Comment on: Cani et al. (2007) Metabolic Endotoxemia Initiates Obesity and Insulin Resistance: Diabetes 56:1761–1772

  1. Toshiyuki Saito,
  2. Hideaki Hayashida and
  3. Reiko Furugen
  1. From the Department of Oral Health, Unit of Social Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
  1. Address correspondence and reprint requests to Toshiyuki Saito, Nagasaki University, Oral Health, Unit of Social Medicine, 1-7-1 Sakamoto, Nagasaki 852-8588, Japan. E-mail: syto{at}

The recent article by Cani et al. (1) interests us very much. We have reported that obesity and periodontitis were associated for the first time in 1998 (2). Further study revealed that hepatic impairment was more strongly associated with periodontitis than obesity indexes (3). Our results showed that periodontitis increased with elevated serum …

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