Response to Comment on: Lin et al. (2007) SUMO4 M55V Variant Is Associated With Diabetic Nephropathy in Type 2 Diabetes: Diabetes 56:1177–1180
- Shyi-Jang Shin12,
- Hsing-Yi Lin3,
- Chiao-Ling Wang2,
- Pi-Jung Hsiao1 and
- Kun-Der Lin13
- 1Division of Endocrinology and Metabolism, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
- 2Graduate Institute of Medical Genetics, Kaohsiung Medical University, Kaohsiung, Taiwan
- 3Graduate Institute of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
- Address correspondence to Shyi-Jang Shin, MD, PhD, Division of Endocrinology and Metabolism, Kaohsiung Medical University Hospital, 100 Shih-Chuan 1st Rd, Kaohsiung 80708, Taiwan. E-mail: sjshin{at}kmu.edu.tw
We thank Hamann et al. (1) for their interest in our study (2) and for demonstrating their results. They did not find the SUMO4 M55V variant to be associated with diabetic nephropathy in Caucasian patients with type 1 (n = 237) and type 2 (n = 515) diabetes. Our study had found the SUMO4 M55V variant to be associated with diabetic nephropathy in Taiwanese patients with type 2 diabetes (n = 430). We agree that these differences might be explained by the racial background, e.g., with Asian and Caucasian subjects.
In studies from Asian control populations, the frequencies of …
