Comment on: Harmancey et al. (2007) Adrenomedullin Inhibits Adipogenesis Under Transcriptional Control of Insulin: Diabetes 56:553–563
- From the Department of Analytical Medical Technology, Tohoku University School of Health Sciences, Sendai, Japan
- Address correspondence to Kazuhiro Takahashi, MD, PhD, Department of Analytical Medical Technology, Tohoku University School of Health Sciences, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan. E-mail: ktaka-md{at}mail.tains.tohoku.ac.jp
I have read with great interest the article by Harmancey et al. (1) on inhibition of adipogenesis by adrenomedullin. Previous studies, including ours (2–4), have shown that adrenomedullin is produced and secreted by adipocytes and adipose tissues, whereas the reported effects of adrenomedullin on lipolysis are conflicting (5,6). Harmancey et al. (1) have clearly shown inhibition of adipogenesis by adrenomedullin using …
