Response to Comment on: Chang et al. (2007) Association Study of the Genetic Polymorphisms of the Transcription Factor 7-like 2 (TCF7L2) Gene and Type 2 Diabetes in the Chinese Population: Diabetes 56:2631–2637
- Yi-Cheng Chang1,
- Ken C. Chiu2 and
- Lee-Ming Chuang3
- 1Department of Internal Medicine, National Taiwan University Hospital Yunlin Branch, Yunlin, Taiwan
- 2Department of Diabetes, Endocrinology, and Metabolism, City of Hope National, Medical Center, Duarte, California
- 3Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
- Address correspondence and reprint requests to Lee-Ming Chuang, MD, PhD, Department of Internal Medicine, National Taiwan University Hospital, 7 Chung-Shan South Rd., Taipei, Taiwan. E-mail: leeming{at}ntu.edu.tw
We appreciate the comments from Ku et al. (1). Although previously genome-wide linkage studies were and, currently, genome-wide association studies are the preferred approaches for the search of genetic causes of complex diseases, such as type 2 diabetes, the candidate gene approach remains a very useful tool as a supplement to the …
