Comment on: Kretowski et al. (2007) Polymorphisms of the Renin-Angiotensin System Genes Predict Progression of Subclinical Coronary Atherosclerosis: Diabetes 56:863–871
- From the Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands
- Address correspondence to Eduard J. van Beers, Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands. E-mail: e.j.vanbeers{at}amc.uva.nl
In their recently published study, Kretowski et al. (1) explored the role of some genetic variants of proteins involved in the renin-angiotensin system, in subjects with type 1 diabetes, as predictors of progression of coronary artery calcification (CAC), a marker of subclinical coronary artery disease. Three polymorphisms were studied: variants of angiotensinogen (AGT) (M235T), ACE (I/D), and angiotensin type 1 …
