Comment on: Lin et al. (2007) SUMO4 M55V Variant Is Associated With Diabetic Nephropathy in Type 2 Diabetes: Diabetes 56:1177–1180
- Gottfried Rudofsky, Jr.,
- Andreas Schlotterer,
- Peter P. Nawroth,
- Angelika Bierhaus and
- Andreas Hamann
- From the Division of Endocrinology and Metabolism, Department of Medicine, University of Heidelberg, Heidelberg, Germany
- Address correspondence to Andreas Hamann, MD, Division of Endocrinology and Metabolism, Department of Medicine, Im Neuenheimer Feld 410, D-69120 Heidelberg, Germany. E-mail: andreas_hamann{at}med.uni-heidelberg.de
Lin et al. (1) have recently reported a positive association of the SUMO4 M55V variant with diabetic nephropathy in an Asian cohort of 430 patients with type 2 diabetes. The authors found a strong association of the G allele with an increased risk for diabetic nephropathy.
Thus far, little is known about the physiologic role of …
