wide Datasets

Interleukin-6 Receptor Gene Variations, Plasma Interleukin-6 Levels, and Type 2 Diabetes in U.S. Women

TCF7L2 Is Not a Major Susceptibility Gene for Type 2 Diabetes in Pima Indians: Analysis of 3,501 Individuals

Variants in the Cav2.3 (α1E) Subunit of Voltage-Activated Ca2+ Channels Are Associated With Insulin Resistance and Type 2 Diabetes in Pima Indians

Effects of Genetic Variation in the Human Retinol Binding Protein-4 Gene (RBP4) on Insulin Resistance and Fat Depot–Specific mRNA Expression

Common Variants of the Novel Type 2 Diabetes Genes CDKAL1 and HHEX/IDE Are Associated With Decreased Pancreatic β-Cell Function

Studies of Association of Variants Near the HHEX, CDKN2A/B, and IGF2BP2 Genes With Type 2 Diabetes and Impaired Insulin Release in 10,705 Danish Subjects: Validation and Extension of Genome-Wide Association Studies

Studies in 3,523 Norwegians and Meta-Analysis in 11,571 Subjects Indicate That Variants in the Hepatocyte Nuclear Factor 4α (HNF4A) P2 Region Are Associated With Type 2 Diabetes in Scandinavians

This Issue

Current Issue

Variants in the Ca_v2.3 (α1E) Subunit of Voltage-Activated Ca²⁺ Channels Are Associated With Insulin Resistance and Type 2 Diabetes in Pima Indians